KEGG   Klebsiella pneumoniae subsp. pneumoniae HS11286: KPHS_p300720
Entry
KPHS_p300720      CDS       T01733                                 
Name
(RefSeq) dihydrofolate reductase
  KO
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
kpm  Klebsiella pneumoniae subsp. pneumoniae HS11286
Pathway
kpm00670  One carbon pool by folate
kpm00790  Folate biosynthesis
kpm01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:kpm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    KPHS_p300720
   00670 One carbon pool by folate
    KPHS_p300720
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:kpm01504]
    KPHS_p300720
Enzymes [BR:kpm01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     KPHS_p300720
Antimicrobial resistance genes [BR:kpm01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    KPHS_p300720
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 11817815
NCBI-ProteinID: YP_005221020
UniProt: A0A0H3GZX6
Position
pKPHS3:complement(41494..41949)
AA seq 151 aa
MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGKVVVMGRKTFESIGKPL
PNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVAGGAEIYTLALPHAHGVFL
SEVHQTFEGDAFFPMLNEQNSSLSQPKPFKL
NT seq 456 nt   +upstreamnt  +downstreamnt
atgaactcggaatcagtacgcatttatctcgttgctgcgatgggagccaatcgggttatt
ggcaatggtcctaatatcccctggaaaattccgggtgagcagaagatttttcgcagactc
actgagggaaaagtcgttgtcatggggcgaaagacctttgagtctatcggcaagcctcta
ccgaaccgtcacacattggtaatctcacgccaagctaactaccgcgccactggctgcgta
gttgtttcaacgctgtcgcacgctatcgctttggcatccgaactcggcaatgaactctac
gtcgcgggcggagctgagatatacactctggcactacctcacgcccacggcgtgtttcta
tctgaggtacatcaaaccttcgagggtgacgccttcttcccaatgctcaacgaacagaat
tcgagcttgtctcaaccgaaaccattcaagctgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (31)   

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