KEGG   Legionella pneumophila 2300/99 Alcoy (serogroup 1): lpa_02278
Entry
lpa_02278         CDS       T01232                                 
Symbol
thiD
Name
(GenBank) thiamine-phosphate pyrophosphorylase
  KO
K14153  hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
Organism
lpa  Legionella pneumophila 2300/99 Alcoy (serogroup 1)
Pathway
lpa00730  Thiamine metabolism
lpa01100  Metabolic pathways
lpa01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:lpa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    lpa_02278 (thiD)
Enzymes [BR:lpa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     lpa_02278 (thiD)
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     lpa_02278 (thiD)
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     lpa_02278 (thiD)
SSDB
Motif
Pfam: Phos_pyr_kin TMP-TENI PfkB Carb_kinase HK
Other DBs
NCBI-ProteinID: ADG24900
Position
1796542..1798008
AA seq 488 aa
MKKPIVWTIAGVDSSGLAGVHADMETFSRLNVRACSVITAVTAQNAHSIIAVEAISRDQV
AAQCRALELNLKPDAIKIGMLCSTPICEEIAYFLKGYEGFVVLDPIITSSSGTNLFFPDL
QQHKENLIQLFPYVTIITPNRIEAEIILNRSISSYQDIINAASDLLSLGAKQVLLKGGHV
KDNSFSQDYWTDGKESFWIANRRFPETNYRGTGCVLSSALTACLALGYSIKDAIVIAKMY
VNRGIRQSIELDKDASQLYHDGWPEDEADLPYLSPTPFIKPVPSFKKCSMGFYPIVDSSH
WLEMLLPLGIKCIQLRIKEASKERLEEEIKRSVHLANQYNAALFINDYWELAIHYGAAGV
HLGQEDLEKADVDRINRSGLFLGISTHCYYEVARAHALNPSYVACGPIYETTSKIMPFQA
QGIARLERWRKTLHYPLVAIGGITLKNLSDVLKTKIDGVSVISAITKASAPLVAAKQFLT
QMNESHNE
NT seq 1467 nt   +upstreamnt  +downstreamnt
atgaaaaaaccgattgtttggacaattgctggtgttgactcatctggattagctggtgtc
catgctgacatggaaacttttagtcgcttgaatgtcagggcttgttcagtcatcaccgca
gtaactgcacaaaatgctcactcaattatagcagtagaagcgatatccagagatcaggtt
gctgctcagtgccgtgccttggaattaaatttaaaaccggatgccattaaaattggtatg
ttatgctctacaccaatctgtgaagaaatagcttattttttaaaaggttatgaaggattt
gttgttcttgatccgataattacctcctcctcgggaactaacctgttttttccagattta
caacagcataaagaaaatctaattcaattgtttccgtacgttactattattactcctaat
cggattgaagcagaaattattttgaatcggagcatttcttcttatcaggatataatcaat
gctgcttcagatcttttatcactgggagcaaagcaggtgttactgaaaggaggacatgta
aaagataactcattcagccaagattactggactgatggaaaagagtcattttggattgca
aatcgtcgttttcctgaaacaaattaccgtgggacaggctgtgttctatcttcagcactc
acagcttgtcttgcgctaggctattcaataaaagatgctattgttattgctaaaatgtat
gtcaatcgcggcatacgccaatcaatagaacttgataaagacgcctcgcaactttatcac
gatggttggccagaagatgaggccgatctcccctatttatcaccaacaccattcattaaa
ccagttccctcatttaaaaaatgttctatgggtttttatcccattgttgatagtagccac
tggttagaaatgcttttgccattgggaattaagtgcattcagttacgaataaaggaagcc
tctaaagagcggttggaagaagagataaaacggagtgtccatttggcaaatcagtataat
gctgcattatttattaatgattactgggaacttgctattcattatggtgctgcaggagtt
caccttggccaagaggatctggaaaaagctgatgtcgatagaattaatcgatcaggttta
ttcttaggcataagtacgcattgctattacgaagttgctcgggctcatgctcttaaccct
tcctacgttgcttgcggccccatatatgaaacaaccagcaaaataatgccatttcaagca
caaggaattgcacgacttgaacgttggcgaaaaacgcttcattatccattggtcgccatt
ggaggtataactttaaagaacctttctgatgtcttaaaaacaaaaattgatggtgtgtca
gtgatctctgctattacaaaagcatcagcacctttagttgcagccaaacaatttttaact
caaatgaatgaatcacataatgaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (3)   
   KEGG MODULE (3)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (34)   

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