KEGG   ORTHOLOGY: K21989
Entry
K21989                      KO                                     

Name
TMEM63
Definition
calcium permeable stress-gated cation channel
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K21989  TMEM63; calcium permeable stress-gated cation channel
Transporters [BR:ko02000]
 Other transporters
  Pores ion channels
   K21989  TMEM63; calcium permeable stress-gated cation channel
Other DBs
GO: 0005227
TC: 1.A.17.5
Genes
HSA: 55362(TMEM63B) 57156(TMEM63C) 9725(TMEM63A)
PTR: 453066(TMEM63C) 457778(TMEM63A) 472016(TMEM63B)
PPS: 100977011(TMEM63B) 100982689(TMEM63C) 100995512(TMEM63A)
GGO: 101129730(TMEM63A) 101138476(TMEM63B) 101138672(TMEM63C)
PON: 100172079(TMEM63C) 100173184(TMEM63A) 100449141(TMEM63B)
NLE: 100592595(TMEM63A) 100600705(TMEM63B) 100605066(TMEM63C)
MCC: 701499(TMEM63A) 702797(TMEM63B) 707093(TMEM63C)
MCF: 102133207(TMEM63C) 102136331(TMEM63B) 102138789(TMEM63A)
CSAB: 103221440(TMEM63B) 103229384(TMEM63C) 103230004(TMEM63A)
RRO: 104667366(TMEM63B) 104677232(TMEM63A) 104677611(TMEM63C)
RBB: 108533449(TMEM63B) 108534955(TMEM63C) 108538732(TMEM63A)
CJC: 100402442(TMEM63A) 100402506(TMEM63C) 100406196(TMEM63B)
SBQ: 101027720(TMEM63C) 101032530(TMEM63A) 101039867(TMEM63B)
MMU: 208795(Tmem63a) 217733(Tmem63c) 224807(Tmem63b)
MCAL: 110284233(Tmem63b) 110289766(Tmem63a) 110307159(Tmem63c)
MPAH: 110321607(Tmem63a) 110324665(Tmem63c) 110335572(Tmem63b)
RNO: 289318(Tmem63a) 314332(Tmem63c) 363197(Tmem63b)
MUN: 110555838(Tmem63b) 110558289(Tmem63c) 110559912(Tmem63a)
CGE: 100751086(Tmem63a) 100758557(Tmem63b) 100765330(Tmem63c)
NGI: 103725111(Tmem63a) 103730770(Tmem63b) 103739637(Tmem63c)
HGL: 101697090(Tmem63a) 101703819(Tmem63b) 101705765 101706120 101707514(Tmem63c)
CCAN: 109682125(Tmem63b) 109691481(Tmem63a) 109697391(Tmem63c)
OCU: 100352435(TMEM63A) 100357518(TMEM63C) 100358268(TMEM63B)
TUP: 102486084(TMEM63C) 102494608(TMEM63B) 102494951(TMEM63A)
CFA: 490389(TMEM63A) 490804(TMEM63C) 609620(TMEM63B)
VVP: 112914030(TMEM63B) 112918302(TMEM63C) 112923562(TMEM63A)
AML: 100465436(TMEM63C) 100479615(TMEM63A) 100482731(TMEM63B)
UMR: 103664147(TMEM63B) 103669051(TMEM63A) 103674090(TMEM63C)
UAH: 113261250(TMEM63B) 113262913(TMEM63A) 113270297(TMEM63C)
ORO: 101368948(TMEM63B) 101375225(TMEM63A) 101385491(TMEM63C)
FCA: 101085772(TMEM63A) 101095338(TMEM63B) 101100895(TMEM63C)
PTG: 102949863(TMEM63A) 102956775(TMEM63B) 102969419(TMEM63C)
PPAD: 109250785(TMEM63A) 109253891 109271672(TMEM63B)
AJU: 106968618(TMEM63A) 106973957(TMEM63B) 106974348(TMEM63C)
BTA: 534017(TMEM63A) 534891(TMEM63B) 614000(TMEM63C)
BOM: 102267329(TMEM63A) 102278067(TMEM63B) 102284157(TMEM63C)
BIU: 109564577(TMEM63C) 109570426(TMEM63A) 109577006(TMEM63B)
BBUB: 102400621(TMEM63C) 102409065(TMEM63A) 102414847(TMEM63B)
CHX: 100861329(TMEM63B) 102169109(TMEM63C) 102188963(TMEM63A)
OAS: 101111305(TMEM63A) 101113242(TMEM63C) 101113706(TMEM63B)
SSC: 100151872(TMEM63B) 100523988(TMEM63A) 102158165(TMEM63C)
