KEGG   Leishmania major: LMJF_29_1830
Entry
LMJF_29_1830      CDS       T01014                                 
Symbol
GCVL-1
Name
(RefSeq) putative dihydrolipoamide dehydrogenase
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
lma  Leishmania major
Pathway
lma00010  Glycolysis / Gluconeogenesis
lma00020  Citrate cycle (TCA cycle)
lma00260  Glycine, serine and threonine metabolism
lma00280  Valine, leucine and isoleucine degradation
lma00310  Lysine degradation
lma00380  Tryptophan metabolism
lma00620  Pyruvate metabolism
lma00630  Glyoxylate and dicarboxylate metabolism
lma00640  Propanoate metabolism
lma00785  Lipoic acid metabolism
lma01100  Metabolic pathways
lma01110  Biosynthesis of secondary metabolites
lma01200  Carbon metabolism
lma01210  2-Oxocarboxylic acid metabolism
lma01240  Biosynthesis of cofactors
Module
lma_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
lma_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:lma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    LMJF_29_1830 (GCVL-1)
   00020 Citrate cycle (TCA cycle)
    LMJF_29_1830 (GCVL-1)
   00620 Pyruvate metabolism
    LMJF_29_1830 (GCVL-1)
   00630 Glyoxylate and dicarboxylate metabolism
    LMJF_29_1830 (GCVL-1)
   00640 Propanoate metabolism
    LMJF_29_1830 (GCVL-1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    LMJF_29_1830 (GCVL-1)
   00280 Valine, leucine and isoleucine degradation
    LMJF_29_1830 (GCVL-1)
   00310 Lysine degradation
    LMJF_29_1830 (GCVL-1)
   00380 Tryptophan metabolism
    LMJF_29_1830 (GCVL-1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    LMJF_29_1830 (GCVL-1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lma04147]
    LMJF_29_1830 (GCVL-1)
Enzymes [BR:lma01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     LMJF_29_1830 (GCVL-1)
Exosome [BR:lma04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   LMJF_29_1830 (GCVL-1)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox FAD_oxidored DAO Pyr_redox_3 FAD_binding_3 HI0933_like Lys_Orn_oxgnase Thi4 AlaDh_PNT_C GIDA NAD_binding_8 ThiF FAD_binding_2 Lycopene_cycl 3HCDH_N 2-Hacid_dh_C
Other DBs
NCBI-GeneID: 12981045
NCBI-ProteinID: XP_003722265
UniProt: E9AE44
Position
29:complement(817063..818589)
AA seq 508 aa
MKRTIVAWTRKFDVCVLGGGPAGIAAAVRAYELGKKACIIEESRIGGADFWNGALQSKTL
WEMAKFARYTMGNTSHRFMKSVIELPKIKHSNLIKAITNAAETRETQTLEVLANAHIEVL
SGLGSFKTPNSVAVTKKDGTEETVEADYFVIATGAHPRPHPTAVADGKVVFTSDDIMMQP
LPKSIVIIGAGVIGCEFASIFANFGVTQVNIIEKSGRILPMEDEDIALFVQTLLEQKGVC
FHHHSAMESSSINDGKFHYTLRDVRDNSLHQHVTDSALVSIGRVPAISKLNLEAIGITVK
GNRIDRDEFLRIEPHKHIYACGDTCTRVALVNVAELEGRACIDHMYTPYPEEQLKLKLDN
LSTIMFLDQEVAAVGLNEQQCQKMSISYKMARYSYEYVGRALAMGNTRGFIKLVVTNDKK
MQVLGVRAVGPHASSIIELASLAIHNRDSAYDLRNLHAVYPAITQGFQECLHMLLGSSIL
KPDVFPKLVVREWNPPHFQHGRAYAHTK
NT seq 1527 nt   +upstreamnt  +downstreamnt
atgaagcgcactatcgttgcatggacgaggaaattcgatgtgtgcgtgctaggcggtggt
ccagccggcatcgccgcggccgtccgcgcgtacgaactggggaaaaaggcctgcatcatt
gaagagtcccgtattggtggtgctgatttttggaatggtgcgctgcagtccaagacattg
tgggaaatggcgaaattcgcgcgatacacaatgggcaacacgtctcaccgtttcatgaag
tccgtaatcgagcttccgaagataaaacacagcaacctaatcaaggccatcacaaacgcc
gccgaaacgcgtgaaactcagacgctggaagtcctcgctaacgcccacatcgaggtgctt
tccggattaggttcctttaagacaccgaactcggtagctgtcacgaagaaagacggcacg
gaggaaactgtcgaggctgattactttgtgattgctacaggtgcccacccacggcctcac
ccaactgccgtcgccgacggaaaggttgtctttacctccgatgatataatgatgcaaccg
cttcccaagagtattgttattatcggcgcgggtgtcatcggatgtgagtttgcatccatt
ttcgccaatttcggagtaacccaagtgaatattattgaaaaaagtggccgtattttgcct
atggaggatgaagatatcgcactcttcgtacaaacacttcttgagcaaaaaggcgtttgt
tttcatcatcactccgcgatggagagcagtagcatcaatgatggaaagttccactacact
ctcagagatgttcgtgacaactctcttcaccaacatgtcacggacagcgctctcgtctcc
atcggacgcgtaccagcaatttcaaagctgaacttggaggcaattggcatcacggtgaaa
ggtaaccgcatcgaccgagacgaattccttcgcatcgaaccacacaagcacatctatgcc
tgtggagatacgtgcacgcgtgtcgctctcgtcaacgttgccgaactggaggggcgcgcg
tgcattgaccatatgtacacaccatatcctgaggagcaattgaagctcaagctggacaat
ctctccaccatcatgttccttgatcaagaagtggcagctgtcggcctaaacgagcagcag
tgccaaaagatgtccatcagctacaagatggcacgatacagctacgaatacgtagggcgt
gcattagctatgggcaacacgagaggttttatcaaactagttgtgacaaacgacaaaaag
atgcaagttcttggcgtgcgcgcagtgggtccccatgccagcagtattattgagctcgcg
tcactggccatccacaaccgcgactctgcatacgacttgcgcaatcttcacgccgtctac
cccgctatcactcagggattccaagagtgccttcatatgcttttgggctcctcgattttg
aaaccggacgtcttcccgaagcttgttgtgcgagaatggaatccacctcatttccagcac
gggcgcgcatacgcgcatacaaaatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (22)   
   KEGG PATHWAY (15)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (18)   
   Pfam (18)   
All databases (89)   

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