KEGG   ORTHOLOGY: K17745
Entry
K17745                      KO                                     
Symbol
spr1
Name
sepiapterin reductase [EC:1.1.1.325]
Pathway
map00790  Folate biosynthesis
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00843  L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
Reaction
R09989  L-threo-7,8-dihydrobiopterin:NADP+ oxidoreductase
R09990  L-threo-tetrahydrobiopterin:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K17745  spr1; sepiapterin reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.325  sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
     K17745  spr1; sepiapterin reductase
Genes
CTE: CT0609
CPC: Cpar_0625
CLZ: BIU88_07960
CCH: Cag_0693
CPH: Cpha266_1763
CPB: Cphamn1_0828
CLI: Clim_1820
PVI: Cvib_1180
PLT: Plut_0596
PPH: Ppha_0933
PAA: Paes_0733
CTS: Ctha_0970
 » show all
Reference
  Authors
Cho SH, Na JU, Youn H, Hwang CS, Lee CH, Kang SO
  Title
Sepiapterin reductase producing L-threo-dihydrobiopterin from Chlorobium tepidum.
  Journal
Biochem J 340 ( Pt 2):497-503 (1999)
DOI:10.1042/bj3400497
  Sequence
[cte:CT0609]

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