KEGG   Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1): KP1_0257
Entry
KP1_0257          CDS       T00910                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
kpu  Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1)
Pathway
kpu00270  Cysteine and methionine metabolism
kpu00450  Selenocompound metabolism
kpu00670  One carbon pool by folate
kpu01100  Metabolic pathways
kpu01110  Biosynthesis of secondary metabolites
kpu01230  Biosynthesis of amino acids
kpu04980  Cobalamin transport and metabolism
Module
kpu_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:kpu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    KP1_0257 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    KP1_0257 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    KP1_0257 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    KP1_0257 (metH)
Enzymes [BR:kpu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     KP1_0257 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: BAH61157
Position
270443..274216
AA seq 1257 aa
MPVVVFSAPVVYASMVCWLFGLSRALSGASVSSKVEQLHQQLKERILVLDGGMGTMIQGY
RLSEQDFRGERFADWPCDLKGNNDLLVLSKPEVIREIHDAYFEAGADIVETNTFNSTTIA
MADYQMESLSAEINFAAAKLARASADAWTARTPEKPRYVAGVLGPTNRTASISPDVNDPA
FRNITFDQLVAAYRESTRALVEGGVDLILIETVFDTLNAKAAIYAVKEELEALGVDLPLM
ISGTITDASGRTLSGQTTEAFYNSLRHAEALSFGLNCALGPDELRQYVQELSRIAECYVT
AHPNAGLPNAFGEYDLDADTMATQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPP
RQLPEIAVACRLAGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQ
VESGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQG
KGIVNSISMKEGVESFIHHAKLVRRYGAAVVVMAFDEVGQADTRERKIEICRRAYKILTE
EVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFR
GNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPGELRDAVEDVILNRRDDSTER
LLELAEKYRGSKADDGANAQQAEWRTWEVKKRLEYSLVKGITEFIEQDTEEARQQAARPI
EVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGSSNGKMV
IATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVPADKILKTAKEVNADLIGLSGLITPS
LDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVSAL
LSDTQRDEFVARTRKEYETVRIQHGRKKPRTPPVTLAAARENDLAFDWESYTPPVAHRLG
VQTVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGEEAQRLFKDANELLDKLSAE
KTLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPK
LSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMIKAIADRLAEAFAEYLHEKVRKV
YWGYAANENLSNEELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEAHTGMKLTESFA
MWPGASVSGWYFSHPDSKYFAVAQIQRDQVEDYALRKGMTPAEVERWLAPNLGYDAD
NT seq 3774 nt   +upstreamnt  +downstreamnt
ttgcccgttgttgtcttttccgctccggtggtttatgccagtatggtttgttggctattt
ggcctgagtcgagcgttgtcgggagcaagtgtgagcagcaaagttgagcaactgcatcag
cagttaaaagaacgtattctggttctggatgggggcatgggcaccatgatccagggctat
cgtctgagtgagcaggactttcgcggtgagcgctttgctgactggccgtgcgacctgaaa
ggcaacaacgacctgctggtgctcagcaaacccgaagtgatccgcgagatccacgacgcc
tatttcgaggccggcgcggatatcgttgagaccaacacctttaactcgacgaccatcgcg
atggcggattaccagatggaatccctgtcggccgagatcaactttgccgcggcgaagctg
gcccgcgccagcgccgacgcctggacggcccgcacgccggaaaaaccgcgctatgtcgcg
ggcgtgcttggcccgaccaaccgcaccgcttctatttcgcctgatgtgaacgatccggcg
ttccgtaatattacctttgaccagctggtggccgcctatcgcgaatccacccgggcgctg
gtggaaggcggcgtggatctgatcctgattgaaacggtatttgacaccctgaacgctaaa
gcggctatctatgcggtgaaagaggagctggaggcgttaggcgttgacctgccgctgatg
