KEGG   ORTHOLOGY: K19719Help
Entry
K19719                      KO                                     

Name
COL2A
Definition
collagen, type II, alpha
Pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04974  Protein digestion and absorption
ko05165  Human papillomavirus infection
Disease
H00445  Osteoarthritis with mild chondrodysplasia
H00476  Multiple epiphyseal dysplasia
H00519  Spondyloepiphyseal dysplasia congenita
H00520  Type II collagenopathies
H00805  Vitreoretinal degeneration
H01526  Legg-Calve-Perthes Disease
H01529  Avascular necrosis of femoral head
H01709  Glucocorticoid-induced osteonecrosis
H02066  Achondrogenesis type II
H02070  Kniest dysplasia
H02071  Czech dysplasia
H02072  Stickler syndrome
H02187  Spondyloepimetaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K19719  COL2A; collagen, type II, alpha
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K19719  COL2A; collagen, type II, alpha
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K19719  COL2A; collagen, type II, alpha
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    K19719  COL2A; collagen, type II, alpha
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K19719  COL2A; collagen, type II, alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K19719  COL2A; collagen, type II, alpha
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   K19719  COL2A; collagen, type II, alpha
BRITE hierarchy
Genes
HSA: 1280(COL2A1)
PTR: 451860(COL2A1)
PPS: 100983139(COL2A1)
GGO: 101127576(COL2A1)
PON: 100433193(COL2A1)
NLE: 100588525(COL2A1) 100601980(CAMK2N1)
MCC: 704851(COL2A1)
MCF: 102134921(COL2A1)
CSAB: 103218301 103238216(COL2A1)
RRO: 104654840(COL2A1)
RBB: 108515958(COL2A1)
CJC: 100400909(COL2A1)
SBQ: 101041402(COL2A1)
MMU: 12824(Col2a1)
RNO: 25412(Col2a1)
CGE: 100755037(Col2a1) 113834683
NGI: 103740626(Col2a1)
HGL: 101707672(Col2a1)
CCAN: 109675441 109691615(Col2a1)
OCU: 100009005(COL2A1)
TUP: 102470303(COL2A1)
CFA: 403826(COL2A1)
AML: 100474711(COL2A1)
UMR: 103675428(COL2A1)
ORO: 101370480(COL2A1) 105757839
FCA: 101087493(COL2A1)
PTG: 102956312(COL2A1)
AJU: 106969351(COL2A1)
BTA: 407142(COL2A1)
BOM: 102284180(COL2A1)
BIU: 109559169(COL2A1)
PHD: 102318164(COL2A1)
CHX: 100860743(COL2A1) 108634587
OAS: 100196905(COL2A1)
SSC: 397323(COL2A1)
CFR: 102516074(COL2A1)
CDK: 105103802(COL2A1)
LVE: 103078299(COL2A1)
OOR: 101276952(COL2A1)
ECB: 791241(COL2A1)
EPZ: 103546826(COL2A1)
EAI: 106836837(COL2A1)
MYB: 102248763 102254720(COL2A1)
MYD: 102768294(COL2A1)
MNA: 107528223(COL2A1)
HAI: 109372512(COL2A1)
RSS: 109456246(COL2A1)
PALE: 102894333(COL2A1)
LAV: 100675826(COL2A1) 111748363
TMU: 101343281
MDO: 100027887
SHR: 100915177(COL2A1)
PCW: 110201505(COL2A1)
OAA: 100091569(COL2A1)
GGA: 395069(COL2A1)
MGP: 100540311(COL2A1)
CJO: 107306964(COL2A1)
APLA: 106014712(COL2A1)
ACYG: 106049583(COL2A1)
LSR: 110480541(COL2A1) 110481422
SCAN: 103824964
GFR: 102031754(COL2A1)
PHI: 102111968(COL2A1)
PMAJ: 107198731(COL2A1)
CCAE: 111940513(COL2A1) 111944097
FPG: 101919991(COL2A1)
FCH: 102059900(COL2A1)
CLV: 102092442(COL2A1)
EGZ: 104126835
NNI: 104017542(COL2A1)
AAM: 106484126
ASN: 102371324(COL2A1)
AMJ: 102576638(COL2A1)
CMY: 102932287(COL2A1)
CPIC: 101949909(COL2A1)
ACS: 100553016(col2a1)
PVT: 110071756(COL2A1)
PBI: 103059733(COL2A1)
PMUR: 107288503(COL2A1)
GJA: 107120677
XLA: 397738(col2a1.L) 397739(col2a1.S)
XTR: 394828(col2a1)
NPR: 108800103(COL2A1)
DRE: 503730(col2a1b) 562496(col2a1a)
IPU: 108265655(col2a1)
PHYP: 113527853
OLA: 100529192 100682394(col2a1a)
LCM: 102359526(COL2A1)
CMK: 103189017(col1a2) 103189947(col2a1)
SPU: 373267(COLP1alpha)
SKO: 100303513
MDE: 101889347
AAG: 110678066
AME: 410038
BIM: 100743696
BTER: 100649253
SOC: 105208111
MPHA: 105837322
AEC: 105154648
ACEP: 105622491
PBAR: 105432212
HST: 105190388
DQU: 106750023
CFO: 105250620
LHU: 105673720
PGC: 109851614
OBO: 105285658
PCF: 106791787
NVI: 100120054
TCA: 660112
DPA: 109540705
NVL: 108568888
BMOR: 101746136
PMAC: 106712876
PRAP: 110999882
HAW: 110375333
TNL: 113496840
API: 100164192
DNX: 107169123
AGS: 114130153
CLEC: 106669954
ZNE: 110840376
FCD: 110856657
TUT: 107368669
OBI: 106868320
EGL: EGR_01301
HMG: 100211987(col2)
AQU: 100634948
DZI: 111291639
NAU: 109221393
APRO: F751_6789
ABP: AGABI1DRAFT128802(AGABI1DRAFT_128802)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gordon MK, Hahn RA
  Title
Collagens.
  Journal
Cell Tissue Res 339:247-57 (2010)
DOI:10.1007/s00441-009-0844-4
Reference
  Authors
Muller S, Soder S, Oliveira AM, Inwards CY, Aigner T
  Title
Type II collagen as specific marker for mesenchymal chondrosarcomas compared to other small cell sarcomas of the skeleton.
  Journal
Mod Pathol 18:1088-94 (2005)
DOI:10.1038/modpathol.3800391
  Sequence
[hsa:1280]
Reference
PMID:2587267
  Authors
Su MW, Lee B, Ramirez F, Machado M, Horton W
  Title
Nucleotide sequence of the full length cDNA encoding for human type II procollagen.
  Journal
Nucleic Acids Res 17:9473 (1989)
DOI:10.1093/nar/17.22.9473
  Sequence
[hsa:1280]

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