KEGG   Klebsiella pneumoniae 32192: KU54_007260
Entry
KU54_007260       CDS       T03746                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
kpne  Klebsiella pneumoniae 32192
Pathway
kpne03030  DNA replication
kpne03410  Base excision repair
kpne03420  Nucleotide excision repair
kpne03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:kpne00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    KU54_007260 (ligA)
   03410 Base excision repair
    KU54_007260 (ligA)
   03420 Nucleotide excision repair
    KU54_007260 (ligA)
   03430 Mismatch repair
    KU54_007260 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:kpne03032]
    KU54_007260 (ligA)
   03400 DNA repair and recombination proteins [BR:kpne03400]
    KU54_007260 (ligA)
Enzymes [BR:kpne01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     KU54_007260 (ligA)
DNA replication proteins [BR:kpne03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     KU54_007260 (ligA)
DNA repair and recombination proteins [BR:kpne03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     KU54_007260 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     KU54_007260 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     KU54_007260 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      KU54_007260 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT HHH DZR_2 5_3_exonuc Prok-E2_C RNA_ligase DUF2229 DUF1799
Other DBs
NCBI-ProteinID: AJB56588
UniProt: A0A2U0MM43
Position
1433461..1435476
AA seq 671 aa
MEPIEQQLTELRTTLRHHEYLYHVMDAPEVPDAEYDRLMRKLRELESQHPELITPDSPTQ
RVGAAPLTAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTDHLTYCCELKLDGLA
VSILYENGVLVQAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAG
FEKINEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPASHS
ARLLQFKAWGLPVSDRVTLCHTPEEVLTYYRKVEEERPHLGFDIDGVVIKVDSLALQEQL
GFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHN
ADEIERLGLKIGDKVVIRRAGDVIPQVVNVVLSERPADARDVVFPTHCPVCQSDVERVEG
EAVARCTGGLICGAQRKESLKHFVSRRALDVDGMGDKIIDQLVEKEYVHTPADLFRLTAG
KLTGLDRMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAHFGTLEALEQ
ATIEELQKVPDVGIVVATHTFNFFAEESNRDVIAQLLAEGVRWPAPVVVKAEEIDSPFAG
KTVVLTGSLSQLSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVI
DEAEMMRLLGE
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggaaccaatcgaacaacaactgactgaactgcgaaccacgcttcgccatcatgaatat
ctgtaccacgttatggacgcgccggaagtgccggatgcggaatatgaccgcctgatgcgc
aagctgcgcgagctggagagccagcacccggagctgattaccccggattcgccaactcag
agggtgggggcggcgccactcaccgcctttagccagatccgccatgaagtgccgatgctg
tcgctggataacgtgtttgacgaagagagctttctcgccttcaacaagcgggtacaggat
cgcctgaaaagcacagatcatcttacctactgctgcgagcttaagctcgacggcctcgcg
gtgagcattctctacgaaaacggcgtgttggtgcaggcggcaacccgcggcgacggcacc
actggcgaagatattacctctaacgtgcgaactattcgcgccatccccctcaagctgcat
ggcgagaatattcctgcacgccttgaggtacgtggggaagtgttcctcccgcaggccggg
tttgaaaaaatcaatgaggaagctcgccgcaccggcgggaaagtgtttgctaacccgcgt
aatgcggcagcgggttcgctgcgccagctcgatccgcgcatcactgcgaagcgaccgctt
actttcttctgctacggcgtgggcgtgctggagggcggcgagctgccggccagccactcg
gctcggttgctgcagttcaaagcatgggggctgccggtgagcgatcgcgtcaccctgtgc
cacacccccgaggaagtgcttacttactatcgtaaagtcgaggaagagcgtccccacctg
ggctttgacattgatggcgtggtgatcaaagtcgattcgctggcgctgcaggaacagctg
ggtttcgtcgcccgcgcgccgcgctgggccgtggcctttaagttcccggcacaggagcag
atgaccttcgtccgggacgtggagttccaggtgggccgcaccggggcgattacgccggtg
gcgcgtctggagccggtccatgttgccggcgtgttggtgagcaatgccaccctgcataat
gccgatgaaattgaacgcttaggcttgaaaatcggcgacaaggtggtgattcgccgggca
ggcgatgtgatcccgcaggtggttaacgtggtgctttccgagcgtccggcggatgcccgg
gatgtcgtcttcccgacccactgtcctgtatgtcagtcagacgttgaacgggtggaaggc
gaggcggtagcccgctgtacgggcggcctgatctgcggcgcgcagcgcaaagagtcgctc
aagcacttcgtctcccgtcgcgcgctcgacgttgacggcatgggcgacaagatcatcgac
cagctggtggagaaagagtacgtccataccccggcggatctgttccggctgacggcgggg
aaactgaccgggctggatcggatggggccgaagtccgcgcaaaacgtagtcaacgccctc
gagaaagccaaagagacgaccttcgcacgtttcctctacgccttaggtattcgcgaggta
ggagaagcgacggcggcgggcctggcggcgcatttcggcactctcgaagcccttgagcag
gctaccattgaggagctacagaaagtccctgatgtcggcatcgtcgtcgctacccatacc
ttcaacttctttgccgaagagagcaaccgcgatgtcattgcgcaactgctggcggagggg
gttcgctggcctgcgccggtggtggtgaaggcggaagagattgatagcccgtttgcaggc
aaaaccgtggtccttaccggcagcctcagccagctgtcgcgcgatgacgccaaagcgcgt
ctggtggcgctgggggcgaaggtggcaggcagcgtgtcgaagaaaaccgacctggtgatt
gccggcgaagcggcggggtctaagctggcgaaagcgcaggagctgggcatcgaggtgatt
gacgaggccgaaatgatgcgtctgctgggagaataa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (14)   
   Pfam (14)   
All databases (34)   

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