KEGG   Klebsiella michiganensis HKOPL1: J415_27325
Entry
J415_27325        CDS       T03188                                 
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
koy  Klebsiella michiganensis HKOPL1
Pathway
koy00260  Glycine, serine and threonine metabolism
koy00261  Monobactam biosynthesis
koy00270  Cysteine and methionine metabolism
koy00300  Lysine biosynthesis
koy01100  Metabolic pathways
koy01110  Biosynthesis of secondary metabolites
koy01120  Microbial metabolism in diverse environments
koy01230  Biosynthesis of amino acids
Module
koy_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
koy_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:koy00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    J415_27325 (thrA)
   00270 Cysteine and methionine metabolism
    J415_27325 (thrA)
   00300 Lysine biosynthesis
    J415_27325 (thrA)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    J415_27325 (thrA)
Enzymes [BR:koy01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     J415_27325 (thrA)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     J415_27325 (thrA)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3 ACT_7 ACT DUF6247
Other DBs
NCBI-ProteinID: AHW90822
Position
complement(5761152..5763614)
AA seq 820 aa
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LTNIADAERIFAELLQGLADAQPGFPHAQLKMFVEQEFAQIKHVLHGISLLGQCPDSVNA
SLICRGEKLSIAIMAGLLEARGHNVTVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGGSSD
EDDLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRVMEDEFYLELKEGLLEPLSIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGIGGVGGAL
IEQIKRQQSWLKSKHIDLRVCGVANSRALLTNVHGLNLEHWRDELAEAKEAFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELLRFSGILSGSLSFIFGKLDEGVSFSAATKLA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELSDIIVEPALPAGFDASGDVDSFMA
RLPSLDDEFASRVSKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq 2463 nt   +upstreamnt  +downstreamnt
atgcgtgtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatattctggagagtaatgccaggcaggggcaggtagcgaccgtactgtctgccccg
gcgaagatcactaaccatctggttgcgatgatcgaaaaaaccattggcgggcaggatgcg
ctgaccaatatcgctgatgccgaacgcattttcgccgaacttctgcaaggcctcgccgat
gcccagccgggctttccgcacgctcagttgaaaatgtttgtcgagcaggagtttgcgcaa
atcaaacacgtcctgcacggtattagcctgctcggacagtgcccggatagcgtcaatgcg
tctctgatctgccggggagaaaagctctccatcgctattatggccggcttactggaagcg
cgcggtcataacgtcacggtgattaatccggttgaaaaactgcttgccgttggccattac
ctcgaatccaccgtggatatcgccgagtcgacccgccgcattgccgccagccagatcccg
gctgaccatatggtgctgatggcgggctttaccgccggtaacgaaaagggcgaactggtg
gtgctgggccgtaacggctctgactactccgcagcggtgctggccgcctgcctgcgcgcc
gactgctgtgaaatctggaccgacgttgacggcgtttatacctgcgacccgcgtcaggtg
ccggatgcgcgtttgctgaagtcgatgtcctatcaggaagcgatggagctctcctacttc
ggcgctaaagttttgcacccgcgtactatagcccccatcgcccagttccagatcccctgt
ttaatcaaaaataccggtaatccgcaggcgccgggtacgcttatcggcggcagcagcgat
gaagacgatctgccggtgaaaggtatctctaatctcaacaatatggcgatgttcaacgtc
tccgggccggggatgaaggggatggttggcatggcggcgcgcgtgttcgccactatgtcc
cgcgcgggaatctccgttgttcttatcacccagtcctcttccgaatacagcatcagcttc
tgcgtgccgcagagcgattgcgctcgggcgaagcgggtaatggaagatgaattttatctg
gagctgaaagaggggctgcttgagccgctgtcgatcatggaacgtctggcgattatttcg
gttgtcggcgatggtatgcgcaccctgcgtgggatttccgctaaattcttcgctgcgctg
gcgcgcgccaatatcaacattgtggcgattgcccagggttcttccgagcgctctatctcc
gttgtcgtgagcaacgatgatgctaccaccggcgttcgcgtgacccaccagatgctgttc
aataccgatcaggtgattgaagtgtttgtcattggcatcggcggcgtcggcggcgcgctg
atcgaacagatcaagcgccagcagagctggttgaagagtaaacatatcgacctccgcgtt
tgcggggtggctaactcgcgcgccttgctgaccaacgtacacggcctgaaccttgaacac
tggcgcgatgagctggcggaagccaaagaggcgttcaacctgggacgacttattcgtctg
gtgaaagagtaccatctgctgaacccggtgattgtcgactgtacctccagccaggcggtg
gccgatcagtacgccgatttcctgcgcgaaggtttccacgtggtgacgccgaacaaaaag
gccaatacctcatcgctggattactatcatcagctgcgtcatgccgcgagcagctcacga
cgtaagtttttatacgatactaacgtcggcgcggggctgccggtaatcgaaaacctgcaa
aatttgctgaacgccggtgatgagctgctgcgcttctccggtattctgtccggctcgctg
tcatttatcttcggtaagctggacgaaggcgtaagcttctccgcggcgacgaagctggcg
cgtgaaatgggctataccgaaccggatccgcgcgacgatctttccggcgtggatgtcgcg
cgtaagctgctaatcctcgcgcgtgaaaccgggcgtgaactggagctgtctgacattatc
gtagagccggcgctaccggcgggttttgacgccagcggcgatgtcgacagctttatggca
cgcctgccttctctggatgacgagtttgcctcgcgggtctcaaaagcgcgcgatgaaggt
aaggtcttgcgctatgtcggaaatatcgaagaggatggcacctgccgcgtgaaaatcgcc
gcggttgatggcaacgatccgctgtttaaagtgaaaaacggcgagaatgcgctggcgttc
tacagccactattaccagccgctgccgctggtgctgcgcggttatggtgcgggtaacgat
gtgacggcagctggcgttttcgccgacctgctgcgtaccctgtcatggaagttaggagtt
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (6)   
   Pfam (6)   
All databases (41)   

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