KEGG   Lacticaseibacillus rhamnosus LOCK908: LOCK908_2618
Entry
LOCK908_2618      CDS       T02731                                 
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
lrc  Lacticaseibacillus rhamnosus LOCK908
Pathway
lrc00300  Lysine biosynthesis
lrc00550  Peptidoglycan biosynthesis
lrc01100  Metabolic pathways
lrc01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:lrc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    LOCK908_2618
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    LOCK908_2618
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    LOCK908_2618
Enzymes [BR:lrc01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     LOCK908_2618
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase LpxD
Other DBs
NCBI-ProteinID: AGP75225
Position
complement(2603693..2605084)
AA seq 463 aa
MMKMTLAEIARVVKAQPLSETVGSQVATGVAFDSRRLKPGMLFVPLHGERDGHEFIPAAA
AAGAVATFVAEDHLPMTTKLPTLVVPDPLAAMQKLAQYYLLMKVNPKVVAITGSNGKTTT
KDMTAAILATQYHVVKTPDNYNNEIGVPMTILSMEPNTEVLVLEMGMDRPGQLHALSSLA
EPDVAVITMIGEAHIEFFKTRAKIADAKMEITDGLKEDGTFIFNGDEPLLVSRAKQVTQS
QETFGLHPENTLFAHSISGHRNHTEFTVEQWPELTFSIPIMGEYNVVNALAALLVGRRFH
VKPEAMQKALAHFQVTANRTQWLIGDVGEQILSDVYNANPTAMKAVIHDFSEFQTAGRHI
AVLGDMLELGDQSRALHAGLADALDPHEIQEVYLYGSEMQALAEALTTKYPQDQVHYYPL
DAKSTMIRDLQNDVGHDDMVLLKASHGLHLETVLAALVAGGHA
NT seq 1392 nt   +upstreamnt  +downstreamnt
atgatgaaaatgacattggcagagatcgcacgtgtcgtaaaagcccagccactctctgaa
acagtcggttcgcaagtggcaaccggggtggcatttgattcgcggcgattgaagccggga
atgttatttgtcccattgcatggcgagcgtgacgggcacgagtttattccagcggcggct
gctgcgggggcagtcgcaacttttgtggcagaggaccatctgccaatgacgactaaactg
ccaacattggtggtcccggatccgctggcagccatgcagaagttagcccagtattatttg
ctaatgaaagtgaaccctaaagtcgttgccatcaccggcagcaatgggaagaccacgaca
aaagacatgactgcggcgattttggcaacgcaataccatgttgtgaagacgccggataat
tacaataatgaaatcggtgtcccaatgacgattctcagtatggagcccaataccgaagtg
ctggtgcttgagatggggatggatcggcccggccaattacatgcattgtcatcgttggcc
gaaccggatgtggcagtgattaccatgattggcgaggcccatattgaatttttcaagacg
cgcgctaagattgcagatgccaagatggaaattacggatggcttgaaagaggatggcacc
tttatttttaacggtgacgaaccgttattggtgagccgcgctaagcaagtcacccaatca
caagaaacatttggtttacatccggaaaatacgctttttgcccattcgattagcggccat
cgcaatcataccgaatttaccgtcgaacagtggccggaattgaccttttcaattcctatt
atgggtgaatacaatgtggtcaatgctttggctgcgttgctagtaggtcggcgtttccat
gtcaaaccggaagccatgcaaaaagcactggcgcattttcaggtgacggctaatcgcaca
caatggttaattggcgatgtcggcgagcagattctgagcgatgtttacaatgccaaccca
accgcgatgaaagcagtcatccatgattttagcgaatttcagacggcaggacgccacatt
gctgttttaggtgacatgcttgaacttggcgatcaaagccgggcgttgcatgcgggacta
gccgatgcacttgatccgcacgaaattcaggaggtttacttatacggttcggaaatgcag
gcacttgccgaagcgttaacgacaaagtatccgcaagatcaagtacactattacccgctg
gatgccaaaagtaccatgattcgcgatttgcaaaacgatgtcgggcacgatgacatggtg
ttgctaaaagcgagccatggtctgcatctggaaactgttttggctgcgctggtcgcaggc
ggacatgcgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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