KEGG ORTHOLOGY: K19361

ORTHOLOGY: K19361

Entry

K19361                      KO

Symbol

TCTN2

Name

tectonic-2

Disease

H00261

Meckel syndrome

H00530

Joubert syndrome and related disorders

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K19361  TCTN2; tectonic-2
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  MKS complex
   K19361  TCTN2; tectonic-2

Genes

HSA:	79867(TCTN2)

PTR:	100615573(TCTN2)

PPS:	100974621(TCTN2)

GGO:	101146235(TCTN2)

PON:	100454231(TCTN2)

PPYG:

129010415(TCTN2)

NLE:	100581318(TCTN2)

HMH:	116477725(TCTN2)

SSYN:

129460323(TCTN2)

MCC:	721415(TCTN2)

MCF:	102127899(TCTN2)

MTHB:

126930617

MNI:	105493893(TCTN2)

CSAB:

103239337(TCTN2)

CATY:

105591012(TCTN2)

PANU:

101014928(TCTN2)

TGE:	112634598(TCTN2)

MLEU:

105545848(TCTN2)

RRO:	104666366(TCTN2)

RBB:	108540648(TCTN2)

TFN:	117089208(TCTN2)

PTEH:

111538584(TCTN2)

CANG:

105516293(TCTN2)

CJC:	100896306(TCTN2)

SBQ:	101037751(TCTN2)

CIMI:

108315199(TCTN2)

ANAN:

105713401(TCTN2)

MMUR:

105880861(TCTN2)

LCAT:

123626126(TCTN2)

PCOQ:

105825688(TCTN2)

OGA:	100956937(TCTN2)

MMU:	67978(Tctn2)

MCAL:

110294939(Tctn2)

MPAH:

110312937(Tctn2)

RNO:	689779(Tctn2)

MCOC:

116068439(Tctn2)

ANU:	117697947(Tctn2)

MUN:	110552680(Tctn2)

CGE:	100768551(Tctn2)

MAUA:

101835092(Tctn2)

PROB:

127236952(Tctn2)

PLEU:

114704509(Tctn2)

MORG:

121446554(Tctn2)

MFOT:

126504314

AAMP:

119825524(Tctn2)

NGI:	103739022(Tctn2)

HGL:	101698943(Tctn2)

CPOC:

101787809(Tctn2)

CCAN:

109684878(Tctn2)

DORD:

105990609(Tctn2)

DSP:	122098532(Tctn2)

PLOP:

125349201(Tctn2)

NCAR:

124990220

MMMA:

107156379(Tctn2)

OCU:

103346105

OPI:	101517598(TCTN2)

TUP:	102469987(TCTN2)

GVR:	103606948(TCTN2)

CFA:	477445(TCTN2)

CLUD:

112676453(TCTN2)

VVP:	112933820(TCTN2)

VLG:	121475859(TCTN2)

NPO:	129508198(TCTN2)

AML:	105238177(TCTN2)

UMR:	103661251(TCTN2)

UAH:	113266888(TCTN2)

UAR:	123779988(TCTN2)

ELK:

111156539

LLV:

125081903

MPUF:

101684795(TCTN2)

MNP:	132023084(TCTN2)

MLK:	131811371(TCTN2)

NVS:	122903079(TCTN2)

ORO:	101382686(TCTN2)

EJU:	114200370(TCTN2)

ZCA:	113912941(TCTN2)

MLX:	118018393(TCTN2)

NSU:	110588318(TCTN2)

LWW:	102735287(TCTN2)

FCA:	101085243(TCTN2)

PYU:	121010406(TCTN2)

PCOO:

112870289(TCTN2)

PBG:	122470139(TCTN2)

PVIV:

125149568(TCTN2)

LRUF:

124518171

PTG:	102959363(TCTN2)

PPAD:

109277751(TCTN2)

PUC:

125914256

AJU:

106978343

HHV:	120236642(TCTN2)

BTA:	100847961(TCTN2)

BOM:	102266395(TCTN2)

BIU:	109571483(TCTN2)

BBUB:

102416029(TCTN2)

BBIS:

104989573(TCTN2)

CHX:	102180068(TCTN2)

