KEGG   Klebsiella pneumoniae PMK1: PMK1_01724
Entry
PMK1_01724        CDS       T03419                                 
Symbol
metL
Name
(GenBank) Aspartokinase II/homoserine dehydrogenase II
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
kpx  Klebsiella pneumoniae PMK1
Pathway
kpx00260  Glycine, serine and threonine metabolism
kpx00261  Monobactam biosynthesis
kpx00270  Cysteine and methionine metabolism
kpx00300  Lysine biosynthesis
kpx01100  Metabolic pathways
kpx01110  Biosynthesis of secondary metabolites
kpx01120  Microbial metabolism in diverse environments
kpx01230  Biosynthesis of amino acids
Module
kpx_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
kpx_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
kpx_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:kpx00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    PMK1_01724 (metL)
   00270 Cysteine and methionine metabolism
    PMK1_01724 (metL)
   00300 Lysine biosynthesis
    PMK1_01724 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    PMK1_01724 (metL)
Enzymes [BR:kpx01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     PMK1_01724 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     PMK1_01724 (metL)
SSDB
Motif
Pfam: AA_kinase Homoserine_dh NAD_binding_3
Other DBs
NCBI-ProteinID: AIT01213
UniProt: W9BDL3
Position
1844358..1846790
AA seq 810 aa
MSVIAQAGAKGRQLHKFGGSSLADAKCYLRVAGIMKEYSQAGDMMVVSAAGSTTNQLISW
LKLSQSDRLAAHQVQQSLRRYHTELIGGLLEPAAADTLIAAFIHDLERLAGLLDGGVSEA
VYAEVVGHGEVWSARLMAAVLNQLGMEAAWLDARAFLRAERAAQPQVDEGLSYPLLQQLM
AQHPNKRLVVTGFISRNQAGETVLLGRNGSDYSATQIGALAGASRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSASDIDLQLRCSYTPEQGSTRIER
VLASGTGARIVTSHDDVCLVEFQVPAGHDFKLAHKELDALLKRAQLRPLAVGVHADRKLL
QFCYTSEVADSALKLLDEAGLPGELRLRQKLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRAGPTESLIQGLHQSLFRAEKRIGLMLFGKGNIGSRWLELFARE
QTTLSARTGFEFILAGVVDSKRSLLNYDGLDASRALAFFNDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASEQLADQYLDFASHGFHVISANKLAGASSSDKYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLIDSGDTILGLSGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPDQVRVESLVPAHCEEGSVDHFFENGEELNE
QMLQRLEAAREMGLVLRYVARFDANGKARVGVEAVREEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq 2433 nt   +upstreamnt  +downstreamnt
atgagtgtgattgcgcaggcaggggcgaagggtcgtcagctgcacaaatttggtgggagt
agtttagcggatgcgaaatgttacctgcgcgtcgcggggatcatgaaggagtattcgcag
gcgggggatatgatggtcgtctccgccgctggcagcaccaccaaccagctgatcagctgg
cttaagcttagccagagcgatcgccttgctgcgcatcaggttcagcagtcgcttcgccgc
tatcacaccgagctgattggcggtctgctggagcctgcggcggcggatacgttgatagcc
gcctttatccacgaccttgagcgtctggctggtctgctggacggcggggtttccgaagcg
gtctatgcggaagtggtcggccatggggaagtgtggtccgcgcgcctgatggcggcggtt
ctcaaccagctgggtatggaagccgcctggctggacgcgcgcgcgttcctgcgcgcggaa
cgcgccgcgcagccgcaggtggatgagggattatcttacccactgctgcagcagctgatg
gcgcagcatcctaacaaacgtctggtggtgaccggctttatctcccgcaaccaggccggc
gaaaccgtcctgctgggccgtaacgggtctgactactctgccacccagatcggcgcgctg
gcgggcgcctcccgggtcactatctggagcgacgttgccggggtgtacagcgcggatccg
cgcaaggtgaaagacgcctgcctgctgccgctgctgcgtctggacgaagccagcgagctg
gcgcgcctggccgcgccggtgctccatgcccgcacgctacagccggtttccgccagtgat
atcgatctgcagttacgctgcagctacacgccggaacagggttccacgcgcattgagcgc
gtgctggcctccggtaccggcgcacggattgtcaccagccatgacgacgtctgcctggtg
gagttccaggtgccggccggtcacgatttcaaactggcgcataaagagctggacgctctg
ctcaaacgcgcccagctgcgcccgttagccgttggcgtccatgccgaccgtaagctgctg
cagttctgctatacctccgaggtggccgacagcgcgctgaaattgctcgatgaagccggt
ctgccgggcgagctgcgtctgcgtcagaagctggcgctggtggcgatggtgggcgcggga
gtcacccgtaacccgctgcactgccaccgtttctggcagcagctcaaagggcagccggtg
gagttcacctggcagtctgaagaggggatcagcctggtggcggtgctacgcgccgggccg
acggaaagcctgatccaggggctgcatcagtccttgtttcgcgccgaaaagcgtattggc
ctgatgctgttcggcaaagggaacattggttcccgctggctggagcttttcgcccgtgaa
caaactacgctctcggcgcgtaccggtttcgagtttattctcgccggcgtagtcgacagt
aaacgcagcctgctgaattacgacgggctggatgccagccgggcgctggctttcttcaac
gatgaagcggtggagcaggatgaagagtcgctgttcctgtggatgcgcgcgcacccgtat
gatgatttagtggtgctggacgtcaccgccagcgaacagctggccgaccagtatcttgat
ttcgccagccatggcttccacgtcattagcgccaacaagctggcgggcgccagcagcagt
gataaatatcgtcagatccacgacgcgtttgagaagacggggcgccactggctatataac
gccaccgtgggcgccggcttgccggtgaaccatacggtgcgcgacctgatcgacagcggc
gatactattctcggcctgagcggtatcttctcgggaacgctctcctggctgttcctgcag
tttgatggcaccgtgccgttcaccgacctggtggatcaggcgtggcagcaggggctgacc
gagccggatccgcgcgtcgatctgtccggtaaggatgtgatgcgtaagctggtgatcctc
gcgcgggaagcgggctatgacatcgaaccggatcaggtgcgtgtggaatcactggtaccg
gcgcactgtgaagaggggtcggtcgatcacttctttgagaatggcgaagagctgaacgag
cagatgctgcagcgtctggaagcggcccgcgagatggggctggtgctccgctacgtggcg
cgctttgatgccaacggcaaagcacgcgtcggtgtggaagcggtacgcgaagagcacccg
ctggcggcgctgctgccgtgcgataacgtgtttgccatcgaaagccgctggtatcgcgat
aacccgctggtgatccgcgggcccggcgccgggcgcgatgtgaccgccggggcaatccag
tcggatattaaccgcctggcgcagctgctgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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