KEGG ORTHOLOGY: K19752

ORTHOLOGY: K19752

Entry

K19752                      KO

Symbol

DNAAF3, PF22

Name

dynein axonemal assembly factor 3

Disease

H00564

Primary ciliary dyskinesia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K19752  DNAAF3, PF22; dynein axonemal assembly factor 3
   04812 Cytoskeleton proteins
    K19752  DNAAF3, PF22; dynein axonemal assembly factor 3
Cilium and associated proteins [BR:ko03037]
Motile cilia and associated proteins
  Dynein assembly factors
   K19752  DNAAF3, PF22; dynein axonemal assembly factor 3
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     Dynein-related proteins
      K19752  DNAAF3, PF22; dynein axonemal assembly factor 3

Genes

HSA:	352909(DNAAF3)

PTR:	735574(DNAAF3)

PPS:	100985698(DNAAF3)

GGO:	101137368(DNAAF3)

PON:	100446190(DNAAF3)

NLE:	100596507(DNAAF3)

HMH:	116479210(DNAAF3)

MCC:	698780(DNAAF3)

MCF:	102145427(DNAAF3)

MTHB:

126943207

MNI:	105496972(DNAAF3)

CSAB:

103235293(DNAAF3)

CATY:

105582743(DNAAF3)

PANU:

101014398(DNAAF3)

TGE:

112611943

MLEU:

105551676(DNAAF3)

RRO:	104674759(DNAAF3)

RBB:	108542534(DNAAF3)

TFN:	117091727(DNAAF3)

PTEH:

111521181(DNAAF3)

CANG:

105504942(DNAAF3)

CJC:	128930411(DNAAF3)

SBQ:	101046724(DNAAF3)

CIMI:

108316610(DNAAF3)

CSYR:

103267497(DNAAF3)

MMUR:

105877195(DNAAF3)

LCAT:

123624690(DNAAF3)

PCOQ:

105809406(DNAAF3)

OGA:	100941012(DNAAF3)

MMU:	436022(Dnaaf3)

MCAL:

110298720(Dnaaf3)

MPAH:

110337023(Dnaaf3)

RNO:	100359753(Dnaaf3)

MCOC:

116101546(Dnaaf3)

ANU:	117701208(Dnaaf3)

MUN:	110561051(Dnaaf3)

CGE:

113831488

MAUA:

101840964(Dnaaf3)

PROB:

127238802(Dnaaf3)

PLEU:

114689155(Dnaaf3)

MORG:

121449835(Dnaaf3)

MFOT:

126493654 126496054

AAMP:

119821769(Dnaaf3)

NGI:	103744823(Dnaaf3)

HGL:	101711890(Dnaaf3)

CPOC:

100714373(Dnaaf3)

CCAN:

109696263(Dnaaf3)

DORD:

105999535(Dnaaf3)

DSP:	122110729(Dnaaf3)

PLOP:

125368139(Dnaaf3)

NCAR:

124966908

MMMA:

107158857(Dnaaf3)

OPI:	101532975(DNAAF3)

TUP:	102496539(DNAAF3)

GVR:	103594699(DNAAF3)

CFA:	484300(DNAAF3)

CLUD:

112645004(DNAAF3)

VVP:	112909343(DNAAF3)

VLG:	121484901(DNAAF3)

NPO:	129500664(DNAAF3)

AML:	100477166(DNAAF3)

UMR:	103680270(TNNI3)

UAH:

113247381

UAR:	123786948(TNNI3)

ELK:

111140064

LLV:

125089164

MPUF:

101676506(DNAAF3)

MNP:	132005521(DNAAF3)

MLK:	131818804(DNAAF3)

NVS:	122912185(DNAAF3)

ORO:	101373835(DNAAF3)

EJU:	114202064(DNAAF3)

ZCA:	113935896(DNAAF3)

MLX:	117997824(DNAAF3)

NSU:	110573687(DNAAF3)

LWW:	102727434(DNAAF3)

FCA:	123378923(DNAAF3)

PYU:	121023340(DNAAF3)

PBG:	122493742(DNAAF3)

PVIV:

125153307(DNAAF3)

LRUF:

124527754

PTG:	102964033(DNAAF3)

PPAD:

109259917(DNAAF3)

PUC:	125917310 125918194

AJU:

106980917

HHV:	120239759(DNAAF3)

BTA:	104968460(DNAAF3)

BOM:	102273536(DNAAF3)

BIU:	109572858(DNAAF3)

BBUB:

102413617(DNAAF3)

BBIS:

104995399(DNAAF3)

CHX:	102187159(DNAAF3)

OAS:	105602098(DNAAF3)

BTAX:

