KEGG   ORTHOLOGY: K19722
Entry
K19722                      KO                                     

Name
AGER, RAGE
Definition
receptor for advanced glycosylation end products
Pathway
ko04613  Neutrophil extracellular trap formation
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05415  Diabetic cardiomyopathy
ko05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
   05022 Pathways of neurodegeneration - multiple diseases
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
   05415 Diabetic cardiomyopathy
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
Other DBs
GO: 0050785
Genes
HSA: 177(AGER)
PTR: 462584(AGER)
PPS: 100988780(AGER)
GGO: 101150956(AGER)
PON: 100443859(AGER)
NLE: 101178250(AGER)
MCC: 717296(AGER)
MCF: 102121124(AGER)
CSAB: 103221709(AGER)
RRO: 104673948(AGER)
RBB: 108519888(AGER) 108524385
CJC: 100414002(AGER)
SBQ: 101043104(AGER)
MMU: 11596(Ager)
MCAL: 110312645(Ager)
MPAH: 110335608(Ager)
RNO: 81722(Ager)
MUN: 110565392(Ager)
CGE: 100757624(Ager)
NGI: 103724405(Ager)
HGL: 101709133(Ager)
CCAN: 109690410(Ager)
OCU: 100343142(AGER)
TUP: 102486051(AGER)
CFA: 403168(AGER)
VVP: 112913637(AGER)
AML: 100477105(AGER)
UMR: 103682274(AGER)
UAH: 113243764(AGER)
ORO: 101383547(AGER)
ELK: 111152179
FCA: 101096892(AGER)
PTG: 102963427(AGER)
PPAD: 109260522(AGER)
AJU: 106983491(AGER)
BTA: 280986(AGER)
BOM: 102266016(AGER)
BIU: 109577209(AGER)
BBUB: 102399460(AGER)
CHX: 102168873(AGER)
OAS: 101111586(AGER)
SSC: 396591(AGER)
CFR: 102523226(AGER)
CDK: 105090848(AGER)
BACU: 103013422(AGER)
LVE: 103089458(AGER)
OOR: 101275831(AGER)
DLE: 111170949(AGER)
PCAD: 102976074(AGER)
ECB: 100051699(AGER)
EPZ: 103566647(AGER)
EAI: 106831014(AGER)
MYB: 102258384(AGER)
MYD: 102752127(AGER)
MNA: 107538992(AGER)
HAI: 109373121(AGER)
DRO: 112302184(AGER)
PALE: 102896393(AGER)
RAY: 107498452(AGER)
MJV: 108393802(AGER)
LAV: 100661497(AGER)
TMU: 101354153
MDO: 100024116(AGER)
SHR: 100933743(AGER)
PCW: 110199342(AGER)
OAA: 100090019(AGER)
LCM: 102360629(AGER)
 » show all
Reference
PMID:1378843
  Authors
Neeper M, Schmidt AM, Brett J, Yan SD, Wang F, Pan YC, Elliston K, Stern D, Shaw A
  Title
Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.
  Journal
J Biol Chem 267:14998-5004 (1992)
  Sequence
[hsa:177]
Reference
  Authors
Hudson BI, Carter AM, Harja E, Kalea AZ, Arriero M, Yang H, Grant PJ, Schmidt AM
  Title
Identification, classification, and expression of RAGE gene splice variants.
  Journal
FASEB J 22:1572-80 (2008)
DOI:10.1096/fj.07-9909com
Reference
  Authors
Fang F, Lue LF, Yan S, Xu H, Luddy JS, Chen D, Walker DG, Stern DM, Yan S, Schmidt AM, Chen JX, Yan SS
  Title
RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.
  Journal
FASEB J 24:1043-55 (2010)
DOI:10.1096/fj.09-139634
  Sequence
[hsa:177]

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