KEGG   ORTHOLOGY: K17726
Entry
K17726            Tight     KO                                     
Symbol
CYP4F2_3
Name
phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:1.14.14.78 1.14.14.79 1.14.14.94]
Pathway
map00590  Arachidonic acid metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.78  phylloquinone omega-hydroxylase
     K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase
    1.14.14.79  docosahexaenoic acid omega-hydroxylase
     K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase
    1.14.14.94  leukotriene-B4 20-monooxygenase
     K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP4 family
   K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase
Other DBs
RN: R03866 R07041
GO: 0050051
Genes
HSA: 4051(CYP4F3) 8529(CYP4F2)
PTR: 100609185 748117(CYP4F3) 748531(CYP4F2)
PPS: 100967411(CYP4F2) 100969141(CYP4F3)
GGO: 101125692 101135418 101152881
PON: 100434096 100437847 100453229
NLE: 100579320 100588006 115836968
MCC: 718349 719317
MCF: 102130440(CYP4F3) 102134301(CYP4F2)
CSAB: 103234079 103234089
CATY: 105601614 105601627
TFN: 117076174
CJC: 100411160 100412575(CYP4F2)
CSYR: 103250633
CPOC: 100733735
TUP: 102483333
VLG: 121495723
LLV: 125083145
ZCA: 113917975
MLX: 118005050
PKL: 118706555
DRO: 112305042
PDIC: 114503445
RFQ: 117038128
PGIG: 120606485
PVP: 105311420
RAY: 107517263
TOD: 119240020
LAV: 100657832
DNM: 101441145
 » show all
Reference
PMID:8026587 (CYP4F2)
  Authors
Kikuta Y, Kusunose E, Kondo T, Yamamoto S, Kinoshita H, Kusunose M
  Title
Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.
  Journal
FEBS Lett 348:70-4 (1994)
DOI:10.1016/0014-5793(94)00587-7
  Sequence
[hsa:8529]
Reference
PMID:8486631 (CYP4F3)
  Authors
Kikuta Y, Kusunose E, Endo K, Yamamoto S, Sogawa K, Fujii-Kuriyama Y, Kusunose M
  Title
A novel form of cytochrome P-450 family 4 in human polymorphonuclear leukocytes. cDNA cloning and expression of leukotriene B4 omega-hydroxylase.
  Journal
J Biol Chem 268:9376-80 (1993)
  Sequence
[hsa:4051]

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