CFR: 102514906(TMEM63C) 102515879(TMEM63B) 102519175(TMEM63A)
CDK: 105086068(TMEM63C) 105088634(TMEM63B) 105099670(TMEM63A)
BACU: 103001323(TMEM63A) 103005281(TMEM63C) 103008997(TMEM63B)
LVE: 103073858(TMEM63A) 103089365(TMEM63C) 103091023(TMEM63B)
OOR: 101271058(TMEM63C) 101279289(TMEM63B) 101287895(TMEM63A)
DLE: 111176220(TMEM63C) 111177518(TMEM63A) 111178868(TMEM63B)
PCAD: 102980547(TMEM63C) 102983144(TMEM63B) 102985240(TMEM63A)
ECB: 100052069(TMEM63C) 100057436(TMEM63A) 100067695(TMEM63B)
EPZ: 103543506(TMEM63A) 103544353 103548175(TMEM63B) 103561832(TMEM63C)
EAI: 106828699(TMEM63B) 106830954(TMEM63C) 106844728(TMEM63A)
MYB: 102242352(TMEM63A) 102256147(TMEM63C) 102262955(TMEM63B)
MYD: 102766908(TMEM63A) 102770658(TMEM63C) 102772742(TMEM63B)
MNA: 107536898(TMEM63B) 107543001(TMEM63C) 107543642(TMEM63A)
HAI: 109381537(TMEM63C) 109382901(TMEM63B) 109391460(TMEM63A)
DRO: 112302116(TMEM63B) 112311705(TMEM63C) 112318920(TMEM63A)
PALE: 102883660(TMEM63A) 102889792(TMEM63B) 102895381(TMEM63C)
RAY: 107501970(TMEM63B) 107516681(TMEM63C) 107517096(TMEM63A)
MJV: 108389939(TMEM63C) 108407138(TMEM63B) 108408835(TMEM63A)
LAV: 100653639(TMEM63C) 100661107(TMEM63B) 100673476(TMEM63A)
MDO: 100012709(TMEM63B) 100022216(TMEM63C) 100025823(TMEM63A)
SHR: 100913686(TMEM63B) 100926659(TMEM63A) 100927809(TMEM63C)
PCW: 110205522(TMEM63A) 110208288(TMEM63C) 110213498(TMEM63B)
OAA: 100077070(TMEM63C) 100081979(TMEM63A) 100093605(TMEM63B)
GGA: 421319(TMEM63A) 423372(TMEM63C)
MGP: 100544487(TMEM63A) 100545884(TMEM63C) 100549918 104909642
CJO: 107311038(TMEM63A) 107311284(TMEM63B) 107315157(TMEM63C)
NMEL: 110395366(TMEM63B) 110395398(TMEM63A) 110401666(TMEM63C)
APLA: 101793276(TMEM63B) 101803040(TMEM63C) 101805379(TMEM63A)
ACYG: 106029745(TMEM63B) 106031587(TMEM63A) 106038872(TMEM63C)
TGU: 100220083(TMEM63A) 100220684(TMEM63B) 100221013(TMEM63C)
LSR: 110477246(TMEM63C) 110477504(TMEM63A) 110481714(TMEM63B)
SCAN: 103817871(TMEM63B) 103819289(TMEM63A) 103826510(TMEM63C)
GFR: 102035491(TMEM63B) 102041584(TMEM63A) 102044885(TMEM63C)
FAB: 101806741(TMEM63A) 101815911(TMEM63B) 101817990(TMEM63C)
PHI: 102099176(TMEM63B) 102100169(TMEM63C) 102113867(TMEM63A)
PMAJ: 107201816(TMEM63A) 107201845(TMEM63B) 107205784(TMEM63C)
CCAE: 111926270(TMEM63A) 111927558(TMEM63B) 111929943(TMEM63C)
CCW: 104684408(TMEM63B) 104685378(TMEM63C) 104685566(TMEM63A)
ETL: 114057422(TMEM63C) 114059343(TMEM63B) 114073695(TMEM63A)
FPG: 101913269(TMEM63B) 101914076(TMEM63C) 101914770(TMEM63A)
FCH: 102045692(TMEM63B) 102052543(TMEM63C) 102059636(TMEM63A)
CLV: 102085811(TMEM63A) 102089622(TMEM63C) 102093491(TMEM63B)
EGZ: 104132718(TMEM63B) 104133271(TMEM63C) 104134583(TMEM63A)
NNI: 104019294(TMEM63A) 104021005(TMEM63C) 104021519(TMEM63B)
ACUN: 113477835(TMEM63B) 113478627(TMEM63A) 113480587(TMEM63C)
PADL: 103913058(TMEM63C) 103922857(TMEM63B) 103925014(TMEM63A)
AAM: 106482714(TMEM63A) 106482888(TMEM63C) 106485505(TMEM63B)
ASN: 102367843(TMEM63B) 102368578(TMEM63A) 102374023(TMEM63C)