atctccgggaccattaccgatgcctccggccgcacgctttccggacagaccaccgaagcc
ttttataactcgctgcgtcacgccgaagccttatcgtttggtctgaactgcgccctcggg
ccggacgagctgcggcagtacgtccaggagctgtcgcgcattgccgaatgctacgtcacc
gcgcacccgaacgccggcctgcccaacgctttcggcgaatacgatctggacgccgacacc
atggcgacgcaaattcgcgaatgggcggaagccggtttcctcaatatcgttggcggctgc
tgcggtaccaccccggagcatatcgccgccatgagccgggcggtagcgggcctgccgccg
cgtcagttgccggaaattgcggtggcctgccgcctcgccggcctggagccgttgaatatc
ggcgacgatagcctgttcgttaacgtcggtgaacgaactaacgtcaccggctcggcgaaa
tttaagcggctgattaaagaagagaagtacagcgaagcgctggacgttgcgcgtcagcag
gtggaaagcggcgcgcagattatcgatatcaacatggacgaggggatgctcgacgcggaa
gcggcgatggtgcgtttccttaacctgattgccggcgagccggacattgcccgcgtgccg
atcatgattgactcctccaagtgggaagtcattgaaaagggcctgaaatgtattcagggc
aaaggcatcgttaactcgatttcgatgaaagagggcgtcgaatcctttatccaccatgcg
aaactggttcgccgctacggcgccgcggtggtggtgatggctttcgacgaggttggtcag
gccgacacccgcgaacgtaaaattgagatttgccgtcgcgcctacaaaatcctaaccgaa
gaggtcggcttcccgccggaagatattatcttcgaccccaatatctttgccgtcgccacc
ggtatcgaagagcataacaactacgcacaggactttatcggcgcctgcgaagacatcaaa
cgcgagctgccgcatgcgctaatctccggcggggtctccaacgtctccttctccttccgc
ggtaatgacccggtacgtgaggcgatccacgccgtattcctctactacgcgatccgcaac
ggcatggacatggggatcgtcaacgccggtcagctggccatctatgatgacctcccgggc
gagctgcgcgacgcggtcgaagacgtgatcctcaaccgccgcgatgacagtaccgaacgg
ttacttgagctggcggaaaaatatcgcggcagcaaagcggacgacggcgcgaatgcccag
caggcggagtggcgcacctgggaagtgaaaaaacgcctcgaatattcgctggttaagggc
attaccgaatttatcgaacaggacaccgaagaagcgcgtcagcaggccgcccgcccgatt
gaggtcattgaagggccgctgatggacggcatgaacgtggtcggcgatctgttcggcgaa
ggcaaaatgttcctgccgcaggtggtgaaatccgcccgtgtaatgaaacaggcggtggcc
taccttgagccgtttattgaagccagtaaagagcagggctccagtaacggcaaaatggtg
attgccacggtaaaaggcgacgttcatgacattggcaaaaacatcgtcggcgtggtgctg
cagtgcaataactacgaaatcatcgatcttggcgtgatggtcccggcggataaaattctc
aaaacggccaaagaggtaaacgcggatctaattggtctttccgggctgattaccccatcg
ctggacgagatggttaatgtggcgaaagagatggagcgccagggctttaccatcccgctg
ctgataggcggcgcgaccacctcgaaagcgcatacggcggtgaaaatcgagcagaactac
agcggcccgaccgtttacgtacagaacgcctcgcgcaccgtcggcgtggtgtctgcgctg
ctctcggacacgcagcgcgacgagtttgtcgcccgcacgcgcaaagagtatgaaacggtg
cgtatccagcatgggcgtaaaaaaccgcgtacgccgccagtgacccttgccgccgcgcgg
gaaaacgatctggcctttgactgggagagctacacgccgccggtggctcatcgtctggga
gtacagacggtggaagccagtatcgagactctgcgcaactacatcgactggacgccgttc
ttcatgacctggtcgctggcgggtaaatatccgcgcattctggaagatgaagtggtaggg
gaagaggcgcagcgcctgttcaaagatgctaacgagctgctggataagctgagcgcagag
aaaaccctgaacccgcgcggcgtggtgggtctgttcccggccaaccgcgtgggcgacgat
attgaaatctatcgcgatgaaacccgcacccacgtgctgacggtgagccatcatctgcgc
cagcagacggagaaggttggcttcgccaactactgcctcgccgattttgtcgcgccgaag
ctgagcggcaaggcggactacatcggcgccttcgccgtgaccggcggcctggaagaggac
gcgctggcggacgcctatgaagcgcagcatgatgactataacaagatcatgatcaaggcc
atcgccgatcgcctggcggaggcctttgccgagtatctgcatgagaaagtgcgcaaggtt
tactggggatatgcggccaatgagaacctcagcaatgaggagcttattcgcgagaactac
caggggatccgaccggcgccgggatatccggcctgtccggagcacaccgaaaaggggacc
atctggcagctactggacgtcgaagcccataccggcatgaagctcaccgaatcgttcgcc
atgtggccgggcgcatcggtttccggctggtacttcagccatccggatagcaagtacttc
gccgtggcgcagatccagcgcgatcaggtcgaagattacgcgctgcgtaaaggaatgacg
ccggcggaggtcgagcgctggttagcgcctaatctgggctatgatgcggactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (30)   

Download RDF
DBGET integrated database retrieval system