KEGG T00910: KP1

Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1): KP1_0248

Entry

KP1_0248          CDS       T00910

Symbol

purH

Name

(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

K00602

phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]

Organism

kpu Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1)

Pathway

kpu00230

Purine metabolism

kpu00670

One carbon pool by folate

kpu01100

Metabolic pathways

kpu01110

Biosynthesis of secondary metabolites

Module

kpu_M00048

De novo purine biosynthesis, PRPP + glutamine => IMP

Brite

KEGG Orthology (KO) [BR:kpu00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    KP1_0248 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    KP1_0248 (purH)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:kpu04147]
    KP1_0248 (purH)
Enzymes [BR:kpu01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     KP1_0248 (purH)
3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     KP1_0248 (purH)
Exosome [BR:kpu04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   KP1_0248 (purH)

SSDB

Motif

Pfam:

AICARFT_IMPCHas MGS

Other DBs

NCBI-ProteinID:

BAH61149

Position

complement(255302..256891)

AA seq 529 aa
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLADKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDGIMQQHGIAPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIINEMDANEGSLTLATRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQLQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSDSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWDTRVAGLDFKRVNGGLLVQDRDLGMVTAGELRVVSKRQPTEQELRDALFC
WKVAKFVKSNAIVYAKDNMTIGIGAGQMSRVYSAKIAGIKAGDEGLEVKGSAMASDAFFP
FRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH

NT seq 1590 nt +upstreamnt +downstreamnt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaggccggtatc
gtcgaattcgcgcaggcgctttccgctcgtggtgtcgagctgctgtccaccggcggcacc
gctcgcctgctggcagataaaggcctgccggttaccgaagtctctgactacaccggtttc
ccggaaatgatggatggacgcgtgaagaccctgcatccgaaagtacacggcggcatcctc
ggtcgtcgcggtcaggatgacggtatcatgcagcaacacggtatcgcgcctatcgatatg
gttgtcgtgaacctttacccgttcgcccagaccgtcgctcgtgaagggtgctcgctggaa
gacgcggtggaaaacatcgatatcggcggcccgactatggtgcgctctgcggcgaagaac
cataaagatgtcgccatcgtagtaaagagcagcgactacgacgccatcattaatgagatg
gacgccaacgaaggttccctcacgctggccacccgcttcgacctcgccattaaagccttc
gaacacaccgccgcttacgacagcatgatcgccaactacttcggcagcatggttccggcc
tatcacggcgaaagcaaagaagccgctggccgcttcccgcgtaccctgaatctgaacttc
attaagaagcaggatatgcgctacggcgaaaacagccaccagcaggcggctttctatata
gaagagaatgtaaaagaggcctccgtggcgaccgccactcagctgcagggcaaagcgctc
tcctataacaacattgccgataccgatgcggcgctggagtgtgtaaaagagttcaacgag
ccggcctgcgttatcgttaagcacgccaacccgtgcggcgttgccgtcagcgactcgatt
cttgacgcctacgatcgcgcttacaaaaccgacccgacctccgcgttcggcggcatcatt
gcctttaaccgcgagctggatgctgaaaccgcgcaggcgatcatctctcgccagttcgtc
gaagtgatcatcgcgccgtccgccagcgaagaagcgctgaaaatcaccgccgcgaagcag
aacgtccgcgtactgacctgcggccagtgggatactcgcgttgccggcctcgatttcaaa
cgcgttaacggtggtctgctggttcaggaccgcgatctcggcatggtcaccgcaggtgaa
ctgcgcgtggtcagcaaacgtcagccaaccgagcaggaactgcgcgatgcgctgttctgc
tggaaagtggcgaaattcgtcaaatccaacgccattgtgtatgccaaagataatatgacc
atcggtataggcgccggtcagatgagccgcgtctactcggcgaaaatcgccggaattaaa
gccggtgatgaaggtctggaagtgaaaggttccgccatggcctctgacgctttcttcccg
ttccgcgacggcatcgatgccgcagccgcggtaggcatcacctgcgttattcagccgggc
ggctctatccgtgacgacgaagtgattgccgccgctgacgaacacggcatcgccatgatc
ttcaccgacatgcgccacttccgccattaa

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