KEGG   ORTHOLOGY: K18389
Entry
K18389                      KO                                     

Name
PAXQ, ATMQ, CYP698A
Definition
cytochrome P450 monooxygenase [EC:1.14.13.-]
Pathway
ko00403  Indole diterpene alkaloid biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00403 Indole diterpene alkaloid biosynthesis
    K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP698 family
   K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
Other DBs
RN: R10359 R10361 R10362
COG: COG2124
Genes
AOR: AO090011000739
AFV: AFLA_045500
AG: AAK11527(PAXQ)
Reference
  Authors
Tagami K, Minami A, Fujii R, Liu C, Tanaka M, Gomi K, Dairi T, Oikawa H
  Title
Rapid reconstitution of biosynthetic machinery for fungal metabolites in Aspergillus oryzae: total biosynthesis of aflatrem.
  Journal
Chembiochem 15:2076-80 (2014)
DOI:10.1002/cbic.201402195
Reference
  Authors
Nicholson MJ, Koulman A, Monahan BJ, Pritchard BL, Payne GA, Scott B
  Title
Identification of two aflatrem biosynthesis gene loci in Aspergillus flavus and metabolic engineering of Penicillium paxilli to elucidate their function.
  Journal
Appl Environ Microbiol 75:7469-81 (2009)
DOI:10.1128/AEM.02146-08
  Sequence
Reference
  Authors
Young C, McMillan L, Telfer E, Scott B
  Title
Molecular cloning and genetic analysis of an indole-diterpene gene cluster from Penicillium paxilli.
  Journal
Mol Microbiol 39:754-64 (2001)
DOI:10.1046/j.1365-2958.2001.02265.x
  Sequence

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