OAS:	101121804(TCTN2)

BTAX:

128062321(TCTN2)

ODA:	120871038(TCTN2)

CCAD:

122424484(TCTN2)

MREE:

136146066(TCTN2)

MBEZ:

129542710(TCTN2)

SSC:	100153315(TCTN2)

CFR:	102522788(TCTN2)

CBAI:

105080671(TCTN2)

CDK:	105094333(TCTN2)

VPC:	107034084(TCTN2)

BACU:

103001875(TCTN2)

BMUS:

118906628(TCTN2)

LVE:	103074372(TCTN2)

OOR:	101276861(TCTN2)

DLE:	111186951(TCTN2)

PCAD:

102986238(TCTN2)

PSIU:

116738764(TCTN2)

NASI:

112408849(TCTN2)

ECB:	100630826(TCTN2)

EPZ:	103549890(TCTN2)

EAI:	106842342(TCTN2)

MYB:	102247644(TCTN2)

MYD:	102762275(TCTN2)

MMYO:

118655517(TCTN2)

MLF:	102436026(TCTN2)

MDT:	132221882(TCTN2)

PKL:	118710435(TCTN2)

EFUS:

103300386(TCTN2)

MNA:	107529652(TCTN2)

DRO:	112310804(TCTN2)

SHON:

118991019(TCTN2)

AJM:	119060811(TCTN2)

PDIC:

114509644(TCTN2)

PHAS:

123822717(TCTN2)

MMF:	118639953(TCTN2)

PPAM:

129087394(TCTN2)

HAI:	109386113(TCTN2)

RFQ:	117017187(TCTN2)

PALE:

102896004(TCTN2)

PGIG:

120616013(TCTN2)

PVP:	105289363(TCTN2)

RAY:	107515199(TCTN2)

MJV:	108409907(TCTN2)

TOD:	119245060(TCTN2)

SARA:

101539344(TCTN2)

SETR:

126002052(TCTN2)

LAV:	100662238(TCTN2)

TMU:

101353772

ETF:	101642580(TCTN2)

DNM:	101440566(TCTN2)

MDO:	103106109(TCTN2)

GAS:	123256847(TCTN2)

SHR:	100934845(TCTN2)

AFZ:

127545394

PCW:	110196838(TCTN2)

TVP:	118834331(TCTN2)

OAA:	114809074(TCTN2)

GGA:	100857705(TCTN2)

PCOC:

116228642(TCTN2)

MGP:	104913534(TCTN2)

CJO:	107321172(TCTN2)

TPAI:

128084616(TCTN2)

LMUT:

125701839(TCTN2)

NMEL:

110406286(TCTN2)

APLA:

110352116(TCTN2)

ACYG:

106031421(TCTN2)

CATA:

118257237(TCTN2)

AFUL:

116496319(TCTN2)

TGU:	101233444(TCTN2)

LSR:	110471804(TCTN2)

SCAN:

103818191(TCTN2)

PMOA:

120509630(TCTN2)

OTC:	121338888(TCTN2)

PRUF:

121364919(TCTN2)

GFR:	102037325(TCTN2)

FAB:	101806313(TCTN2)

OMA:	130259672(TCTN2)

PHI:	102107544(TCTN2)

PMAJ:

107211428(TCTN2)

CCAE:

111936359(TCTN2)

CCW:	104688728(TCTN2)

CBRC:

103616012(TCTN2)

ETL:	114054948(TCTN2)

ZAB:	102075474(TCTN2)

ZLE:	135454514(TCTN2)

ACHL:

103811346(TCTN2)

SVG:	106852476(TCTN2)

MMEA:

130580997(TCTN2)

HRT:	120760740(TCTN2)

SATI:

136369093(TCTN2)

FPG:	101914041(TCTN2)

FCH:	102052637(TCTN2)

CCRI:

104154850(TCTN2)

NNT:

104399419

SHAB:

115614950(TCTN2)

ACUN:

113486154(TCTN2)

TALA:

104355604(TCTN2)

ACHC:

115345788(TCTN2)

HALD:

104310759(TCTN2)

HLE:	104840928(TCTN2)

AGEN:

126040318

GCL:

127022853

CSTI:

