KEGG   Klebsiella michiganensis E718: A225_0101
Entry
A225_0101         CDS       T02173                                 
Name
(GenBank) Aspartokinase
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
koe  Klebsiella michiganensis E718
Pathway
koe00260  Glycine, serine and threonine metabolism
koe00261  Monobactam biosynthesis
koe00270  Cysteine and methionine metabolism
koe00300  Lysine biosynthesis
koe01100  Metabolic pathways
koe01110  Biosynthesis of secondary metabolites
koe01120  Microbial metabolism in diverse environments
koe01230  Biosynthesis of amino acids
Module
koe_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
koe_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
koe_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:koe00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    A225_0101
   00270 Cysteine and methionine metabolism
    A225_0101
   00300 Lysine biosynthesis
    A225_0101
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    A225_0101
Enzymes [BR:koe01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     A225_0101
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     A225_0101
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3
Other DBs
NCBI-ProteinID: AFN30058
Position
104505..106937
AA seq 810 aa
MSVIAQAGAKGRQLHKFGGSSLADAKCYLRVAGIMTEYSQAGDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQSLRRYQMELISGLLSPDAADTLIAIFIQDLERLAGLLDGGVTDA
VYAEVVGHGEVWSARLMAAVLNHLGVEAAWLDARSFLRAERSAQPQVDEGLSYPLLQQLI
AQHPNKRLVVTGFISRNNAGETVLLGRNGSDYSATQIGALAGASRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDVCLIEFQVPGGQDFKLAHKELDAILKRAQLRPLAVGVHADRKLL
QFCYTSEVADSALKLLDEAGLPGELRLRQKLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRAGPTESLIQGLHQSLFRAEKRIGLVLFGKGNIGSRWLELFARE
QTTLSARTGFEFILAGVVDSRRSLLNYEGLDASRALAFFNDEAVEQDEESLFLWMCAHPY
DDLVVLDVTASAQLADQYLDFASHGFHVISANKLAGASSSSKYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLIDSGDTILALSGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEEGSVDHFFENGEALNE
QMLQRLEAAREMGLVLRYVARFDANGKARVGVEAVREEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq 2433 nt   +upstreamnt  +downstreamnt
atgagtgtgattgcgcaggcaggggcgaagggtcgtcagctgcacaaatttggtgggagt
agtttagcggatgcgaaatgttacctgcgcgtcgcgggtattatgacggagtattcgcag
gcgggcgacatgatggtcgtctctgccgccggcagtaccaccaaccagttgatcagctgg
ctgaagctcagccagaccgatcgcctttctgcgcatcaggtgcaacaatcgctccgtcgt
tatcagatggagctcatctccggactgctgtcaccagacgctgccgacacgctgattgcc
atctttattcaggatcttgagcgccttgccgggttgcttgacggcggcgtcaccgacgcg
gtatacgccgaagtcgtcggtcacggcgaagtctggtcggcccgcctgatggcggcggtg
ctgaaccatcttggcgtagaagccgcctggctggatgcgcgtagcttcctgcgcgccgag
cgctccgcgcagccgcaggtggatgaaggtttatcctatccgcttttgcagcagctgata
gcgcagcacccgaacaagcgtctggtggtgaccggctttatttcgcgtaacaacgccggg
gaaaccgtcctgctggggcgtaacggttccgactattccgccacccaaatcggcgccctg
gccggggcgtctcgcgtcactatctggagcgacgtggccggggtctacagcgcggatccg
cgtaaagtgaaagacgcctgtctgctgccgctgctgcgcctggatgaagccagcgaactg
gcccgcctggcggcgccggtgctgcatgcccgtacgctgcagccggtctccggcagcgat
atcgatttacaattacgctgtagctacaccccggatcagggctcaacgcgcatcgaacgc
gtgctggcttccggtaccggggcgcgtatcgtgaccagccatgatgatgtctgcctgatt
gagttccaggtacccggcggccaggatttcaaactggcgcataaagagctggacgctatc
ttaaaacgcgcccagctgcgtccgctggcggttggcgtacacgccgaccgtaagctgctg
cagttctgctacacctctgaagtggccgacagcgcgctgaagctgctggacgaagcgggg
ctgccgggcgagctgcgcctgcgtcagaaactggcgctggtggcgatggttggcgctggc
gtgacccgcaatccgctgcactgccaccgtttctggcagcagctgaagggtcagccggta
gagtttacctggcaatcagaagagggcatcagcctggtcgcggtgctgcgcgccgggccg
acggaaagtcttattcaggggctgcatcagtcgttgttccgcgcggaaaaacgcattggc
ctggtgctgtttggcaaaggtaatatcgggtcccgctggctggagctgttcgctcgcgag
cagaccacgctttccgcccgcaccgggtttgaattcatccttgccggggtcgtggatagt
cgccgtagcctgcttaattacgaaggccttgacgccagtcgcgcgctggctttctttaat
gatgaggccgttgagcaggatgaagagtcgctgttcctgtggatgtgcgcgcatccgtac
gatgatttagtggtgctggacgtaaccgccagcgcgcagctggccgaccagtacctcgat
ttcgccagccatggtttccatgttatcagcgcgaataagctggctggcgccagcagcagc
agtaagtatcgccagatccacgacgcgttcgagaagaccgggcgccactggctgtacaac
gccaccgtcggcgccggtttaccggtcaaccatacggtgcgcgatttaattgatagcggc
gataccattctggcgctgagcggtattttctccggcaccctctcatggctgttcctgcag
tttgacggcacagtgccgtttacagacctcgtcgatcaggcctggcagcaggggctgacg
gaaccggacccgcgcgtcgatctctccgggaaagacgtcatgcgcaagctggtgatcctg
gcccgtgaggcgggttacaacatcgagccggatcaggtgcgcgttgagtcgctggtgccc
gcccactgcgaagaggggtctgtcgatcacttctttgagaacggcgaagcgctgaacgag
cagatgctgcagcgtctggaagcggcgcgcgaaatgggcctggtgcttcgctacgtcgcg
cgctttgacgctaacggtaaagcccgcgtcggcgttgaagcggtgcgcgaagagcatccg
ctggcggcgctgctgccgtgtgataacgtctttgctatcgagagccgctggtatcgcgat
aacccgctggtgatccgcggtccgggcgccggtcgtgatgtgaccgccggggcgattcag
tcggatatcaaccgtctggcgcagctgctgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (38)   

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