KEGG   ORTHOLOGY: K18750Help
Entry
K18750                      KO                                     

Name
APOBEC3
Definition
C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
Pathway
ko05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K18750  APOBEC3; C->U-editing enzyme APOBEC3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K18750  APOBEC3; C->U-editing enzyme APOBEC3
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.-  
     K18750  APOBEC3; C->U-editing enzyme APOBEC3
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     K18750  APOBEC3; C->U-editing enzyme APOBEC3
BRITE hierarchy
Genes
HSA: 100913187(APOBEC3A_B) 140564(APOBEC3D) 164668(APOBEC3H) 200315(APOBEC3A) 200316(APOBEC3F) 27350(APOBEC3C) 60489(APOBEC3G) 9582(APOBEC3B)
PTR: 100611714(APOBEC3C) 449577(APOBEC3G) 467121 470214(APOBEC3H) 470274(APOBEC3D) 470275 743891(APOBEC3B) 744498(APOBEC3A)
PPS: 100971498(APOBEC3B) 100975653 100982453(APOBEC3G) 100983444(APOBEC3C) 100983664(APOBEC3H)
GGO: 101133558 101133902 101134601 101137376(APOBEC3G)
PON: 100455142(APOBEC3A) 100456583(APOBEC3F) 100458043(APOBEC3G) 100458762 103888537(APOBEC3C)
NLE: 100583627 100585149(APOBEC3A) 100585498(APOBEC3D) 100585723(APOBEC3C) 100585834(APOBEC3H) 100601000(APOBEC3G) 108684025(APOBEC3B) 115835901 115836019
MCC: 574398(APOBEC3G) 705870(APOBEC3C) 705996(APOBEC3D) 721030(APOBEC3A) 721047(APOBEC3B) 723811(APOBEC3H) 723812(APOBEC3F)
MCF: 101925624(APOBEC3C) 102126615(APOBEC3B) 102127357(APOBEC3D) 102128261(APOBEC3G) 102129411(APOBEC3H) 102131077(APOBEC3A) 107126386(APOBEC3F)
CSAB: 103223331(APOBEC3D) 103223333(APOBEC3C) 103223334(APOBEC3G) 103223335(APOBEC3H) 103247808 108663998(APOBEC3B)
RRO: 104682550(APOBEC3H) 104682552(APOBEC3G) 104682553(APOBEC3F) 104682554(APOBEC3D) 104682555(APOBEC3B) 104682557(APOBEC3A) 108684023(APOBEC3C)
RBB: 108520475(APOBEC3G) 108520477(APOBEC3H) 108521436(APOBEC3A) 108521467 108521468 108521469 108526035
MMU: 80287(Apobec3)
MCAL: 110310320
MPAH: 110334948
RNO: 315137(Apobec3b)
MUN: 110557822
CGE: 100772476(Apobec3b)
NGI: 103748572
CCAN: 109692930
OCU: 100340649 103348387(APOBEC3A)
CFA: 481248(APOBEC3Z3) 610245(APOBEC3Z1)
VVP: 112934047
UMR: 103659212(APOBEC3H) 103676525(APOBEC3F) 103681381
UAH: 113241577 113241590 113251074(APOBEC3H)
ORO: 101378154(APOBEC3B) 105757446(APOBEC3H)
FCA: 100127022(APOBEC3Z3)
PTG: 102971284
AJU: 106981073
BTA: 108771180(APOBEC3Z3) 504505(APOBEC3Z2) 507162(APOBEC3Z1)
BIU: 109558629
BBUB: 102405577 112584444(APOBEC3A)
CHX: 102184324 106502146(APOBEC3A)
OAS: 100037691(APOBEC3F) 100301555(APOBEC3Z1)
SSC: 100037939(APOBEC3B)
CFR: 102512329(APOBEC3G) 106728592
CDK: 105091988
BACU: 103013586(APOBEC3G) 103014141(APOBEC3B)
LVE: 103069082(APOBEC3G) 103086070(APOBEC3B)
ECB: 100070206 100070250(APOBEC3Z2A-Z2) 100070262(APOBEC3H) 100146802 100147481(A3F2) 100302571
HAI: 109392229 109392257(APOBEC3H) 109394478
RAY: 107502060(APOBEC3F) 107502068(APOBEC3H) 107502069 107507997 107519218(APOBEC3A)
MJV: 108386308(APOBEC3A)
MDO: 103099360
SHR: 100914817
PCW: 110192697
ACS: 103278301
PVT: 110088515
PMUA: 114596543
GJA: 107115394
XLA: 108709754
SFM: 108928992
PKI: 111859667
DGT: 114518497
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wedekind JE, Dance GS, Sowden MP, Smith HC
  Title
Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.
  Journal
Trends Genet 19:207-16 (2003)
DOI:10.1016/S0168-9525(03)00054-4
  Sequence
Reference
  Authors
Gallois-Montbrun S, Kramer B, Swanson CM, Byers H, Lynham S, Ward M, Malim MH
  Title
Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules.
  Journal
J Virol 81:2165-78 (2007)
DOI:10.1128/JVI.02287-06
  Sequence
[hsa:60489]
Reference
  Authors
Madsen P, Anant S, Rasmussen HH, Gromov P, Vorum H, Dumanski JP, Tommerup N, Collins JE, Wright CL, Dunham I, MacGinnitie AJ, Davidson NO, Celis JE
  Title
Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1.
  Journal
J Invest Dermatol 113:162-9 (1999)
DOI:10.1046/j.1523-1747.1999.00682.x
  Sequence
[hsa:200315]

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