KEGG   Klebsiella pneumoniae subsp. pneumoniae KPNIH10: KPNIH10_04215
Entry
KPNIH10_04215     CDS       T03788                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
kpc  Klebsiella pneumoniae subsp. pneumoniae KPNIH10
Pathway
kpc00010  Glycolysis / Gluconeogenesis
kpc00020  Citrate cycle (TCA cycle)
kpc00620  Pyruvate metabolism
kpc00785  Lipoic acid metabolism
kpc01100  Metabolic pathways
kpc01110  Biosynthesis of secondary metabolites
kpc01120  Microbial metabolism in diverse environments
kpc01200  Carbon metabolism
kpc01210  2-Oxocarboxylic acid metabolism
Module
kpc_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:kpc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    KPNIH10_04215 (aceE)
   00020 Citrate cycle (TCA cycle)
    KPNIH10_04215 (aceE)
   00620 Pyruvate metabolism
    KPNIH10_04215 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    KPNIH10_04215 (aceE)
Enzymes [BR:kpc01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     KPNIH10_04215 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C Viral_DNA_bp
Other DBs
NCBI-ProteinID: AIA35162
Position
889780..892443
AA seq 887 aa
MSERLHNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASAGNY
VNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASYQSSATFYEV
CFNHFFRARTEKDGGDLVYFQGHISPGVYARAFLEGRLTEEQMDNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPLGAIYQAKFLKYLEHRGLKDTSEQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFGGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGQPTVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYVTFPEGSEEHTYLHAQRQKLNGYLPTRQPKFTEKLELPTLA
DFSALLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLVRMYGEAQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFDIDAEKVNPRLA
NT seq 2664 nt   +upstreamnt  +downstreamnt
atgtcagaacgtttacacaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatctgattgaccaactc
ctttctgaagcccgtaaaggcggagtgaaggttgctgcaggcgcttccgccggcaactac
gtcaacactattgccgttgaagatgagccggaatacccgggcaatctggatctggaacgt
cgcattcgttctgcgattcgctggaacgccatcatgaccgttctgcgcgcgtcgaaaaaa
gatctcgaactgggcggccacatggcgtcctatcagtcttccgcgaccttctacgaagtc
tgcttcaaccacttcttccgtgcgcgcactgagaaagatggcggcgatctggtgtacttc
cagggtcacatctctccgggcgtatatgcacgtgcgttcctggaaggccgtctgaccgaa
gagcagatggacaacttccgtcaggaagttcacggcaagggcctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtatccatggggctggggccgttg
ggcgctatctatcaggccaaattcctgaaatatctggaacaccgcggtctgaaagacacc
tccgaacaaaccgtttacgccttcctgggcgacggcgagatggatgagccggaatcaaaa
ggcgctatcaccatcgccacccgtgaaaaactggacaacctggtcttcgtcatcaactgc
aacctgcagcgtctggacggcccggtcaccggtaacggcaaaatcattaacgaactggaa
ggcatcttcggtggtgctggctggaacgttatcaaggttatctggggcggccgttgggat
gagctgctgcgtaaagacaccagcggtaagctgattcagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgttcgtgagcacttcttcggc
aaatatccggaaaccgctgccctggtcgctgactggactgacgagcagatctgggctctg
aaccgcggtggtcacgatccgaagaaagtctacgctgcattgaagaaagcgcaggagacc
aaaggtcagccgaccgtgatcctggcgcataccattaaaggttatggtatgggcgatacc
gctgaaggtaagaacatcgcgcaccaggttaagaaaatgaacatggacggtgttcgctac
gtccgcgatcgtttcaatgtgccggtggcggatgccgatctcgaaaaactgccgtacgta
accttcccggaaggttccgaagagcacacttacctgcacgctcagcgtcagaagctgaac
ggctatctgccgactcgtcagccgaagttcactgagaaactcgagctgccgaccctggcc
gacttcagcgcgctgctggaagagcaaaacaaagaaatctctaccactatcgctttcgtt
cgcgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggtgccgatcatc
gccgacgaagcgcgtaccttcggtatggaaggtctgttccgtcagatcggtatttacagc
ccgaacggccagcagtataccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaagggatcaacgagctgggcgcaggcgcatcctggctg
gctgctgcgacctcttacagcaccaacaacctgccgatgatcccgttctacatctactac
tcgatgttcggcttccagcgtatcggcgatctgtgctgggcggctggcgatcagcaggct
cgcggcttcctgattggcgggacttccggtcgtactaccctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcgtacgcctatgaagtggctgtcatcatgcatgatggtctggtccgtatgtacggc
gaagcgcaagagaacgtttactactacatcactacgctgaacgaaaactaccacatgccg
gccatgccggaaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccatc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtgcgt
gaagcagcgcagatcctggcgaaagactacggcgtgggttccgacgtgtatagcgttacc
tccttcaccgaactggcgcgtgatggccaggattgcgaacgctggaacatgctgcacccg
ctggaaaccccgcgcgtgccgtatatcgctcaggtaatgaacgacgctccggcagtggca
tccactgactatatgaaactgttcgctgagcaggttcgtacttacgtaccggctgatgat
taccgcgtactgggtaccgatggcttcggtcgttccgacagccgtgaaaacctgcgtcac
cacttcgaagtcgatgcttcctatgtggtcgtagcagcgctgggcgaactggctaaacgt
ggtgaaatcgataagaaagtggtggctgacgctatcgcgaaattcgacatcgatgcagaa
aaagttaacccgcgtctggcgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (36)   

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