KEGG   Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1): KP1_1622
Entry
KP1_1622          CDS       T00910                                 
Symbol
mrdA
Name
(GenBank) transpeptidase involved in peptidoglycan synthesis
  KO
K05515  penicillin-binding protein 2 [EC:3.4.16.4]
Organism
kpu  Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1)
Pathway
kpu00550  Peptidoglycan biosynthesis
kpu01100  Metabolic pathways
kpu01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:kpu00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    KP1_1622 (mrdA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    KP1_1622 (mrdA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:kpu01011]
    KP1_1622 (mrdA)
Enzymes [BR:kpu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     KP1_1622 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:kpu01011]
 Peptidoglycan biosynthesis and degradation
  DD-Transpeptidase (Class B PBP)
   KP1_1622 (mrdA)
SSDB
Motif
Pfam: Transpeptidase PBP_dimer
Other DBs
NCBI-ProteinID: BAH62369
Position
complement(1563610..1565511)
AA seq 633 aa
MKLQNSFRDYTAESSLFVRRALVAFLGILLLTGVLIANLYNVQIVRFDDYQTRSNENRIK
LVPIPPSRGIIYDRNGTPLALNRTIYQLEMMPEKVDNVQQTLDALRDVVDLTDDDIAGFK
KERARSHRFTSIPVKVNLSEVQVARFAVNQYRFPGVEVKGYKRRYYPYNSALTHVIGYVS
KINDKDVDRLDKEGKLANYASTHDIGKLGIERYYEDVLHGQTGYEEVEVNNRGRVIRQLK
EVPPQAGRDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGAILALVSTPSYDPNLFVDG
ISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTSLFDPGWWQL
PGSEKRYRDWKKWGHGHLNVTKALEESADTYFYQVAYDMGIDRLSEWMSKFGYGHYTGID
LSEERSGNMPTREWKLKRFKKPWYQGDTIPVGIGQGYWTATPIQMNKALMILINDGVVKV
PHLLQSTVEDGKPVPWVQPHEPPVGDIHSGYWEIAKDGMYGVANRGNGTAHKYFASAPYK
IAAKSGTAQVFGLKANETYNAHRISERLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAV
GTIMRQILDHIMLGDNNTTLPSENPAVTAGEDQ
NT seq 1902 nt   +upstreamnt  +downstreamnt
atgaaattacagaattctttccgcgactatacggctgaatcctcgctgttcgtgcgccgg
gcgctggtcgcttttttggggattttgctgcttaccggcgttctgatcgccaacctgtac
aatgtgcaaatcgttcgcttcgacgactatcagacgcgctcgaacgaaaaccgcatcaag
ctggtgccgatcccgccgagccgcggcattatttacgatcgcaacggcaccccgctggcg
cttaaccgcaccatttaccagctggagatgatgccggagaaagtcgataacgtacagcag
acgctggatgcgctacgcgacgtcgtcgatttaaccgacgatgacatcgccggtttcaaa
aaggagcgcgcccgctcccatcgttttacctcgattccggtaaaggtcaacctcagcgaa
gtgcaggtggcccgctttgccgtcaaccagtaccgctttcccggcgtggaagtcaaaggc
tacaagcgtcgttattacccctataattcggcgctgactcacgtcattggctatgtctca
aaaattaacgataaagacgtcgaccgcctggataaagagggcaagctggccaactacgcc
tcgacgcacgacattggtaagctgggtatagagcgttattacgaggacgttctgcacggt
cagaccggctacgaagaggttgaagtgaacaaccgcggccgcgtcattcgtcagctgaaa
gaggtgcctccgcaggccggacgcgacatttacctcaccctcgacctcaagctgcagcag
tatattgaaacgctgctggccggcagccgcgccgccgtggtggtgaccgacccgcgtacc
ggcgctattctggcgctggtttcaaccccgagctatgacccgaacctgttcgtcgacggc
atctccagcaaagattactccgcgctgctcaacgacccgaacacaccgctggtcaaccga
gcgacgcagggggtctatcccccggcgtcgacggtcaaaccctacgtcgccgtctcggcg
ctgagcgccggggtgatcacccgcaacaccagcctcttcgaccccggctggtggcagttg
cccggctcagagaaacgctatcgtgactggaaaaagtggggccacggccatctgaacgtc
accaaagcgctcgaggagtctgcagatacctatttctaccaggtcgcctatgacatgggc
atcgaccgtctctcagagtggatgagcaagtttggctacggccactacaccggtatcgac
ctctccgaggagcgctctggcaacatgccgacccgcgaatggaagctcaagcgctttaag
aaaccctggtaccagggggacaccattccggtgggcatcggccagggttactggaccgcc
acgccgatccagatgaacaaagcgctgatgatcctgattaacgacggcgtggtgaaggtg
cctcatctgctgcagagcaccgtggaagacggcaagcccgtaccctgggtccagccccat
gagccgccggtaggcgatatccattccggctattgggaaatcgccaaagacggcatgtac
ggcgtggccaaccgcggcaacggcaccgcgcacaaatacttcgccagcgcgccgtataaa
atcgcggccaagtcaggtaccgctcaggtgttcggcctgaaggccaacgaaacctataac
gcgcaccggatctccgagcgcttgcgcgaccataaactgatgacagcgtttgcgccttat
aacaacccgcaggttgccgtggcgatgattctggaaaacggcggcgccggcccggcggtc
ggtacgattatgcgccagatcctcgatcacatcatgctgggcgataacaacactacgctg
ccaagcgaaaacccggcggtaaccgcaggggaggatcaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (13)   

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