KEGG   ORTHOLOGY: K23353
Entry
K23353                      KO                                     

Name
PDLIM1_2_3_4
Definition
PDZ and LIM domain protein 1/2/3/4
Disease
H01593  Osteoporosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K23353  PDLIM1_2_3_4; PDZ and LIM domain protein 1/2/3/4
Domain-containing proteins not elsewhere classified [BR:ko04990]
 LIM domain-containing proteins
  PDZ-LIM family proteins
   K23353  PDLIM1_2_3_4; PDZ and LIM domain protein 1/2/3/4
Genes
HSA: 27295(PDLIM3) 64236(PDLIM2) 8572(PDLIM4) 9124(PDLIM1)
PTR: 450627(PDLIM1) 461639(PDLIM3) 462048(PDLIM4) 464045(PDLIM2)
PPS: 100968884(PDLIM1) 100975474(PDLIM2) 100981687(PDLIM3) 100994921(PDLIM4)
GGO: 101128976(PDLIM1) 101134689(PDLIM4) 101135985(PDLIM3) 101137017(PDLIM2) 115932913
PON: 100442019(PDLIM3) 100447796(PDLIM4) 100450138(PDLIM1) 100457098(PDLIM2)
NLE: 100592120(PDLIM3) 100595799(PDLIM4) 100600075(PDLIM2) 100603473(PDLIM1)
MCC: 695779(PDLIM3) 702998(PDLIM1) 707372(PDLIM4) 708652(PDLIM2)
MCF: 102120772(PDLIM4) 102120838(PDLIM1) 102126589(PDLIM2) 102130112(PDLIM3)
CSAB: 103215454(PDLIM2) 103216305(PDLIM1) 103229895 103236630(PDLIM3) 103244506(PDLIM4)
RRO: 104659845(PDLIM4) 104663971(PDLIM2) 104664672(PDLIM1) 104673809(PDLIM3)
RBB: 108522416(PDLIM3) 108529596(PDLIM4) 108540783(PDLIM2) 108543805(PDLIM1)
CJC: 100385747(PDLIM2) 100393707(PDLIM1) 100409448(PDLIM4) 100414115(PDLIM3)
SBQ: 101039646(PDLIM1) 101041466(PDLIM4) 101042628(PDLIM2) 101050781(PDLIM3)
MMU: 213019(Pdlim2) 30794(Pdlim4) 53318(Pdlim3) 54132(Pdlim1)
MCAL: 110285559(Pdlim1) 110300181(Pdlim3) 110305754(Pdlim4) 110309338(Pdlim2)
MPAH: 110325843(Pdlim2) 110327176(Pdlim1) 110332266(Pdlim4) 110336516(Pdlim3)
RNO: 114108(Pdlim3) 24915(Pdlim4) 290354(Pdlim2) 54133(Pdlim1)
MUN: 110546326(Pdlim1) 110548773(Pdlim4) 110551680(Pdlim2) 110562293(Pdlim3)
CGE: 100756459(Pdlim1) 100762311(Pdlim4) 100768674(Pdlim2) 100770287(Pdlim3)
NGI: 103733225(Pdlim1) 103747043(Pdlim4) 103747904(Pdlim2) 103750488(Pdlim3)
HGL: 101711555(Pdlim3) 101712207(Pdlim1) 101721824(Pdlim2) 101723285(Pdlim4)
CCAN: 109681775(Pdlim2) 109693651(Pdlim1) 109695372(Pdlim3) 109696564(Pdlim4)
OCU: 100328722(PDLIM4) 100343541(PDLIM3) 100352283(PDLIM1) 100353069(PDLIM2)
TUP: 102481311(PDLIM2) 102482595(PDLIM3) 102497117(PDLIM4) 102498737(PDLIM1)
CFA: 477779(PDLIM1) 480944 481498(PDLIM4) 482907(PDLIM3) 486123(PDLIM2)
VVP: 112914040(PDLIM1) 112917088(PDLIM4) 112926817(PDLIM2) 112934752(PDLIM3)
AML: 100469355(PDLIM3) 100469961(PDLIM1) 100471834(PDLIM2) 100481220(PDLIM4)
UMR: 103658760(PDLIM1) 103663969(PDLIM4) 103673341(PDLIM2) 103680977(PDLIM3)
UAH: 113251752(PDLIM1) 113261707(PDLIM4) 113262276(PDLIM3) 113269998(PDLIM2)
