KEGG   Listeria monocytogenes 08-5578 (serotype 1/2a): LM5578_2189
Entry
LM5578_2189       CDS       T01157                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
lmn  Listeria monocytogenes 08-5578 (serotype 1/2a)
Pathway
lmn00290  Valine, leucine and isoleucine biosynthesis
lmn00620  Pyruvate metabolism
lmn01100  Metabolic pathways
lmn01110  Biosynthesis of secondary metabolites
lmn01210  2-Oxocarboxylic acid metabolism
lmn01230  Biosynthesis of amino acids
Module
lmn_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:lmn00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    LM5578_2189 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    LM5578_2189 (leuA)
Enzymes [BR:lmn01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     LM5578_2189 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Herpes_gp350_A
Other DBs
NCBI-ProteinID: ADB68936
Position
2178130..2179668
AA seq 512 aa
MKKIQFFDTTLRDGEQTPGVNFDVKEKIQIALQLEKLGIDVIEAGFPISSPGDFECVKAI
AKAIKHCSVTGLARCVEGDIDRAEEALKDAVSPQIHIFLATSDVHMEYKLKMSRAEVLAS
IKHHISYARQKFEVVQFSPEDATRSDRAFLIEAVQTAIDAGATVINIPDTVGYTNPTEFG
QLFQDLRREIKQFDDITFASHCHDDLGMATANALAAIENGARRVEGTINGIGERAGNTAL
EEVAVALHIRKDFYQAETNIVLNQFKNSSDLISRLSGMPVPRNKAVIGGNAYAHESGIHQ
DGVLKNPDTYEIITPALVGVDKNSLPLGKLSGKHAFNTRMEEMGYTLTEQEQKDAFKRFK
QLADAKKEVTEEDLHALILGQSSESADDFELKHLQVQYVTGGVQGAIVRIEERDGALVED
AATGSGSIEAIYNTINRLMKQDIELTDYRIQAITAGQDAQAEVHVVIKNDKGAEFHGIGI
DFDVLTASAKAYLQASGKSKTASKQADFEEVK
NT seq 1539 nt   +upstreamnt  +downstreamnt
atgaagaaaatccagttttttgatactacacttagagatggcgaacaaacccctggagtt
aattttgacgtaaaggagaaaatccagattgccttacaactcgaaaaacttggaattgat
gtgattgaagccggctttccgatttcttctcctggagattttgaatgcgtcaaggccatt
gcaaaagcgattaaacattgttctgtaacagggctagcgcgctgtgttgaaggagatatc
gaccgcgcggaagaagcgcttaaagacgctgtttctccgcaaatacatatcttcttagca
acgagcgatgtgcatatggaatacaaattaaaaatgagtcgggcggaagttcttgcttcc
attaaacaccacattagttatgcaagacaaaaattcgaagtagtacagttttcaccagaa
gatgcaactcggtcagatcgtgcttttctaattgaggccgttcaaacagcaattgatgcc
ggggcaactgtcatcaacattccggacacggtcggatatactaacccaaccgaattcgga
cagctattccaagatttgcgtagggaaattaaacaatttgatgatattactttcgcttcc
cattgtcatgatgaccttggtatggcgactgcaaatgcacttgctgcaatcgaaaatggc
gcaagacgcgtcgaaggtacaattaatgggattggcgaacgagctgggaatacggctctt
gaagaagttgctgtcgcgctgcatattcgcaaagatttttatcaagcagaaacaaatatc
gttttgaaccaatttaaaaattctagtgatctgattagtcgtttgtcgggtatgcctgtt
ccgcgtaataaagccgtaattggtggtaatgcttacgcgcacgagtccggtattcatcaa
gatggcgtgctgaaaaacccagatacgtatgaaatcatcacccctgcccttgtcggcgtg
gataaaaactcgcttcctcttggtaaactttctggcaaacatgccttcaatacgcgcatg
gaagaaatgggctacacactaaccgaacaagaacaaaaagatgcctttaaacgtttcaaa
caactagcagatgcgaaaaaagaagtaactgaagaagacttgcacgcgttaattctcggc
caatcttccgagtcagccgatgatttcgaactaaaacatttgcaagttcaatatgttact
ggcggcgtccaaggtgcgattgttcgcattgaagaacgtgatggcgctctagtagaagat
gcagcaactggttcaggtagcattgaagcgatttacaacacaattaatcgcctaatgaaa
caagacatcgaattaaccgattatcgtatccaagcaattacagccggccaagatgcccaa
gcagaagtccatgtcgtcattaaaaatgacaaaggcgctgagttccatggtatcggtatt
gattttgacgttttaaccgctagtgctaaagcttatttgcaagcatcaggcaaaagcaaa
accgccagtaagcaagctgatttcgaggaggtaaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (23)   

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