KEGG   ORTHOLOGY: K21782
Entry
K21782                      KO                                     
Symbol
pigA, redW
Name
L-prolyl-PCP dehydrogenase [EC:1.3.8.14]
Pathway
map00333  Prodigiosin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Reaction
R06747  L-prolyl-[peptidyl-carrier protein]:electron-transfer flavoprotein oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21782  pigA, redW; L-prolyl-PCP dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.8  With a flavin as acceptor
    1.3.8.14  L-prolyl-[peptidyl-carrier protein] dehydrogenase
     K21782  pigA, redW; L-prolyl-PCP dehydrogenase
Other DBs
COG: COG1960
Genes
SMW: SMWW4_v1c11040(pigA)
SRR: SerAS9_1753
SRS: SerAS12_1753
SRA: SerAS13_1754
SERF: L085_23030
SERM: CLM71_22610
SSUR: ATE40_002235
SNEM: NLX84_05505
PROD: PCO85_04850
SERA: Ser39006_020695
VSR: Vspart_03968(pigA)
PSAZ: PA25_35580
SCO: SCO5879(redW)
STRD: NI25_09835
AG: CAH55629(pigA)
 » show all
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence

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