AMJ: 102569078(TMEM63C) 102577033(TMEM63A) 102577085(TMEM63B)
PSS: 102447931(TMEM63B) 102457864(TMEM63A) 102459462(TMEM63C)
CMY: 102934222(TMEM63A) 102939690(TMEM63B) 102942926(TMEM63C)
CPIC: 101935527(TMEM63A) 101945207(TMEM63C) 101952238(TMEM63B)
ACS: 100551518(tmem63b) 100555392(tmem63a) 100567302(tmem63c)
PVT: 110074687(TMEM63B) 110075378(TMEM63A) 110079365(TMEM63C)
PMUR: 107284549(TMEM63C) 107294459(TMEM63B) 107297028(TMEM63A) 107299460
TSR: 106542800(TMEM63A) 106546122(TMEM63B) 106547943(TMEM63C)
PMUA: 114591622(TMEM63C) 114594530(TMEM63B) 114594617(TMEM63A)
GJA: 107115265(TMEM63B) 107116466(TMEM63C) 107125544(TMEM63A)
XLA: 108698683(tmem63c.L) 108716486(tmem63a.L) 108716556(tmem63b.L) 108717638(tmem63b.S) 496016(tmem63a.S)
XTR: 100036641(tmem63c) 116410849(tmem63b) 779796(tmem63a)
NPR: 108801304(TMEM63A) 108802347
DRE: 100000800(tmem63c) 100334023(tmem63ba) 557924(tmem63a)
IPU: 108263178 108269493(tmem63c) 108271057 108279997(tmem63b)
PHYP: 113532045(tmem63b) 113536569 113538874(tmem63c) 113541947
AMEX: 103024235(tmem63b) 103030998
OLA: 101164362(tmem63c) 101164671 101164779 101167416(tmem63b)
NFU: 107375566 107378038(tmem63b) 107392371(tmem63c) 107394007(tmem63a)
KMR: 108228460 108234086(tmem63b) 108235961(tmem63c) 108247687
ALIM: 106515919(tmem63b) 106520041 106520796(tmem63c) 106529083
LCF: 108877118 108882278 108892587(tmem63c) 108896879(tmem63b)
SLAL: 111663211(tmem63c) 111669490 111672618(tmem63b) 111672894
BPEC: 110155456(tmem63c) 110162537 110172839
LCM: 102354730(TMEM63C) 102364041(TMEM63B)
RTP: 109913061
SPU: 580854
APLC: 110986312
SKO: 102806631
DME: Dmel_CG11210(Tmem63)
DER: 6541529
DSE: 6608113
DSI: Dsimw501_GD10542(Dsim_GD10542)
DAN: 6496499
DSR: 110191122
DPE: 6592769
DWI: 6652414
DAZ: 108615731
DNV: 108654882
DHE: 111600643
DVI: 6627177
MDE: 101894742
LCQ: 111685055
AAG: 5573309
AALB: 109416353
AME: 409310
BIM: 100743565
BTER: 100649774
CCAL: 108627790
OBB: 114878392
SOC: 105200332
MPHA: 105831459
AEC: 105142909
ACEP: 105621317
PBAR: 105428968
VEM: 105569920
HST: 105182265
DQU: 106747322
CFO: 105253792
PGC: 109859546
OBO: 105288018
PCF: 106783992
NVI: 100116180
CSOL: 105366294
MDL: 103578917
TCA: 658156
DPA: 109540968
ATD: 109598072
NVL: 108563627
BMOR: 101738431
BMAN: 114250689
PMAC: 106716033
PRAP: 110993685
HAW: 110381209
TNL: 113502128
API: 100161550
DNX: 107163189
AGS: 114121943
RMD: 113558738
BTAB: 109038127
ZNE: 110835526
FCD: 110844328
PVM: 113807872
TUT: 107364434
DPTE: 113791056
CSCU: 111621133
PCAN: 112570879
CRG: 105341349
MYI: 110462804
SHX: MS3_06853
EPA: 110243669
AQU: 100633972
LJA: Lj0g3v0286499.1(Lj0g3v0286499.1) Lj0g3v0304059.1(Lj0g3v0304059.1) Lj1g3v1781090.2(Lj1g3v1781090.2) Lj2g3v1068720.1(Lj2g3v1068720.1) Lj2g3v1277460.1(Lj2g3v1277460.1) Lj2g3v1277460.2(Lj2g3v1277460.2) Lj2g3v1536260.1(Lj2g3v1536260.1) Lj2g3v1536260.2(Lj2g3v1536260.2) Lj2g3v2904940.1(Lj2g3v2904940.1) Lj4g3v0684100.1(Lj4g3v0684100.1) Lj4g3v0684100.2(Lj4g3v0684100.2) Lj6g3v1948640.1(Lj6g3v1948640.1) Lj6g3v1948640.2(Lj6g3v1948640.2)
