KEGG   Loxodonta africana (African savanna elephant): 100664128
Entry
100664128         CDS       T04351                                 
Name
(RefSeq) fibroblast growth factor receptor 2 isoform X1
  KO
K05093  fibroblast growth factor receptor 2 [EC:2.7.10.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav01521  EGFR tyrosine kinase inhibitor resistance
lav04010  MAPK signaling pathway
lav04014  Ras signaling pathway
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04144  Endocytosis
lav04151  PI3K-Akt signaling pathway
lav04550  Signaling pathways regulating pluripotency of stem cells
lav04810  Regulation of actin cytoskeleton
lav05200  Pathways in cancer
lav05215  Prostate cancer
lav05226  Gastric cancer
lav05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100664128
   04014 Ras signaling pathway
    100664128
   04015 Rap1 signaling pathway
    100664128
   04020 Calcium signaling pathway
    100664128
   04151 PI3K-Akt signaling pathway
    100664128
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100664128
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100664128
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100664128
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100664128
   05230 Central carbon metabolism in cancer
    100664128
  09162 Cancer: specific types
   05226 Gastric cancer
    100664128
   05215 Prostate cancer
    100664128
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100664128
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100664128
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:lav04090]
    100664128
   00536 Glycosaminoglycan binding proteins [BR:lav00536]
    100664128
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100664128
Protein kinases [BR:lav01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   100664128
CD molecules [BR:lav04090]
 Proteins
  100664128
Glycosaminoglycan binding proteins [BR:lav00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100664128
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr I-set Ig_3 Pkinase ig Ig_2 V-set Ig_5 ABC1 Ig_4 C2-set_2 V-set_CD47 CBM9_1
Other DBs
NCBI-GeneID: 100664128
NCBI-ProteinID: XP_023396656
Position
Unknown
AA seq 750 aa
MGLTSTWRYGRGLGIGTVTMVSWARFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTK
YQISQPEVYVATPGESLELGCLLKDAAMISWTKDGVHLGPNNRTVLIGEYLQIKGATPRD
SGLYACTAARSVDSETLYFMVNVTDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTEK
MEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESV
VPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVY
SDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPVREKDITASPDYLEIAIYCIGVFLIACMVVTVILCRMK
TTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLA
GVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLFVIVEYASKGNLREYLRARRP
PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK
IADFGLARDINNIDYYKKTTNVSLWWECGEGAGRAFRIKDCRFSELEGTDKAAWLRPLFL
FFCLLFVTFSTSSLSLYFVITCHRVGAYSW
NT seq 2253 nt   +upstreamnt  +downstreamnt
atgggattaacgtccacatggagatatggaagaggactgggcattggcaccgtaaccatg
gtcagctgggctcgcttcatctgcctggtcgtggtcaccatggcaaccttgtccctggcc
cggccctcattcagtttagtcgaggataccacattagagccagaagagccgccaaccaaa
taccaaatctctcaaccagaagtgtacgtggccacgccaggggagtcgctagagttgggc
tgcctgttgaaagatgccgccatgatcagttggactaaggatggggtacatttggggccc
aacaataggacagtgcttattggggagtacttgcagataaaaggcgccacgcctagagac
tccggcctgtatgcttgtactgctgctaggagtgtagacagtgagaccttgtacttcatg
gtcaatgtcacagatgcaatctcatctggggatgatgaggacgacacagatggctccgag
gactttgtcagtgagaacagtaacaacaagagagcaccatactggaccaacacggagaag
atggagaagcggctgcatgctgtccccgcggccaataccgtcaagttccgctgcccagct
ggggggaacccgacacccaccatgaggtggctgaagaacgggaaggaatttaagcaggag
catcgcattggtggctataaggtacgaaaccagcactggagccttattatggagagtgtg
gtcccatccgacaaaggaaattatacctgcgtggtggaaaatgaatacgggtccatcaat
cacacataccacctcgatgttgttgaacggtccccacaccggcccatcctccaagctgga
ctgccggcaaatgcctccaccgtggtcgggggtgacgtggaatttgtctgcaaagtgtac
agtgatgcccagccccacatccagtggatcaagcatgttgaaaagaacggcagcaaatac
gggcccgacgggctgccctaccttaaggttctcaaggctgccggtgttaacaccacggac
aaagagattgaggttctctatattcggaatgtaacttttgaggatgctggggaatatacg
tgcttggcgggtaattctattgggatatcctttcactctgcatggttgacagttctgcca
gctcctgtaagagaaaaggacattaccgcttccccagactacctggagatagccatttac
tgcataggggtcttcttaattgcctgtatggtggtgacagtcatcctgtgccgaatgaag
acaacgaccaagaagccagactttagcagccagccggctgtgcacaagctgaccaagcgc
atccctctgcggagacaggtaacagtttctgccgagtccagctcctccatgaactccaac
accccactggtgaggataacaacacgcctctcctcaacagcagacacgcccatgttggca
ggggtctctgagtacgaattgccagaggatccaaaatgggagtttccaagagataagctg
acgctgggcaaacccctgggggaaggttgctttgggcaagttgtcatggctgaagcagtg
ggaatcgacaaagagaagcccaaggaagcagtcactgtggctgtgaagatgttgaaagat
gatgccacagagaaagacctttccgatctggtgtcagagatggagatgatgaagatgatt
ggaaaacacaaaaacatcatcaatctcctgggagcctgtacgcaggatggcccactcttt
gtcatagtggagtacgcctcgaagggtaacctccgcgagtacctgcgtgcccgcaggccc
cctgggatggagtactcctacgacatcaaccgcgttcctgaggaacagatgaccttcaag
gacttggtgtcgtgcacataccagctggccagaggcatggagtacttggcttcccaaaaa
tgtattcatcgagacttagcagccagaaatgttttggtaacagaaaacaatgtgatgaaa
atagcagacttcggactggccagagacatcaacaatatagactactacaaaaagaccacg
aatgtaagtctatggtgggagtgtggtgagggggcgggcagagcgttccggataaaagat
tgtagattttcagagctggaaggtactgacaaggctgcatggctccgccctttattttta
ttcttttgcttactctttgtcaccttctcaacaagcagtcttagcctgtattttgtcatt
acttgccatcgagttggcgcctactcgtggtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (13)   
   KEGG PATHWAY (13)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (13)   
   Pfam (13)   
All databases (55)   

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