KEGG   ORTHOLOGY: K23493
Entry
K23493            Tight     KO                                     

Name
GS
Definition
geissoschizine synthase [EC:1.3.1.36]
Pathway
ko00901  Indole alkaloid biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K23493  GS; geissoschizine synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.36  geissoschizine dehydrogenase
     K23493  GS; geissoschizine synthase
Other DBs
RN: R03860
GO: 0047920
Genes
AG: AHK60845(GS2) AHK60846(GS1)
Reference
  Authors
Miettinen K, Dong L, Navrot N, Schneider T, Burlat V, Pollier J, Woittiez L, van der Krol S, Lugan R, Ilc T, Verpoorte R, Oksman-Caldentey KM, Martinoia E, Bouwmeester H, Goossens A, Memelink J, Werck-Reichhart D
  Title
The seco-iridoid pathway from Catharanthus roseus.
  Journal
Nat Commun 5:3606 (2014)
DOI:10.1038/ncomms4606
  Sequence
Reference
  Authors
Tatsis EC, Carqueijeiro I, Duge de Bernonville T, Franke J, Dang TT, Oudin A, Lanoue A, Lafontaine F, Stavrinides AK, Clastre M, Courdavault V, O'Connor SE
  Title
A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate.
  Journal
Nat Commun 8:316 (2017)
DOI:10.1038/s41467-017-00154-x
  Sequence

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