KEGG   Klebsiella pneumoniae PMK1: PMK1_03655
Entry
PMK1_03655        CDS       T03419                                 
Symbol
topA_2
Name
(GenBank) DNA topoisomerase 1
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
kpx  Klebsiella pneumoniae PMK1
Brite
KEGG Orthology (KO) [BR:kpx00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:kpx03032]
    PMK1_03655 (topA_2)
   03400 DNA repair and recombination proteins [BR:kpx03400]
    PMK1_03655 (topA_2)
Enzymes [BR:kpx01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     PMK1_03655 (topA_2)
DNA replication proteins [BR:kpx03032]
 Prokaryotic type
  DNA Topoisomerases
   PMK1_03655 (topA_2)
DNA repair and recombination proteins [BR:kpx03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      PMK1_03655 (topA_2)
SSDB
Motif
Pfam: Topoisom_bac Topo_Zn_Ribbon TOP1_ZnF Toprim zf-C4_Topoisom Zn_ribbon_recom Toprim_4 DUF1722
Other DBs
NCBI-ProteinID: AIT03097
UniProt: A0A0C7K7N1
Position
3942707..3945304
AA seq 865 aa
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTATKGAKKPK
KDERSALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIA
WHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVS
PLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVTH
KDDKPFRPVSRDETMAAVSMLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFG
VKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYISDKFGKKYLPDSANQYASKEN
SQEAHEAIRPSDVNVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDF
KLKARGRTLRFDGWTKVMPALRKGDEDRTLPLVKQGDRLSLVELTPAQHFTKPPARFSEA
SLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNY
DFTAQMEDRLDQVANHQAEWKEVLNHFFGDFTTQLATAEKDPEEGGMQPNPMVLTSIDCP
TCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKR
RCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHL
KMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVF
LAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYV
ASEKEGKATGWSAFFIDGKWTEAKK
NT seq 2598 nt   +upstreamnt  +downstreamnt
atgggtaaagctctcgttatcgttgagtccccggcaaaagccaaaacgatcaataagtat
ctgggtaatgactacgtggtgaaatccagcgtcggtcatatccgcgatttgccgaccagt
ggatcagcttccaaaaagagcgccgactctaccgccaccaaaggggctaaaaagcctaaa
aaggacgaacgtagtgctctggttaaccgtatgggcgtggatccatggcatgactggaat
gcgcactatgaagtacttccgggtaaagaaaaggtagtttcagaactcaaacagttggcg
gaaaaagctgaccacatctatctcgcaaccgaccttgaccgcgaaggggaagccattgcc
tggcacctgcgggaagtcatcggcggcgatgaacagcgttacagccgcgtggtgttcaat
gagatcaccaaaaacgctattcgtcaggcctttgaaaagccgggcgaactgaatatcgat
cgggttaacgcccagcaggcgcgtcgttttatggaccgcgtggtgggctatatggtttcg
ccgctgctgtggaaaaaaatcgcccgtggtctttctgccgggcgcgtgcagtccgtcgcg
gtccgcctggtggtggagcgtgaacgtgaaattaaagcgttcgtcccggaagagtactgg
gaagtcgacgccagcaccaccacgccgggcggtgacgccctgccgctgcaggtgacccat
aaggacgataagccgttccgtccggtcagccgcgatgagaccatggcggcggtatcaatg
ctggaaaaagccagctacagcgtactggagcgtgaagataagccgaccagcagcaagccg
ggcgcgccgttcatcacctccaccctgcagcaggcggccagcacccgtctgggcttcggc
gtgaaaaagaccatgatgatggctcagcgactctatgaggcagggcacatcacctatatg
cgtaccgactccaccaacctgagtcaggacgcgctgaacatggttcgcggctacatcagc
gacaaatttggcaaaaaatatctgccggatagcgcgaaccagtacgccagcaaagaaaac
tcgcaggaagcgcacgaagcgattcggccgtctgatgtgaacgtgctggcggaaacgctg
aaagatatggaagcggatgcgcagaagctttatcagctgatctggcgccagtttgtcgcc
tgtcagatgacgccggcgcagtacgactccaccacgctgaccgtggctgcgggtgatttc
aaactgaaagcgcgcggtcgcactttacgtttcgacggctggacaaaagtcatgccggcg
ctgcgcaagggcgatgaagaccgaacgctgccgctggtcaaacagggcgaccgcctgagc
ctggtggagctgacgcctgcgcagcactttaccaagccgccggcgcgtttcagcgaggcc
tcgctggtgaaagagctggaaaaacgcgggattggccgtccgtcgacctacgcgtcgatc
atttcgaccattcaggatcgcggctacgtgcgggtggaaaatcgtcgtttttacgccgaa
aaaatgggcgagatcgttaccgaccggctggaagaaaacttccgcgatctgatgaactac
gattttaccgcgcagatggaggatcgcctcgaccaggttgcgaaccaccaggccgagtgg
aaagaggtgctgaaccacttcttcggcgattttaccacccagctggcgacggcagagaaa
gatccggaagagggcggcatgcagccgaacccgatggtgctcaccagcatcgactgcccg
acctgcggccgtaaaatggggatccgtaccgccagcaccggcgttttcctcggctgttcg
ggctatgccttgccgccgaaagagcggtgcaaaaccaccatcaacctggtgccggagaac
gaagtcctcaacgtgctggaaggcgatgacgcggaaaccaacgcgctgcgcgccaaacgt
cgctgccagaagtgtgggacggcgatggacagctaccttatcgatcctaagcgtaagctg
cacgtctgtggtaataacccgacctgcgacggctacgagattgaagagggcgaattccgc
atcaagggctatgacggcccggtggtggagtgcgagaagtgcgggtctgaaatgcacctg
aaaatggggcgtttcggtaagtacatggcctgtaccaacgacgagtgtaagaacacgcgt
aagatcctgcgcaatggcgaagtggctccgccgaaggaagatccggtgccgctgccggag
ctgccgtgtgagaagtctgacgcctactttgtgctgcgcgacggggcggcgggcgtcttc
ctggcggccaacaccttcccgaaatcacgggaaacgcgtgcgccgctggtggaggaactg
taccgcttccgcgatcgtctgccggaaaaactgcgttatctcgccgatgcgccgcagcag
gatccggaaggcaataaaacgctggtacgctttagccgtaaaaccaagcagcagtacgtg
gcgtccgaaaaagagggcaaagcgaccggctggtcagctttctttatcgacggtaagtgg
acggaagccaaaaagtaa

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (8)   
   Pfam (8)   
All databases (18)   

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