KEGG   ORTHOLOGY: K24566
Entry
K24566                      KO                                     
Symbol
oleAIII
Name
8,8a-deoxyoleandolide synthase 3
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Reaction
R06453  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K24566  oleAIII; 8,8a-deoxyoleandolide synthase 3
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K24566  oleAIII; 8,8a-deoxyoleandolide synthase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K24566  oleAIII; 8,8a-deoxyoleandolide synthase 3
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Oleandomycin synthase
     K24566  oleAIII; 8,8a-deoxyoleandolide synthase 3
Genes
AG: AAA19695(oleAIII)
Reference
PMID:10908114
  Authors
Shah S, Xue Q, Tang L, Carney JR, Betlach M, McDaniel R
  Title
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.
  Journal
J Antibiot (Tokyo) 53:502-8 (2000)
DOI:10.7164/antibiotics.53.502
Reference
PMID:8107683
  Authors
Swan DG, Rodriguez AM, Vilches C, Mendez C, Salas JA
  Title
Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence.
  Journal
Mol Gen Genet 242:358-62 (1994)
DOI:10.1007/BF00280426
  Sequence
[ag:AAA19695]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (8)   
   KEGG REACTION (1)   
   KEGG RCLASS (7)   
Gene (1)   
   KEGG GENES (1)   
All databases (18)   

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