KEGG   Loxodonta africana (African savanna elephant): 100662122
Entry
100662122         CDS       T04351                                 
Symbol
MAP3K3
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 3 isoform X1
  KO
K04421  mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04010  MAPK signaling pathway
lav04722  Neurotrophin signaling pathway
lav04912  GnRH signaling pathway
lav05166  Human T-cell leukemia virus 1 infection
lav05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100662122 (MAP3K3)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    100662122 (MAP3K3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100662122 (MAP3K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100662122 (MAP3K3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100662122 (MAP3K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100662122 (MAP3K3)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     100662122 (MAP3K3)
Protein kinases [BR:lav01001]
 Serine/threonine kinases: STE group
  STE11 family
   100662122 (MAP3K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PB1 ABC1 Kinase-like FTA2
Other DBs
NCBI-GeneID: 100662122
NCBI-ProteinID: XP_010592858
Position
Unknown
AA seq 657 aa
MDEQEALDSIMKDLVALQMTRRTRLPGYETMKNKDTGHPNRQKKHNSSSPALLNSPTVTT
GSCAGASEKKKFLSDVRIKFEHNGERRIIPFSRPVRYEDVEHKVATVFGQPLELHYMNNE
LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSRDRNHTSSSPHSGVSRQVRIKASQSAG
DINTIYQPSEPRSRHLSVGSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
VKGGTYPRRYHVSVHHKDYNDGRRTFPRIRRHQGNLFTLVPSIRSLSTNGENLGLAVQYL
DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLGY
NT seq 1974 nt   +upstreamnt  +downstreamnt
atggatgaacaagaagcattggactcgatcatgaaggatctggtggccctccagatgacc
cgacgtacccggctgcctggatatgagaccatgaagaacaaggacacgggtcacccaaat
aggcagaaaaaacacaacagcagcagcccagcccttctgaacagccccacagtaacaaca
ggctcatgtgcaggggccagtgagaaaaagaaatttttgagtgacgtcagaatcaagttt
gagcacaacggggagaggcgaattataccattcagccggcccgtgagatacgaagatgtg
gagcacaaggtggcaacggtatttgggcagcctcttgagctacattacatgaacaatgag
ctctccatcctgctgaaaaaccaagatgatcttgataaggcaattgacattttggataga
agctcaagcatgaaaagccttaggatattgctgctgtcccgggacagaaaccataccagt
tcctctccccactctggggtgtccaggcaggtgcggatcaaggcttctcagtctgcaggg
gatataaatactatctaccagccctctgagcccagaagcaggcacctctctgttggctcc
cagaaccctggccgaagctcgcctccccctggctatgtgcctgagcggcagcagcacatt
gcccggcaggggtcctacaccagcatcaacagtgagggggagttcatcccagagaccagc
gagcagtgcatgctggatcctctgagcagtgctgaaaactccttgtcgggaagctgccaa
tccttggacaggtcagcagacagcccatccttccgtaaatcacgaatgtcccgagcccag
agcttcccagacaacagacaggaatactcggatcgggaaactcagctctacgacaaagga
gtcaaaggtggaacctacccccggcgctaccatgtgtctgtgcaccacaaggactacaac
gatggcagaagaacatttccaagaatacggcgccatcaaggcaacttgttcaccctggtg
ccctccatccgctccctgagcacaaacggcgagaacctggggctggctgtgcagtacttg
gacccccgtgggcgcctgcggagtgcagatagcgagaacgccctctctgtgcaggagagg
aatgtgccaaccaagtctcctagcgcccccattaattggcgccgggggaagctcctgggc
cagggtgccttcggccgggtgtatttgtgctatgatgtcgacacaggacgtgaacttgcc
tccaagcaggtccagtttgacccagacagtcctgagacaagcaaggaggtgagtgccctg
gagtgcgagatccagctgctgaagaacctacagcatgagcgcatcgtgcagtactacggc
tgtctgcgggaccgcgctgagaagacgctgaccatcttcatggagtacatgcctgggggc
tcagtgaaagaccagttgaaggcctatggagctctgacagagagtgtgactcgcaagtac
acccggcagatcctggagggcatgtcctacctgcacagcaacatgattgttcaccgggac
atcaagggagccaacatcctccgagactccgctgggaacgtgaagctgggggactttggg
gccagcaagcgcctgcaaaccatctgcatgtcggggacgggcatgcgctcagtcaccggc
actccatactggatgagccctgaggtgatcagcggtgagggctacggaaggaaggcagac
gtgtggagcctgggctgcactgtggtggaaatgctgacagagaagccaccttgggcagag
tatgaagccatggctgccatcttcaagattgccacccagcctaccaaccctcagctgccc
tcccacatctctgaacacgggcgggacttcctgaggcgcattttcgtggaggcccgccag
agaccttcggctgaggagctgctcacacaccattttgcacagctcgggtactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (6)   
   Pfam (6)   
All databases (55)   

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