KEGG   Latimeria chalumnae (coelacanth): 102357545
Entry
102357545         CDS       T02913                                 
Symbol
RAF1
Name
(RefSeq) Raf-1 proto-oncogene, serine/threonine kinase
  KO
K04366  RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
lcm  Latimeria chalumnae (coelacanth)
Pathway
lcm04010  MAPK signaling pathway
lcm04012  ErbB signaling pathway
lcm04068  FoxO signaling pathway
lcm04140  Autophagy - animal
lcm04150  mTOR signaling pathway
lcm04210  Apoptosis
lcm04218  Cellular senescence
lcm04270  Vascular smooth muscle contraction
lcm04370  VEGF signaling pathway
lcm04371  Apelin signaling pathway
lcm04510  Focal adhesion
lcm04540  Gap junction
lcm04625  C-type lectin receptor signaling pathway
lcm04810  Regulation of actin cytoskeleton
lcm04910  Insulin signaling pathway
lcm04912  GnRH signaling pathway
lcm04914  Progesterone-mediated oocyte maturation
lcm04916  Melanogenesis
lcm05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:lcm00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102357545 (RAF1)
   04012 ErbB signaling pathway
    102357545 (RAF1)
   04370 VEGF signaling pathway
    102357545 (RAF1)
   04371 Apelin signaling pathway
    102357545 (RAF1)
   04068 FoxO signaling pathway
    102357545 (RAF1)
   04150 mTOR signaling pathway
    102357545 (RAF1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102357545 (RAF1)
  09143 Cell growth and death
   04210 Apoptosis
    102357545 (RAF1)
   04218 Cellular senescence
    102357545 (RAF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102357545 (RAF1)
   04540 Gap junction
    102357545 (RAF1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102357545 (RAF1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102357545 (RAF1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102357545 (RAF1)
   04912 GnRH signaling pathway
    102357545 (RAF1)
   04914 Progesterone-mediated oocyte maturation
    102357545 (RAF1)
   04916 Melanogenesis
    102357545 (RAF1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    102357545 (RAF1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102357545 (RAF1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lcm01001]
    102357545 (RAF1)
Enzymes [BR:lcm01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102357545 (RAF1)
Protein kinases [BR:lcm01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   102357545 (RAF1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase RBD C1_1 Kinase-like ABC1 zf-RING-like Pkinase_fungal C1_2 zf-C3HC4_2
Other DBs
NCBI-GeneID: 102357545
NCBI-ProteinID: XP_006004462
Ensembl: ENSLACG00000007082
Position
Un
AA seq 673 aa
MISKHCQSWSMDHLQRAWNGFGVKDSVFDGSTCMSPTIVEPFAYARRASDDGKLMDHSRA
STTIRVYLPHKQRTVANVRNGMTLQDCLIKALKVRGLQPECCAVFRLVHGQRGRRFRVDW
NTDATSLIGEELQVDFLDHVPLTTHNFVRKTFLKLAFCDICQKFLLNGFRCQTCGYKFHE
HCSTKVPTMCVDWSNIRQMLLFPNSNIGDSGVPSLPSLTTRRMRESLSRFSVSYEHRHST
PHAFNFNPATPAPEGSLSRRQRSTSTPNVHMVSTTMPVDSRVIENGSLNSSPRSWCRRFC
LRGRDAIRSHNESVSPSALSGSPPSLSPTGWSQQKTPVPAHREKAPGSSTQEKNKIRSRV
QRDSSYYWEIEASEVMLLTRIGSGSFGTVYKGKWHGDVAVKILKVTDPTPEQFHAFRNEV
AVLRKTRHVNILLFMGYMTKGNLAIVTQWCEGSSLYKHLHVQETKFQMIQLIDIARQAAQ
GMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPSGSILWMAP
EVIRMQDNNPYSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMIGRGYLSPDLSKLY
KNCPKAMKRLVADCVKKTREDRPLFPQVLSSVELLQHSLPKINRSASEPSLHRVTQTEDI
NSFTLTSTRLPVF
NT seq 2022 nt   +upstreamnt  +downstreamnt
atgatttctaaacattgtcagtcttggtcaatggatcaccttcagagagcctggaatggt
tttggagttaaggattcggtatttgatggatctacatgtatgtctcccaccattgttgag
ccatttgcttatgcgcgtcgagcgtcagatgatggcaaacttatggatcactccagagct
agcactacgatccgggtctacctacctcacaagcagcgcactgtggctaatgtgcggaat
ggtatgaccctacaggattgcctcatcaaagctcttaaagtccgaggcctacagccagaa
tgttgtgcagtcttcaggctcgttcatggacagagaggcaggcgcttccgtgtagattgg
aacacagatgctacctcgttgattggtgaggagctgcaggtagattttctggatcacgtt
cccctgacaacacacaattttgtacggaagacctttctaaaattggcattctgtgatatt
tgccagaagttcctgctaaatggctttcgttgtcagacatgtggttacaagttccatgag
cattgcagtaccaaggtcccaaccatgtgtgttgactggagtaacattcgtcagatgtta
ttgtttccaaattctaacattggtgatagtggggttccttcactaccttccctgaccaca
cgacgtatgcgggaatctctctctcgcttttcagtcagttatgaacacagacattctaca
cctcacgcatttaacttcaacccagcgaccccagcccctgaaggctcactgtcccggagg
caaagatccacatccactcccaacgtccatatggtcagcacaactatgccagtcgacagc
cgggtcattgagaatggcagcctgaactcttctcccaggtcctggtgcagacggttttgt
ttaaggggcagagatgctatcagaagtcacaatgaatcagtatccccctccgcactttct
ggcagtcctcctagtttaagtccaacaggttggtctcagcaaaaaaccccagtcccggct
cacagagagaaagcaccaggatcatccacacaggagaaaaataaaatcagatctcgtgtc
caaagggattcaagttattattgggaaatagaagccagtgaggtcatgctcttgacaaga
atagggtctggctcctttgggacggtatataaagggaaatggcatggagatgtagctgtt
aagattctaaaagtgactgatccaacacctgaacaattccatgccttcagaaatgaagta
gcagtattgagaaaaacacggcatgtgaacatcttgctatttatgggctacatgaccaag
gggaacttggccatagtgacgcagtggtgtgaagggagcagtctgtacaaacacttgcat
gttcaggagaccaagttccagatgatccagctgatagacattgccaggcaggctgcccag
ggaatggactatctacatgcaaagaacatcatccacagagacatgaagtcaaacaatata
tttctacatgaaggcttgacagtgaagataggagattttgggttggcaacagtaaaatcc
aggtggagtggctctcaacaggtggaacagccttcaggatcaattctgtggatggcacct
gaagtaatccggatgcaggataataatccctatagctttcagtcagatgtctactcttat
gggatagtactatatgagctaatgacaggagagctcccctactcccatatcaataataga
gatcagatcatttttatgattggacgaggttatctgtctcctgatctcagcaaactttat
aagaattgtcccaaagctatgaaaagacttgttgcagactgtgtgaagaaaaccagggaa
gacagacccctctttccacaggttttatcatcagttgagcttcttcagcattcattaccc
aaaatcaaccgcagtgcatcagaaccttccctccatcgtgtaacacagactgaggacata
aactcttttactttaacttccacaagactgccggttttttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (10)   
   RefSeq(nuc) (8)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (67)   

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