ORO: 101375224(PDLIM3) 101382061(PDLIM4) 101384221(PDLIM1) 101385795(PDLIM2)
ELK: 111140981 111144438 111144915 111156705
FCA: 101087474(PDLIM2) 101092600(PDLIM3) 101094980(PDLIM4) 101095859(PDLIM1)
PTG: 102949099(PDLIM3) 102950082(PDLIM1) 102950837(PDLIM2) 102956009(PDLIM4)
PPAD: 109250895(PDLIM4) 109251001(PDLIM3) 109264685(PDLIM1) 109277347(PDLIM2)
AJU: 106970714(PDLIM4) 106981109(PDLIM2) 106982216(PDLIM3) 106984800(PDLIM1)
BTA: 512907(PDLIM2) 515410(PDLIM4) 538516(PDLIM3) 614675(PDLIM1)
BOM: 102268547(PDLIM1) 102274911(PDLIM4) 102283741(PDLIM3) 102287712(PDLIM2)
BIU: 109553046(PDLIM1) 109553307(PDLIM3) 109561820(PDLIM4) 109563109(PDLIM2)
BBUB: 102389917(PDLIM1) 102400246(PDLIM3) 102412777(PDLIM4) 102414642(PDLIM2)
CHX: 100861269(PDLIM3) 102172031(PDLIM1) 102180314(PDLIM2) 102181769(PDLIM4)
OAS: 101102144(PDLIM4) 101107916(PDLIM1) 101113652(PDLIM3) 101114752(PDLIM2)
SSC: 100155592(PDLIM1) 100520235(PDLIM4) 100737811(PDLIM2) 414421(PDLIM3)
CFR: 102506912(PDLIM4) 102509640(PDLIM3) 102512710 102515068(PDLIM2) 102522423(PDLIM1)
CDK: 105084255(PDLIM1) 105084446(PDLIM3) 105090063(PDLIM4) 105100047 105102622(PDLIM2)
BACU: 103001825(PDLIM3) 103005389(PDLIM4) 103007312(PDLIM2) 103018508(PDLIM1)
LVE: 103071819(PDLIM2) 103078137(PDLIM3) 103083202(PDLIM1) 103089978(PDLIM4)
OOR: 101272177(PDLIM2) 101282464(PDLIM1) 101285740(PDLIM3) 101288005(PDLIM4)
DLE: 111169003(PDLIM2) 111172469(PDLIM1) 111173422(PDLIM3) 111182409(PDLIM4)
PCAD: 102973903(PDLIM2) 102976637(PDLIM3) 102981786 102982137(PDLIM4) 102988155(PDLIM1)
ECB: 100053879(PDLIM2) 100057090(PDLIM3) 100061326(PDLIM1) 100072879(PDLIM4)
EPZ: 103552769(PDLIM2) 103555430(PDLIM1) 103561532(PDLIM3) 103563280(PDLIM4)
EAI: 106840376(PDLIM3) 106841023(PDLIM4) 106842114(PDLIM1) 106847706(PDLIM2)
MYB: 102240002(PDLIM1) 102242435(PDLIM4) 102248311(PDLIM3) 102255169(PDLIM2)
MYD: 102753203(PDLIM2) 102764401(PDLIM3) 102770148(PDLIM1) 102774845(PDLIM4)
MNA: 107525051(PDLIM4) 107535750(PDLIM3) 107536090(PDLIM2) 107542663(PDLIM1)
HAI: 109375964(PDLIM2) 109380971(PDLIM1) 109382602(PDLIM4) 109395844(PDLIM3)
DRO: 112305179(PDLIM2) 112306722(PDLIM3) 112307082(PDLIM1) 112318117(PDLIM4)
PALE: 102877780(PDLIM2) 102880354(PDLIM3) 102891672(PDLIM1) 102892049(PDLIM4)
RAY: 107497061(PDLIM4) 107509225(PDLIM2) 107510441(PDLIM3) 107520432(PDLIM1)
MJV: 108385550(PDLIM3) 108386794(PDLIM1) 108389876 108393198(PDLIM2)
LAV: 100664553(PDLIM2) 100673962(PDLIM3) 100675370(PDLIM1) 100676465(PDLIM4)
TMU: 101347307 101347936 101355981 101356825
MDO: 100011638(PDLIM3) 100017547(PDLIM1) 100018463(PDLIM4) 100033108(PDLIM2)
SHR: 100914164(PDLIM4) 100915820(PDLIM2) 100916144(PDLIM3) 100933514(PDLIM1)
