KEGG   ORTHOLOGY: K18768Help
Entry
K18768            Tight     KO                                     

Name
blaKPC
Definition
beta-lactamase class A KPC [EC:3.5.2.6]
Pathway
ko01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Drug resistance
   01501 beta-Lactam resistance
    K18768  blaKPC; beta-lactamase class A KPC
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18768  blaKPC; beta-lactamase class A KPC
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class A [MT]
    K18768  blaKPC; beta-lactamase class A KPC
BRITE hierarchy
Other DBs
COG: COG2367
GO: 0008800
Genes
ECLE: ECNIH2_24690 ECNIH2_25815 ECNIH2_26880
ECLN: ECNIH4_23585
ECLI: ECNIH5_23470
ECLX: LI66_24385
ECLY: LI62_00245
ECLZ: LI64_22410
ECLA: ECNIH3_24215
ECLC: ECR091_23505
EHM: AB284_00545
ECLS: LI67_024640 LI67_024910
KPNE: KU54_01135
KPNU: LI86_28510
AG: AAG13410(KPC-1) AAK70220(KPC-2) AAL05630(KPC-3) ABY91240(KPC-5) ACB71165(KPC-6) ACE62798(KPC-7) ACI95258(KPC-8) ACL01102(KPC-4) ACM91559(KPC-9) ACS35345(KPC-10) ADH95186(KPC-11) ADZ75467(KPC-12) AEA73284(KPC-13) AFV48348(KPC-14) AGF70638(KPC-15) AGJ01153(KPC-16) AGJ01154(KPC-17) AIH07017(KPC-19) AIX87991(KPC-22) AKO63215(KPC-18) AKQ06274(KPC-24) ALS19383(KPC-25) ANY26940(KPC-26) AOR05747(KPC-27) APG42690(KPC-28) AQT03460(KPC-30) CEF57509(KPC-21) OKK72649(KPC-31) OKL07573(KPC-32)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, Alberti S, Bush K, Tenover FC
  Title
Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae.
  Journal
Antimicrob Agents Chemother 45:1151-61 (2001)
DOI:10.1128/AAC.45.4.1151-1161.2001
  Sequence

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