KEGG   Lipotes vexillifer (Yangtze River dolphin): 103075499
Entry
103075499         CDS       T03090                                 

Gene name
ADCY4
Definition
(RefSeq) adenylate cyclase 4
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00230  Purine metabolism
lve01100  Metabolic pathways
lve01522  Endocrine resistance
lve04015  Rap1 signaling pathway
lve04020  Calcium signaling pathway
lve04022  cGMP-PKG signaling pathway
lve04024  cAMP signaling pathway
lve04062  Chemokine signaling pathway
lve04072  Phospholipase D signaling pathway
lve04114  Oocyte meiosis
lve04211  Longevity regulating pathway
lve04213  Longevity regulating pathway - multiple species
lve04261  Adrenergic signaling in cardiomyocytes
lve04270  Vascular smooth muscle contraction
lve04371  Apelin signaling pathway
lve04540  Gap junction
lve04611  Platelet activation
lve04713  Circadian entrainment
lve04714  Thermogenesis
lve04723  Retrograde endocannabinoid signaling
lve04724  Glutamatergic synapse
lve04725  Cholinergic synapse
lve04727  GABAergic synapse
lve04742  Taste transduction
lve04750  Inflammatory mediator regulation of TRP channels
lve04911  Insulin secretion
lve04912  GnRH signaling pathway
lve04913  Ovarian steroidogenesis
lve04914  Progesterone-mediated oocyte maturation
lve04915  Estrogen signaling pathway
lve04916  Melanogenesis
lve04918  Thyroid hormone synthesis
lve04921  Oxytocin signaling pathway
lve04923  Regulation of lipolysis in adipocytes
lve04925  Aldosterone synthesis and secretion
lve04926  Relaxin signaling pathway
lve04927  Cortisol synthesis and secretion
lve04928  Parathyroid hormone synthesis, secretion and action
lve04934  Cushing syndrome
lve04935  Growth hormone synthesis, secretion and action
lve04970  Salivary secretion
lve04971  Gastric acid secretion
lve04972  Pancreatic secretion
lve04976  Bile secretion
lve05032  Morphine addiction
lve05163  Human cytomegalovirus infection
lve05166  Human T-cell leukemia virus 1 infection
lve05200  Pathways in cancer
lve05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:lve00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    103075499 (ADCY4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    103075499 (ADCY4)
   04371 Apelin signaling pathway
    103075499 (ADCY4)
   04020 Calcium signaling pathway
    103075499 (ADCY4)
   04072 Phospholipase D signaling pathway
    103075499 (ADCY4)
   04024 cAMP signaling pathway
    103075499 (ADCY4)
   04022 cGMP-PKG signaling pathway
    103075499 (ADCY4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    103075499 (ADCY4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103075499 (ADCY4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103075499 (ADCY4)
   04062 Chemokine signaling pathway
    103075499 (ADCY4)
  09152 Endocrine system
   04911 Insulin secretion
    103075499 (ADCY4)
   04923 Regulation of lipolysis in adipocytes
    103075499 (ADCY4)
   04912 GnRH signaling pathway
    103075499 (ADCY4)
   04913 Ovarian steroidogenesis
    103075499 (ADCY4)
   04915 Estrogen signaling pathway
    103075499 (ADCY4)
   04914 Progesterone-mediated oocyte maturation
    103075499 (ADCY4)
   04921 Oxytocin signaling pathway
    103075499 (ADCY4)
   04926 Relaxin signaling pathway
    103075499 (ADCY4)
   04935 Growth hormone synthesis, secretion and action
    103075499 (ADCY4)