DOSA: Os01t0534900-01(Os01g0534900) Os01t0950900-01(Os01g0950900) Os03t0726300-01(Os03g0726300) Os05t0393800-01(Os05g0393800) Os05t0594700-01(Os05g0594700) Os07t0150100-01(Os07g0150100) Os10t0579100-01(Os10g0579100) Os12t0582800-01(Os12g0582800) Os12t0633600-01(Os12g0633600)
ATS: 109732801(LOC109732801) 109733205(LOC109733205) 109733206(LOC109733206) 109734659(LOC109734659) 109742461(LOC109742461) 109744917(LOC109744917) 109746981(LOC109746981) 109748530(LOC109748530) 109757321(LOC109757321) 109759807(LOC109759807) 109768880(LOC109768880) 109776561(LOC109776561) 109781624(LOC109781624) 109782385(LOC109782385) 109784644(LOC109784644) 109787162(LOC109787162)
SCE: YLL005C(SPO75) YLR241W(CSC1) YMR266W(RSN1) YOL084W(PHM7)
KMX: KLMA_20063(RSN1) KLMA_30232(SPO75) KLMA_30396(PHM7) KLMA_50574
NCS: NCAS_0A01520(NCAS0A01520) NCAS_0B05380(NCAS0B05380) NCAS_0C00540(NCAS0C00540) NCAS_0C02840(NCAS0C02840)
NDI: NDAI_0B02790(NDAI0B02790) NDAI_0C02460(NDAI0C02460) NDAI_0G02170(NDAI0G02170) NDAI_0K00540(NDAI0K00540)
TPF: TPHA_0A00770(TPHA0A00770) TPHA_0E03010(TPHA0E03010) TPHA_0I00440(TPHA0I00440) TPHA_0L00950(TPHA0L00950)
TBL: TBLA_0B03100(TBLA0B03100) TBLA_0C03660(TBLA0C03660) TBLA_0H03230(TBLA0H03230)
TDL: TDEL_0B00780(TDEL0B00780) TDEL_0D05040(TDEL0D05040) TDEL_0E04180(TDEL0E04180) TDEL_0F05240(TDEL0F05240)
KAF: KAFR_0B03710(KAFR0B03710) KAFR_0C01290(KAFR0C01290) KAFR_0C06410(KAFR0C06410) KAFR_0H01900(KAFR0H01900)
CAL: CAALFM_C106270WA(CaO19.1823) CAALFM_C109430WA(CaO19.4805) CAALFM_C208140CA(PHM7) CAALFM_C304720CA(CaO19.5932) CAALFM_C403670WA(SPO75)
NTE: NEUTE1DRAFT120980(NEUTE1DRAFT_120980) NEUTE1DRAFT132786(NEUTE1DRAFT_132786) NEUTE1DRAFT144926(NEUTE1DRAFT_144926) NEUTE1DRAFT80098(NEUTE1DRAFT_80098) NEUTE1DRAFT82913(NEUTE1DRAFT_82913)
ANG: ANI_1_1036024(An02g07460) ANI_1_1376124(An14g03660) ANI_1_1486144(An16g01540) ANI_1_602104(An12g04730)
ABP: AGABI1DRAFT115312(AGABI1DRAFT_115312) AGABI1DRAFT120878(AGABI1DRAFT_120878) AGABI1DRAFT124299(AGABI1DRAFT_124299) AGABI1DRAFT19567(AGABI1DRAFT_19567) AGABI1DRAFT71333(AGABI1DRAFT_71333) AGABI1DRAFT77228(AGABI1DRAFT_77228)
ABV: AGABI2DRAFT117833(AGABI2DRAFT_117833) AGABI2DRAFT147596(AGABI2DRAFT_147596) AGABI2DRAFT207398(AGABI2DRAFT_207398) AGABI2DRAFT210827(AGABI2DRAFT_210827) AGABI2DRAFT225252(AGABI2DRAFT_225252) AGABI2DRAFT48387(AGABI2DRAFT_48387)
 » show all
Reference
  Authors
Zhao X, Yan X, Liu Y, Zhang P, Ni X
  Title
Co-expression of mouse TMEM63A, TMEM63B and TMEM63C confers hyperosmolarity activated ion currents in HEK293 cells.
  Journal
Cell Biochem Funct 34:238-41 (2016)
DOI:10.1002/cbf.3185
  Sequence
Reference
  Authors
Hou C, Tian W, Kleist T, He K, Garcia V, Bai F, Hao Y, Luan S, Li L
  Title
DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes.
  Journal
Cell Res 24:632-5 (2014)
DOI:10.1038/cr.2014.14
  Sequence
[hsa:57156] [ath:AT4G22120] [sce:YLR241W]

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