PCW: 110200428(PDLIM2) 110211703(PDLIM4) 110215415(PDLIM1) 110222583(PDLIM3)
OAA: 100074342(PDLIM1) 100079271(PDLIM4) 100085321(PDLIM3) 100087517(PDLIM2)
GGA: 395643(PDLIM4) 414873(PDLIM3) 428948(PDLIM1)
MGP: 100544138(PDLIM1) 100548391(PDLIM3) 100549229(PDLIM4)
CJO: 107313640(PDLIM3) 107315822(PDLIM1) 107320085(PDLIM4)
NMEL: 110398867(PDLIM3) 110399492(PDLIM1) 110405404(PDLIM4)
APLA: 101790955(PDLIM3) 101792194(PDLIM4) 101800302(PDLIM1)
ACYG: 106030501(PDLIM1) 106032666(PDLIM4) 106035154(PDLIM3)
TGU: 100219298(PDLIM1) 100219327(PDLIM3) 100223863(PDLIM4) 115498102(PDLIM2)
LSR: 110476449(PDLIM3) 110479422(PDLIM2) 110480344(PDLIM1) 110481055(PDLIM4)
SCAN: 103813980(PDLIM1) 103817244(PDLIM4) 103825520(PDLIM3) 108964450(PDLIM2) 115483872
GFR: 102034376(PDLIM3) 102036916(PDLIM1) 102037423(PDLIM4)
FAB: 101811062(PDLIM3) 101813326(PDLIM4) 101814290(PDLIM1)
PHI: 102100383(PDLIM2) 102106354(PDLIM3) 102106924(PDLIM1) 102113374(PDLIM4)
PMAJ: 107203456(PDLIM3) 107206633(PDLIM1) 107210732(PDLIM4) 107213964(PDLIM2)
CCAE: 111927966(PDLIM3) 111931091(PDLIM1) 111935408 111944393 111944715
CCW: 104690584(PDLIM3) 104697116(PDLIM1) 104697983(PDLIM4)
ETL: 114055567(PDLIM3) 114065364(PDLIM1) 114065709(PDLIM4) 114070080(PDLIM2)
FPG: 101913284(PDLIM4) 101913580(PDLIM1) 101914961(PDLIM3) 101917152(PDLIM2)
FCH: 102047560(PDLIM1) 102047913(PDLIM4) 102052484(PDLIM2) 102055983(PDLIM3)
CLV: 102091602(PDLIM3) 102093874(PDLIM2) 102095745(PDLIM1) 102097213(PDLIM4)
EGZ: 104129117(PDLIM1) 104129479(PDLIM3) 104133529(PDLIM4)
NNI: 104012011(PDLIM4) 104018578(PDLIM1) 104019546(PDLIM2) 104021295(PDLIM3)
ACUN: 113479313(PDLIM3) 113481639(PDLIM1) 113485361(PDLIM4)
PADL: 103915569(PDLIM1) 103915799(PDLIM4) 103922520(PDLIM3)
AAM: 106484037(PDLIM3) 106487238(PDLIM4) 106498875
ASN: 102373408(PDLIM2) 102375608(PDLIM4) 102376330(PDLIM1) 102387487(PDLIM3)
AMJ: 102562626(PDLIM4) 102572540(PDLIM1) 102574635(PDLIM3) 106738393(PDLIM2)
PSS: 102445031(PDLIM2) 102452164(PDLIM4) 102453792 102456890(PDLIM3)
CMY: 102931657(PDLIM1) 102933393(PDLIM4) 102940242(PDLIM3) 102944914(PDLIM2)
CPIC: 101931609(PDLIM3) 101933941(PDLIM4) 101941432(PDLIM2) 101944960(PDLIM1)
ACS: 100561175(pdlim3) 100566508(pdlim1) 100567250(pdlim4) 103280612(pdlim2)
PVT: 110072177(PDLIM2) 110083703(PDLIM3) 110086686(PDLIM4) 110087247(PDLIM1)
PBI: 103059831(PDLIM4) 103061815(PDLIM2) 103065298(PDLIM3)
PMUR: 107289240(PDLIM2) 107297048 107302662(PDLIM3)
TSR: 106548775(PDLIM3) 106551956(PDLIM2) 106554166(PDLIM4)
PMUA: 114585420(PDLIM2) 114591256(PDLIM4) 114596992(PDLIM1) 114604631(PDLIM3)
GJA: 107108755(PDLIM4) 107112996(PDLIM2) 107114892 107116728(PDLIM3)
XLA: 108706616 108713278 398461(pdlim1.S) 398648(pdlim1.L) 444755(pdlim3.S) 446969(pdlim4.L)