   04918 Thyroid hormone synthesis
    103075499 (ADCY4)
   04928 Parathyroid hormone synthesis, secretion and action
    103075499 (ADCY4)
   04916 Melanogenesis
    103075499 (ADCY4)
   04925 Aldosterone synthesis and secretion
    103075499 (ADCY4)
   04927 Cortisol synthesis and secretion
    103075499 (ADCY4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103075499 (ADCY4)
   04270 Vascular smooth muscle contraction
    103075499 (ADCY4)
  09154 Digestive system
   04970 Salivary secretion
    103075499 (ADCY4)
   04971 Gastric acid secretion
    103075499 (ADCY4)
   04972 Pancreatic secretion
    103075499 (ADCY4)
   04976 Bile secretion
    103075499 (ADCY4)
  09156 Nervous system
   04724 Glutamatergic synapse
    103075499 (ADCY4)
   04727 GABAergic synapse
    103075499 (ADCY4)
   04725 Cholinergic synapse
    103075499 (ADCY4)
   04723 Retrograde endocannabinoid signaling
    103075499 (ADCY4)
  09157 Sensory system
   04742 Taste transduction
    103075499 (ADCY4)
   04750 Inflammatory mediator regulation of TRP channels
    103075499 (ADCY4)
  09149 Aging
   04211 Longevity regulating pathway
    103075499 (ADCY4)
   04213 Longevity regulating pathway - multiple species
    103075499 (ADCY4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103075499 (ADCY4)
   04714 Thermogenesis
    103075499 (ADCY4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103075499 (ADCY4)
  09165 Substance dependence
   05032 Morphine addiction
    103075499 (ADCY4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    103075499 (ADCY4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103075499 (ADCY4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103075499 (ADCY4)
   05163 Human cytomegalovirus infection
    103075499 (ADCY4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103075499 (ADCY4)
Enzymes [BR:lve01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     103075499 (ADCY4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 103075499
NCBI-ProteinID: XP_007447961
UniProt: A0A340WGY9
Position
Un
AA seq 1073 aa
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLVGLLALLAVAWELASDPGFLTT
MLCGLGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGLGFLFTGGVVSAWDQVSFFL
FVIFTVYAMLPLGMRDAAAAGLASSLSHLLVLGLYLGPQPDSQPALLPQLAANAVLFLCG
NVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIM
ARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGK
FDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDIN
MRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAGAYAV
EDAAMEHGDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTRYLES
WGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTPRGLDDELDTGDAKFFQV
IEQLNSQKQWKQSEDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFFSNFIIQML
VTNRPPALTITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSVLVATRPGLRV
ALGTATILLVFSMAITSLVFLPAASNCPFLAPNVSSTASNLSWELPGSLPLISVPYSVHC
CVLGFLSCSLFLHTSFELKLLLLLLWLAACCSLFLHSHAWLSDCLIARLYLGALDSRPGL
LKEPKLMGAISFFVFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRLLLEN
VLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLRLLNE
IIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAEQSCSHLGTMVEFAV
ALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLG
KIQVTQETACALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG
NT seq 3222 nt   +upstreamnt  +downstreamnt
atggcccgcctcttcagtccccggccgcctcccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccactgctgctactgcttctggtgatcgtgctcgtcggg
ctcctggcgctgctcgctgttgcctgggagctggcctcagacccgggcttcctgaccact
atgctgtgcgggctgggcggcttctcgctgctgctgggcctggcttcccgcgagcagcga
ctgcagcgctggacgcgtcccctgtcgggcctcgtgtgggcagcgctgctcgcgctgggc
ctcggcttcctcttcactgggggcgtggtgagcgcctgggaccaggtgtcctttttcctt
tttgtcatcttcaccgtgtatgccatgttgcccttgggcatgcgggacgccgccgccgcg
ggtctcgcctcttcactctcacacctgctggtcctcgggctgtatcttgggcctcagccg
gactcacagcccgcgctcctgccacagctggcggcaaacgccgtgttgttcctgtgcggg
aacgtggctggagcataccacaaggcgctgatggagcgcgcgctgcgcgccacgttccgg
gaggcgcttagttccctgcactcccgccggaggctcgacacagagaagaagcaccaggaa
caccttctcttgtccatccttcctgcctacctggcccgagagatgaaggcggagatcatg
gcacggctgcaggccggacaggggtcacggccagagagcaccaacaacttccacagcctc
tatgtcaagaggcaccagggagtgagcgtgctgtatgctgacatcgtgggcttcacgcgg
ctggccagtgagtgctcccctaaggagttggtgctcatgctaaacgagctctttggcaag
ttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctgggagactgttac
tactgtgtctccgggctgccgctctcgctgccagaccatgccatcaactgcgtgcgcatg
gggctggacatgtgccgggccatcaggaagcttcgggcagccaccggcgtggatatcaac
atgcgtgtgggtgtgcactcgggcagcgtgctctgcggggtcatcgggctgcagaagtgg
cagtatgatgtctggtcccatgacgtcactctggccaaccacatggaggcgagtggagtg
ccaggacgagtacatatcacaggggctacgctggcactgctggcaggggcttacgctgtg
gaggatgcagccatggaacacggggacccatacctccgggagctaggggagccgacctac
cttgtcatcgatccccgggctgaggaggaggacgagaagggcactgcaggcgggttgctg
tcctctcttgagggccccaagatgcgtccatcactgttgatgacccgctacctggagtcc
tggggtgcagccaagcctttcgcccacctgagccatgtggagagccctgtgtccacctcc
acccctctcccggagaaggccctgtcttccttcagcccccagtggagcctggaccggagc
cgtaccccccggggactagatgatgaactagacaccggggatgccaagttcttccaagtc
atcgaacagctcaactctcagaaacagtggaaacagtcagaggacttcaacccattgacc
ctgtacttccgggagaaggagatggagaaagagtatcggctctctgcactccccgccttc
aaatactatgcagcctgcaccttcctggtttttttctccaacttcatcatccagatgctg
gtgacaaacaggcccccagctctgaccatcacctatagcatcaccttcctcctcttcttc
ctcctcctcttcgtctgcttctcagagcacctgacgaagtgtgtcttgaaaggccccaag
atgctgcactggctgcccacactgtctgtcctagtggccacacggcccggactgcgagtt
gccctgggcaccgctaccatcctgctcgtcttctccatggccattaccagcctggtcttc
ttaccggcagcatcaaactgccctttcctggctcccaatgtgtcctccacagcttccaac
ctctcctgggagctccctgggtccctgcctctcatcagcgtcccctactccgtgcactgc
tgcgtgctggggttcctctcctgctccctcttcctgcacacgagcttcgagctgaagctg
ctgctgctgctgctgtggctggcagcctgctgctccctcttcctgcactcccacgcctgg
ctgtccgactgtctcatcgcccgcctctatctgggcgccttggactccaggccagggctg
ctgaaggagcctaaactgatgggagcaatctccttctttgtcttcttcttcaccctcctg
gtcctggctcggcagaatgagtattactgccgcctggacttcctgtggaagaagaagctg
aggcaagagcaggaggagacagagacgatggaaaacctgactcggctgctcctggagaat
gtgctccccgcgcacgtagccccccagttcatcggccagaatcggcgcaacgaggacctc
taccaccagtcctacgagtgtgtttgtgtcctcttcgcctcagtcccagacttcaaggag
ttttactctgaatccagcatcaaccacgaggggctagagtgtctgcggctgctcaatgag
ataattgctgattttgatgagctgctctccaagcccaagttcagtggggtggagaaaatc
aaaactatctgcagcacctacatggcggctacaggcttgaacgccacctccggacaggac
gcacagcaggatgctgagcaaagctgcagccaccttggcaccatggtagagtttgccgtg
gcccttgggtctaagctggacgtcatcaacaagcactcattcaacaacttccgcttgcgt
gtggggttaaaccacggacctgtagtggccggagtgattggggcccagaaaccacaatat
gacatctggggcaacacggtgaacgtggccagccgaatggagagtacaggcgtcctgggc
aagatccaagtgacccaagagacagcctgcgccctgcagtccttaggctacacctgctac
agccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctacttcctgaacaca
gatttgacacgaactggacctccctcggccaccctaggctga

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