104549723(TCTN2)

LDI:	104340166(TCTN2)

MNB:	103772789(TCTN2)

DPUB:

104308464(TCTN2)

AVIT:

104267371(TCTN2)

BRHI:

104497226(TCTN2)

EGZ:	104130154(TCTN2)

NNI:	104020941(TCTN2)

PCRI:

104030322(TCTN2)

PCAO:

104047876(TCTN2)

PADL:

103914545(TCTN2)

AFOR:

103902874(TCTN2)

FGA:	104069484(TCTN2)

GSTE:

104250661(TCTN2)

CLV:	102090515(TCTN2)

MUI:	104545736(TCTN2)

PGUU:

104457811(TCTN2)

PLET:

104613980(TCTN2)

EHS:	104503525(TCTN2)

CMAC:

104473810(TCTN2)

CUCA:

104068457(TCTN2)

TEO:	104370181(TCTN2)

BREG:

104629438(TCTN2)

OHA:	104327603(TCTN2)

ACAR:

104518387(TCTN2)

CPEA:

104388758(TCTN2)

CVF:	104282251(TCTN2)

RTD:	128917057(TCTN2)

AAM:	106497680(TCTN2)

AROW:

112962525(TCTN2)

NPD:	112945869(TCTN2)

TGT:	104574848(TCTN2)

DNE:	112991866(TCTN2)

SCAM:

104138823(TCTN2)

ASN:	102380461(TCTN2)

AMJ:	102570862(TCTN2)

CPOO:

109312715(TCTN2)

GGN:	109290509(TCTN2)

PSS:	102449285(TCTN2)

CMY:	102947079(TCTN2)

CCAY:

125622801(TCTN2)

DCC:	119843937(TCTN2)

TST:	117887882(TCTN2)

CABI:

116836746(TCTN2)

ACS:	103279290(tctn2)

ASAO:

132781359(TCTN2)

PVT:	110083825(TCTN2)

SUND:

121916493(TCTN2)

PBI:	103055282(TCTN2)

PMUR:

107285457(TCTN2)

CTIG:

120316676(TCTN2)

TSR:	106552087(TCTN2)

PGUT:

117672145(TCTN2)

APRI:

131185678(TCTN2)

PTEX:

113448605(TCTN2)

NSS:	113425029(TCTN2)

VKO:	123028563(TCTN2)

PMUA:

114586287 114586288

PRAF:

128403670(TCTN2)

ZVI:	118075717(TCTN2)

HCG:	128337998(TCTN2)

GJA:	107117228(TCTN2)

STOW:

125443154(TCTN2)

EMC:	129341318(TCTN2)

XLA:	108695669(tctn2.L)

XTR:	733954(tctn2)

NPR:	108787377(TCTN2)

RTEM:

120934689(TCTN2)

BBUF:

120991406(TCTN2)

BGAR:

122924510(TCTN2)

MUO:	115479623(TCTN2)

GSH:	117365191(TCTN2)

DRE:	563835(tctn2)

SRX:

SANH:

SGH:

CCAR:

CAUA:

113068078(tctn2)

CGIB:

127958567

PTET:

122345962(tctn2)

LROH:

127164736(tctn2)

OMC:	131540071(tctn2)

PPRM:

120470448(tctn2)

RKG:	130088105(tctn2)

MAMB:

125267345(tctn2)

CIDE:

127512187

CERY:

137034360(tctn2)

MASI:

127418231

TROS:

130568639(tctn2)

TDW:	130419510(tctn2)

MANU:

129439710 129439726

IPU:

108255514

IFU:	128598998(tctn2)

PHYP:

113536938(tctn2)

SMEO:

124380438(tctn2)

TFD:	113653316(tctn2)

TVC:	132855175(tctn2)

TRN:	134335701(tctn2)

AMEX:

103022260(tctn2)

CMAO:

118827720(tctn2)

EEE:	113585584(tctn2)

CHAR:

105896798(tctn2)

TRU:	105418033(tctn2)

TFS:	130525592(tctn2)

LCO:	104920369(tctn2)

NCC:	104950173(tctn2)

TBEN:

117496848(tctn2)

CGOB:

115013695(tctn2)