XTR: 100488396(pdlim2) 394527(pdlim1) 394862(pdlim4) 448291(pdlim3)
NPR: 108790925(PDLIM3) 108792822(PDLIM2) 108792896(PDLIM4) 108793502(PDLIM1)
DRE: 550568(pdlim1) 554148(pdlim3a) 560322(pdlim2) 561865(pdlim3b) 569404(pdlim4)
SRX: 107707216 107715983 107724143 107726967 107740981 107742424(pdlim4) 107743498 107746050 107751927 107754177 107758671
SANH: 107655446 107656980 107658037 107661708 107666525 107670171 107683893 107689893 107702342 107702839 107703091
SGH: 107548241 107558198(pdlim3) 107559336 107562166(pdlim4) 107565117 107577659 107581970 107600156 107601889
CCAR: 109044887 109046118(pdlim4) 109046120 109064247 109078947 109085979 109087399 109096650 109098153 109101452 109106242
IPU: 100528277(pdli3) 108263746(pdlim1) 108265771(Pdlim2) 108268957
PHYP: 113529227(pdlim3) 113533378 113545477(pdlim1) 113547329
AMEX: 103022934 103027512(pdlim1) 103035000 103042722 111191484 111197428
EEE: 113578028(pdlim4) 113585234(pdlim1) 113586704 113590587 113591057(pdlim3)
TRU: 101064372 101069356(pdlim1) 101076293(pdlim3) 101079609(pdlim4)
TNG: GSTEN00013687G001 GSTEN00024532G001 GSTEN00026658G001
LCO: 104917816(pdlim3) 104921833 104921897(pdlim1) 104931725(pdlim4)
NCC: 104940826 104952736(pdlim1) 104962399(pdlim4) 104963286 104965743(pdlim3)
MZE: 101474034(pdlim1) 101484652(pdlim3) 101487038 101487684(pdlim4)
ONL: 100702294 100702631(pdlim4) 100703143(pdlim1) 100704170(pdlim3)
OLA: 101156764(pdlim1) 101158506(pdlim3) 101166681(pdlim4) 101171087(pdlim2)
XMA: 102220104(pdlim4) 102225150(pdlim1) 102232818 102237719(pdlim3)
XCO: 114138395(pdlim1) 114144135(pdlim3) 114153098(pdlim4) 114154646
PRET: 103461896(pdlim3) 103470528 103475339(pdlim4) 103477121(pdlim1)
CVG: 107082318 107088745(pdlim1) 107094914(pdlim3) 107104942(pdlim4)
NFU: 107375560(pdlim1) 107386794(pdlim4) 107388434 107393736(pdlim2) 107397062
KMR: 108230125 108236585(pdlim2) 108238878(pdlim4) 108240626(pdlim1)
ALIM: 106519685(pdlim3) 106520157(pdlim2) 106525529(pdlim4) 106525609(pdlim1)
AOCE: 111563923 111573103(pdlim1) 111582155 111582917(pdlim3)
CSEM: 103383310(pdlim3) 103387464(pdlim1) 103395275(pdlim4) 103398141
POV: 109633588 109635850(pdlim1) 109635889(pdlim4) 109641899(pdlim3)
LCF: 108878339 108886256(pdlim1) 108893783(pdlim4) 108901656(pdlim3)
SDU: 111216633(pdlim3) 111220736(pdlim1) 111228592 111234474(pdlim4)
SLAL: 111645061 111663286(pdlim3) 111669555(pdlim1) 111672106(pdlim4)
HCQ: 109509743(pdlim4) 109511388(pdlim3) 109523100(pdlim1) 109524979(pdlim2)
BPEC: 110153975(pdlim4) 110162109(pdlim1) 110166203(pdlim3) 110169853(pdlim2)
MALB: 109954975(pdlim2) 109959994(pdlim4) 109962279(pdlim1) 109968195(pdlim3)
