KEGG   Limosilactobacillus reuteri subsp. reuteri DSM 20016: Lreu_0477
Entry
Lreu_0477         CDS       T00535                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
lre  Limosilactobacillus reuteri subsp. reuteri DSM 20016
Pathway
lre00470  D-Amino acid metabolism
lre00550  Peptidoglycan biosynthesis
lre01100  Metabolic pathways
lre01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:lre00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Lreu_0477
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Lreu_0477
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Lreu_0477
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:lre01011]
    Lreu_0477
Enzymes [BR:lre01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Lreu_0477
Peptidoglycan biosynthesis and degradation proteins [BR:lre01011]
 Precursor biosynthesis
  Amino acid ligase
   Lreu_0477
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp_4 ATP-grasp ATPgrasp_ST
Other DBs
NCBI-ProteinID: ABQ82745
UniProt: A5VIS1
Position
530114..531250
AA seq 378 aa
MTQKLHIALLFGGNSSEHDVSKRSAHNIYDALDKEKYDVSLFMFTKDGILLGNEDSQKIF
DGEPEDQVVAEAYQKMDMSSPLAPIMALNEQKEIDFFFPVIHGNLGEDGTIQGLFKLLNK
PYVGSNIAASAMSFDKDLTKKIISQAGIRNTPYVVVTPENQADYSWGRIEEKLGNLTFVK
PAKQGSSVGIHRVTNAEEYEKALDDAFKYDYKILVEQGIANPQEIEISILGNEHPIASKL
GAVRVPKDDPFYDYENKFVDASGVVFELPVKLPQYLVDEITDMALKAYKALGMKGMARID
FLVDSNNVPYLGEPNTLPGFTNISLYPQMWEVSGISYSDLIDRLIQLGLQEFERNSKIKY
DFRKLGTERVGQKKYNED
NT seq 1137 nt   +upstreamnt  +downstreamnt
atgacccaaaaattacacatcgctttattatttggtggcaactcctctgaacatgatgtg
tcaaagcgatcagcacataatatctatgatgctcttgataaggaaaagtatgatgtaagt
ctttttatgtttacaaaggatggaattctattaggcaatgaggattcccaaaagatcttt
gatggcgaacctgaagaccaagtggtagcggaagcatatcaaaagatggatatgagtagt
ccattagcaccaattatggccttaaacgaacaaaaggaaattgatttcttcttccctgtt
atccatggtaatttaggtgaagatggtacaattcaaggtctctttaagctccttaataag
ccatacgttggttcaaatattgcagctagtgcgatgtcttttgacaaggaccttactaag
aagattattagtcaagctggtattcgcaacaccccttatgtagtagttacgccagaaaac
caggctgactattcatggggacggattgaagaaaaattaggcaatctcacttttgtaaag
ccagctaagcaaggttcctccgttggaattcatcgagttactaacgctgaagaatacgaa
aaagcattagacgatgcctttaagtatgactacaagatcttagtagaacaaggaatcgct
aatcctcaagaaattgagatttcaatcttaggaaatgaacacccaattgcctctaagtta
ggagctgtacgtgtacctaaggatgatccattctatgattatgaaaacaaatttgtggat
gccagtggagttgtttttgaacttcctgttaaattaccacaatacttagttgatgaaatt
acagacatggctttgaaggcatacaaggcattaggaatgaaggggatggctcggattgac
tttttagttgacagcaataatgtcccttatcttggtgaaccaaatactttaccaggattt
actaacattagtttgtatcctcaaatgtgggaagtttctgggatttcatattccgacttg
attgatcggctaattcaattaggattacaagaatttgaacgaaacagtaagattaagtac
gatttccgtaagcttggtaccgaacgtgttggtcaaaagaaatataacgaagactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (6)   
   Pfam (6)   
All databases (26)   

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