128063798(DNAAF3)

ODA:	120871918(DNAAF3)

CCAD:

122420140(DNAAF3)

MBEZ:

129545976(DNAAF3)

CFR:	102515021(DNAAF3)

CBAI:

105074355(DNAAF3)

CDK:	105098737(DNAAF3)

VPC:	102524749(DNAAF3)

BACU:

103008646(DNAAF3)

BMUS:

118885630(DNAAF3)

LVE:	103068401(DNAAF3)

OOR:	101269845(DNAAF3)

DLE:	111180990(DNAAF3)

PCAD:

102992089(DNAAF3)

PSIU:

116743789(DNAAF3)

NASI:

112406413(DNAAF3)

ECB:	100055404(DNAAF3)

EPZ:	103562863(DNAAF3)

EAI:	106840923(DNAAF3)

MYB:	102244705(DNAAF3)

MYD:	102759894(DNAAF3)

MMYO:

118655156(DNAAF3)

PKL:	118715918(DNAAF3)

EFUS:

103303377(DNAAF3)

MNA:	107541329(DNAAF3)

DRO:	112313758(DNAAF3)

SHON:

118981379(DNAAF3)

AJM:	119059945(DNAAF3)

PDIC:

114511404(DNAAF3)

PHAS:

123813360(DNAAF3)

MMF:	118638763(DNAAF3)

PPAM:

129082520(DNAAF3)

HAI:	109373750(DNAAF3)

RFQ:	117034317(DNAAF3)

PALE:

102889334(DNAAF3)

PGIG:

120598381(DNAAF3)

PVP:	105304921(DNAAF3)

RAY:	107515438(DNAAF3)

MJV:	108396326(DNAAF3)

TOD:	119248735(DNAAF3)

SARA:

101539092(DNAAF3)

SETR:

126027985(DNAAF3)

LAV:	100670413(DNAAF3)

TMU:

101361028

ETF:	101649248(DNAAF3)

DNM:	101415361(DNAAF3)

MDO:	100032905(DNAAF3)

GAS:	123255436 123255800

SHR:	100926748(DNAAF3)

AFZ:

127556699

PCW:	110220012(DNAAF3)

OAA:	100091418(DNAAF3)

PCOC:

116239622(DNAAF3)

CJO:	107307227(DNAAF3)

NMEL:

110391347

PMOA:

120512654(DNAAF3)

OTC:	121333032(DNAAF3)

ASN:	102377685(DNAAF3)

AMJ:	106736894(DNAAF3)

PSS:	102452734(DNAAF3)

CMY:	102940800(DNAAF3)

CCAY:

125627885(DNAAF3)

DCC:	119847261(DNAAF3)

CPIC:

101934386(DNAAF3)

CABI:

116840040(DNAAF3)

MRV:	120388272(DNAAF3)

ACS:	100561518(dnaaf3)

ASAO:

132779382(DNAAF3)

PVT:	110078591(DNAAF3)

SUND:

121934752(DNAAF3)

PBI:	103062903(DNAAF3)

PMUR:

107282484(DNAAF3)

CTIG:

120304514(DNAAF3)

TSR:	106538687 106538705(DNAAF3)

PGUT:

117669098(DNAAF3)

APRI:

131198714(DNAAF3)

PTEX:

113443605(DNAAF3)

NSS:	113418611(DNAAF3)

VKO:	123032091(DNAAF3)

PMUA:

114582357(DNAAF3)

PRAF:

128399903(DNAAF3)

ZVI:	118095054(DNAAF3)

HCG:	128329774(DNAAF3)

GJA:	107118433(DNAAF3)

STOW:

125445235(DNAAF3)

EMC:	129340153(DNAAF3)

XLA:	734905(dnaaf3.L)

XTR:	100493459(dnaaf3)

NPR:	108796751(DNAAF3)

RTEM:

120915352(DNAAF3)

BBUF:

121001376(DNAAF3)

BGAR:

122928653(DNAAF3)

MUO:	115465015(DNAAF3)

GSH:	117367383(DNAAF3)

DRE:	100148431(dnaaf3) 100536527(dnaaf3l)

SRX:

107736594

SANH:

107677178

SGH:

107599749

CCAR:

109107991(dnaaf3)

CAUA:

113092763(dnaaf3)

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

MASI:

TROS:

TDW:

MANU:

IPU:

IFU:

PHYP:

113533877(dnaaf3)

SMEO:

124384292

TFD:

113652100

TVC:	132846423(dnaaf3)

AMEX:

103035356(dnaaf3)

CMAO:

118822431(dnaaf3)

EEE:	113583383(dnaaf3)

CHAR:

105888794

TRU:	101063043(dnaaf3)

TFS:

130523910

TNG:	GSTEN00028279G001

LCO:	104935906(dnaaf3)

NCC:	104964176(dnaaf3)

TBEN:

117473963

CGOB:

115024522(dnaaf3)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:	116671250(dnaaf3)

PFLV:

114547929(dnaaf3)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

MSAM:

SCHU:

CUD:

ALAT:

ONL:	100701606(dnaaf3)

OAU:

116319866

OLA:	101157011(dnaaf3)

OML:

112154615

CSAI:

133419885

XMA:	102228076(dnaaf3)

XCO:	114136483(dnaaf3)

XHE:	116727666(dnaaf3)

PRET:

103481240(dnaaf3)

PFOR:

103132595(dnaaf3)

PLAI:

106937174(dnaaf3)

PMEI:

106910830(dnaaf3)

GAF:

122823595

PPRL:

129377895

CVG:	107097211 107101224

GMU:

124875483

NFU:	107387997(dnaaf3)

KMR:

108237062

ALIM:

106517434(dnaaf3)

NWH:

119423965

AOCE:

111584613(dnaaf3)

MCEP:

125022756

CSEM:

103382007

POV:	109626921(dnaaf3)

SSEN:

HHIP:

HSP:

SMAU:

LCF:

SDU:	111219791(dnaaf3)

SLAL:

111658635(dnaaf3)

XGL:

120794590

HCQ:	109523981(dnaaf3)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110159730(dnaaf3)

MALB:

109963636(dnaaf3)

BSPL:

114845558

SJO:

128381128

SASA:

106579171(dnaaf3)

STRU:

115160481(dnaaf3)

OTW:

112223749

OMY:

110491656

OGO:

124048401

ONE:	115106617(dnaaf3)

OKI:	109866025(dnaaf3)

OKE:

118363304

SALP:

111977422(dnaaf3)

SNH:

120045771

CCLU:

123484350

ELS:	105030667(dnaaf3)

SFM:	108925150(dnaaf3)

PKI:	111837266(dnaaf3)

AANG:

118217777

PSPA:

121305900

PSEX:

120542974

LCM:	102354046(DNAAF3)

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG17669(Dnaaf3)

DER:

6546930

DSE:

6609802

DSI:	Dsimw501_GD25389(Dsim_GD25389)

DYA:	Dyak_GE13909

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI19384

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119681525 119685491 119686378

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ011265

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:	105190455 112588851

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:	111415154 111423418

BMOR:

101737279 119631019

BMAN:

114248935

MSEX:

115442557

DPL:	KGM_206731

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:	111057203 120351766

HVI:

124366269

MQU:

129003433

PHU:	Phum_PHUM579660

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

PVM:

PCHN:

HAME:

PCLA:

PTRU:

EAF:	111700849 111711768

LSM:

TCF:

CSCU:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

HRO:	HELRODRAFT_163037

LGI:	LOTGIDRAFT_227827

PVUL:

PCAN:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_168710

SHX:	MS3_00008671(DNAAF3_1)

OVI:	T265_03788

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130644235 130646229

TAD:	TRIADDRAFT_52076

AQU:

100640711

VCN:	VOLCADRAFT_106739

MNG:

MNEG_1549

MIS:	MICPUN_113945(CS051)

MPP:	MICPUCDRAFT_70660(CS051)

MBR:	MONBRDRAFT_25830

SRE:	PTSG_10969

TGO:	TGME49_271315

TET:	TTHERM_00929510

PTM:	GSPATT00018036001

TPS:	THAPS_6875

PIF:	PITG_16795

PSOJ:

PHYSODRAFT_490132

SPAR:

SPRG_04133

GTT:	GUITHDRAFT_149705

TBR:	Tb11.47.0028

TBG:	TbgDal_XI1280

TCR:

511445.90

LMA:	LMJF_27_0590

LIF:	LINJ_27_2600

LMI:	LMXM_27_0590

LBZ:	LBRM_27_0700

LPAN:

LPMP_270580

» show all

Reference

PMID:22387996

Authors

Mitchison HM, Schmidts M, Loges NT, Freshour J, Dritsoula A, Hirst RA, O'Callaghan C, Blau H, Al Dabbagh M, Olbrich H, Beales PL, Yagi T, Mussaffi H, Chung EM, Omran H, Mitchell DR

Title

Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia.

Journal

Nat Genet 44:381-9, S1-2 (2012)
DOI:10.1038/ng.1106

Sequence

[hsa:352909]

All links

Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (2127)   
   KEGG GENES (562)   
   KEGG MGENES (98)   
   RefGene (1463)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (2132)   

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