SASA: 100136395(alp) 100194774(pdli2) 100195193(pdli1) 100195616(pdli3) 100196889(pdli4) 106567515 106579838(PDLI2) 106604587 106612021(pdlim3)
OTW: 112228327 112231592 112248480 112249749 112252805(pdlim1) 112255986(pdlim3) 112258103 112258244 112261388 112262918
SALP: 111950626 111951836 111957870 111958510 111971624 111974595 111978333 111981560
ELS: 105014251(pdlim2) 105022863 105026670(pdlim3) 105028256(pdlim4) 105028652(pdlim1)
SFM: 108923634 108924559(pdlim3) 108929522 108929650 108932876(pdlim1) 108934460(pdlim4)
PKI: 111833421 111838304 111839543(pdlim4) 111853625(pdlim3) 111857301 111860128(pdlim1)
LCM: 102345972(PDLIM4) 102364746(PDLIM3) 102364867(PDLIM2) 102367049(PDLIM1)
CMK: 103178202(pdlim3) 103183669(pdlim4) 103185829 103187761(pdlim2)
RTP: 109912877(pdlim3) 109918571 109920840 109920984
BFO: 118408732 118409879 118415165
CIN: 100184646 100186497
SPU: 100893866
SKO: 102801031
AME: 726668
BIM: 100741711
BTER: 100646793
CCAL: 108626208
OBB: 114877359
SOC: 105202657
MPHA: 105838116
AEC: 105153479
ACEP: 105619704
PBAR: 105425262
VEM: 105564874
HST: 105191715
DQU: 106747137
CFO: 105252580
LHU: 105668327
PGC: 109851915
OBO: 105275507
PCF: 106792080
NVI: 100123487(Zasp66)
CSOL: 105362855
MDL: 103568705
DPA: 109537366
NVL: 108556409
BMOR: 101737298
BMAN: 114250789
DPL: KGM_202458
PMAC: 106714993
PRAP: 110998372
PXY: 105395010
DNX: 107162779
AGS: 114129056 114131867
BTAB: 109041194
CLEC: 106666321
PTEP: 107453646
CBR: CBG12470 CBG24240
NAI: NECAME_15536
LGI: LOTGIDRAFT_95036
SMM: Smp_022340
SHX: MS3_03091
OVI: T265_12695
EGL: EGR_02856 EGR_02857
 » show all
Reference
PMID:9573374
  Authors
Bashirova AA, Markelov ML, Shlykova TV, Levshenkova EV, Alibaeva RA, Frolova EI
  Title
The human RIL gene: mapping to human chromosome 5q31.1, genomic organization and alternative transcripts.
  Journal
Gene 210:239-45 (1998)
DOI:10.1016/S0378-1119(98)00080-8
  Sequence
[hsa:8572]
Reference
PMID:9334352
  Authors
Xia H, Winokur ST, Kuo WL, Altherr MR, Bredt DS
  Title
Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs.
  Journal
J Cell Biol 139:507-15 (1997)
DOI:10.1083/jcb.139.2.507
  Sequence
[hsa:27295]
Reference
  Authors
Loughran G, Healy NC, Kiely PA, Huigsloot M, Kedersha NL, O'Connor R
  Title
Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent  growth.
  Journal
Mol Biol Cell 16:1811-22 (2005)
DOI:10.1091/mbc.e04-12-1052
  Sequence
[hsa:64236]
Reference
  Authors
Bauer K, Kratzer M, Otte M, de Quintana KL, Hagmann J, Arnold GJ, Eckerskorn C, Lottspeich F, Siess W
  Title
Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells.
  Journal
Blood 96:4236-45 (2000)
  Sequence
[hsa:9124]

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