KEGG   Klebsiella pneumoniae subsp. rhinoscleromatis SB3432: KPR_5072Help
Entry
KPR_5072          CDS       T02793                                 

Gene name
arnA
Definition
(GenBank) highly similar to bifunctional polymyxin resistance protein ArnA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TF98)
  KO
K10011  UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305]
Organism
kpr  Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
Pathway
kpr00520  Amino sugar and nucleotide sugar metabolism
kpr01100  Metabolic pathways
kpr01503  Cationic antimicrobial peptide (CAMP) resistance
Module
kpr_M00761  Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
Brite
KEGG Orthology (KO) [BR:kpr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    KPR_5072 (arnA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    KPR_5072 (arnA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01005 Lipopolysaccharide biosynthesis proteins [BR:kpr01005]
    KPR_5072 (arnA)
Enzymes [BR:kpr01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.305  UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
     KPR_5072 (arnA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.13  UDP-4-amino-4-deoxy-L-arabinose formyltransferase
     KPR_5072 (arnA)
Lipopolysaccharide biosynthesis proteins [BR:kpr01005]
 Unusual sugar
  KPR_5072 (arnA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Epimerase Formyl_trans_N GDP_Man_Dehyd Formyl_trans_C 3Beta_HSD NAD_binding_10 NAD_binding_4 RmlD_sub_bind TrkA_N
Motif
Other DBs
NCBI-ProteinID: CCI79300
UniProt: R4YJ45
Position
5196535..5198520
Genome map
AA seq 661 aa AA seqDB search
MKAVVFAYHDMGCTGIQALLDAGYDIAAIFTHPDNPGENHFFGSVARLAAEQGIPVWAPE
DVNHPLWIERIREMKPDVLFSFYYRNLLGDEILNLAPKGAFNLHGSLLPKYRGRAPLNWV
LVNGESETGVTLHRMVNRADAGDIVAQQAVAIGADDAALTLHRKLCAAATELLSRALPAI
LAGTTDERPQDHSQATYVGRRTPEDGRLDWELPAQTLHNLVRAVSDPWPGAFGYAGANKF
IVWKSRVRHDLPAAKPGTVISIAPLIVACQDGALEIVTGQTERVVYMQGAQLAQALGLVS
GAVISSKPVVAIKRRTRVLILGVNGFIGNHLTERLLQDDNYEIYGLDIGSDAINRFLDCP
RFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIAAPIEYTRNPLRVFELDFEENLKIIRDC
VKYNKRIIFPSTSEVYGMCTDKNFDEDSSNLVVGPINKQRWIYSVSKQLLDRVIWAYGDK
NGLKFTLFRPFNWMGPLLDNLNAARIGSSRAITQLILNLVEGSPIKLIEGGKQKRCFTDI
SDGIEALFRIIENKDGRCDGQIINIGNPDNEASIKELAEMLLACFERHPLRDRFPPFAGF
REVESSDYYGKGYQDVEHRKPSIRNAKRCLNWEPKVEMEETVEHTLDFFLRTVELVDDKN
P
NT seq 1986 nt NT seq  +upstreamnt  +downstreamnt
atgaaagccgtagtcttcgcttatcacgatatgggctgcaccggtatccaggctctgctg
gacgccgggtatgatatcgctgctattttcacccacccggataaccctggcgaaaaccat
ttctttggctccgtggcgcgccttgccgccgagcagggtattccggtgtgggcgccggaa
gacgtgaaccatccgctgtggattgagcgtatccgcgagatgaagccggacgtgctgttc
tccttctactatcgcaacctgctgggcgatgagatcctcaatctggcgccgaaaggggcg
ttcaacctgcacggttcgctgctgccaaaatatcgcggccgcgcgccgctgaactgggtg
ttggtcaatggcgaaagcgaaaccggcgtcaccctgcaccggatggtgaaccgcgcagac
gctggcgatatcgtcgcccagcaggccgtggcgattggcgcggatgacgctgccctgacg
ctgcatcgtaagctgtgcgccgccgccactgagctgctgagccgggcgctgccggcgatc
ctcgccggcaccaccgatgagcgtccgcaggatcacagccaggcaacctatgtggggcgt
cgtacgccggaagatggccggctggactgggagctgccggcgcagaccctgcacaatctg
gtgcgtgcggtctcggatccgtggccgggcgccttcggctacgccggagcgaacaagttt
atcgtctggaaatcccgcgttcgccacgatttgccagcagctaaaccgggcaccgtgatc
tccattgcgccgctgatcgtcgcgtgccaggacggggcgctggaaattgtcaccggccag
accgaacgcgtcgtgtacatgcagggcgctcagctggcgcaggcgctgggcctggtgtcc
ggggcggtgatcagcagcaaaccggtggtggcgattaagcgtcgcacccgggtgctgatc
ctcggcgtcaacggctttatcggtaaccacctgaccgagcgtctgctgcaggacgacaac
tatgagatttacggtctggatatcggctccgacgccatcaaccgttttctcgactgtccg
cgtttccactttgtggaaggcgatatcagcattcactccgagtggatcgagtatcacatt
aagaaatgcgacgtggtgttgccgctggtggccatcgccgcgcctatcgaatacacccgc
aacccgctgcgcgtgttcgagctggatttcgaagagaacctgaaaatcatccgcgactgc
gtgaaatacaataagcgcattatcttcccgtcgacctcggaagtgtacggcatgtgcacc
gacaaaaacttcgacgaagatagctccaacctggtggtggggccgatcaacaaacagcgc
tggatctactcggtctccaagcagctgctggatcgcgtgatctgggcctatggcgataag
aacggcctcaagttcacccttttccgtccgttcaactggatggggccgctgctggataac
ctcaacgccgcgcgtatcggcagctcccgcgctatcacccagctgatcctcaacctggtg
gaagggtcgccgatcaagcttatcgaaggcggcaagcagaagcgctgtttcaccgacatc
agcgacggtatcgaagcgctgttccgcatcatcgagaacaaagacggccgctgcgacggg
cagatcattaacatcggcaacccggataacgaagcgagcatcaaagagctggccgaaatg
ctgctcgcctgcttcgaacgtcatccgctgcgcgatcgcttcccgccgttcgccggcttc
cgtgaagtggaaagcagcgattactacggaaagggctaccaggacgttgagcatcgtaag
ccgagcatccgcaacgccaaacgctgcctgaactgggagccgaaggtggagatggaagaa
acggtcgaacacacgctggacttcttcctgcgcacggttgaactggtggacgataaaaat
ccatga

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