PGEO:

117452696(tctn2)

GACU:

117561117(tctn2)

EMAC:

134873429(tctn2)

ELY:	117252325(tctn2)

EFO:	125890057(tctn2)

PLEP:

121944853(tctn2)

ECRA:

117945011(tctn2)

PFLV:

114555531(tctn2)

GAT:	120830252(tctn2)

PPUG:

119225359(tctn2)

AFB:	129101586(tctn2)

CLUM:

117736287(tctn2)

PSWI:

130197416(tctn2)

CANA:

137805244(tctn2)

MSAM:

119892299(tctn2)

SCHU:

122876255(tctn2)

CUD:	121509954(tctn2)

ALAT:

119019494(tctn2)

ASTR:

137592362(tctn2)

MZE:	101468351(tctn2)

ONL:	102079034(tctn2)

OAU:	116332358(tctn2)

OLA:	101155357(tctn2)

OML:	112147884(tctn2)

CSAI:

133451260(tctn2)

XMA:	102223260(tctn2)

XCO:	114155275(tctn2)

XHE:	116730484(tctn2)

PRET:

103470301(tctn2)

PFOR:

103142851(tctn2)

PLAI:

106937145(tctn2)

PMEI:

106918065(tctn2)

GAF:	122827929(tctn2)

PPRL:

129371951(tctn2)

CVG:	107091234 107091235

CTUL:

119790099(tctn2)

GMU:	124878016(tctn2)

NFU:	107394197(tctn2)

KMR:	108234483(tctn2)

ALIM:

106521673(tctn2)

NWH:	119413364(tctn2)

AOCE:

111575839(tctn2)

MCEP:

125012140(tctn2)

CSEM:

103398614(tctn2)

POV:	109638114(tctn2)

SSEN:

122769923(tctn2)

HHIP:

117768244(tctn2)

HSP:	118114463(tctn2)

PPLT:

128438293(tctn2)

SMAU:

118314502(tctn2)

LCF:

108878007

SDU:	111230213(tctn2)

SLAL:

111660295(tctn2)

XGL:	120804764(tctn2)

HCQ:	109511652(tctn2)

SSCV:

125994491(tctn2)

SBIA:

133499218(tctn2)

PEE:	133400520(tctn2)

PTAO:

133475487(tctn2)

BPEC:

110169781(tctn2)

MALB:

109961571(tctn2)

BSPL:

114862178(tctn2)

SJO:	128365034(tctn2)

SASA:

106580323(tctn2)

STRU:

115200201(tctn2)

OTW:	112248519(tctn2)

OMY:	110536100(tctn2)

OGO:	124035223(tctn2)

ONE:	115140110(tctn2)

OKI:	109895955(tctn2)

OKE:	118358398(tctn2)

SALP:

111958227(tctn2)

SNH:	120062659(tctn2)

CCLU:

121587355(tctn2)

ELS:	105025612(tctn2)

SFM:	108932531(tctn2)

PKI:	111839977(tctn2)

AANG:

118206429(tctn2)

LOC:	102687252(tctn2)

PSPA:

121299892(tctn2)

ARUT:

117427098 117963183

PSEX:

120540881(tctn2)

LCM:	102351376(TCTN2)

CMK:	103188003(tctn2)

RTP:

109936925

CPLA:

122551018(tctn2)

HOC:	132826995(tctn2)

LERI:

129709240(tctn2)

PMRN:

116939203

LRJ:	133348340(TCTN2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

ZNE:

CSEC:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

EAF:

LSM:

TCF:

CSCU:

CVS:

LGI:	LOTGIDRAFT_228304

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:	107332547 107332821

AMIL:

PDAM:

SPIS:

DGT:

XEN:

Reference

PMID:16357211

Authors

Reiter JF, Skarnes WC

Title

Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.

Journal

Genes Dev 20:22-7 (2006)
DOI:10.1101/gad.1363606

Sequence

[hsa:79867]

All links

Ontology (2)   
   KEGG BRITE (2)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (686)   
   KEGG GENES (456)   
   KEGG MGENES (77)   
   RefGene (148)   
   OC (5)   
Literature (1)   
   PubMed (1)   
All databases (691)   

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