Entry |
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Name |
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Class |
Metabolism; Amino acid metabolism
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Pathway map |

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Module |
M00016 | Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:map00300] |
M00030 | Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:map00300] |
M00031 | Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine [PATH:map00300] |
M00433 | Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:map00300] |
M00525 | Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:map00300] |
M00526 | Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:map00300] |
M00527 | Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:map00300] |
M00608 | 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate [PATH:map00300] |
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Disease |
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Other DBs |
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Reference |
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Authors |
Ledwidge R, Blanchard JS. |
Title |
The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis. |
Journal |
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Reference |
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Authors |
Fuchs TM, Schneider B, Krumbach K, Eggeling L, Gross R. |
Title |
Characterization of a bordetella pertussis diaminopimelate (DAP) biosynthesis locus identifies dapC, a novel gene coding for an N-succinyl-L,L-DAP aminotransferase. |
Journal |
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Reference |
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Authors |
Zabriskie TM, Jackson MD. |
Title |
Lysine biosynthesis and metabolism in fungi. |
Journal |
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Reference |
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Authors |
Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS. |
Title |
Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch? |
Journal |
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Reference |
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Authors |
Velasco AM, Leguina JI, Lazcano A. |
Title |
Molecular evolution of the lysine biosynthetic pathways. |
Journal |
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Reference |
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Authors |
Miyazaki T, Miyazaki J, Yamane H, Nishiyama M. |
Title |
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus. |
Journal |
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Reference |
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Authors |
Goh DL, Patel A, Thomas GH, Salomons GS, Schor DS, Jakobs C, Geraghty MT. |
Title |
Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT). |
Journal |
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Reference |
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Authors |
Nishiyama M. |
Title |
[Novel lysine biosynthesis: a key to elucidate evolution of metabolic and biosynthetic pathways] |
Journal |
Tanpakushitsu Kakusan Koso 49:758-63 (2004) |
Reference |
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Authors |
Nishida H, Nishiyama M, Kobashi N, Kosuge T, Hoshino T, Yamane H. |
Title |
A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis. |
Journal |
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Reference |
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Authors |
Sakai H, Vassylyeva MN, Matsuura T, Sekine S, Gotoh K, Nishiyama M, Terada T, Shirouzu M, Kuramitsu S, Vassylyev DG, Yokoyama S. |
Title |
Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8. |
Journal |
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Reference |
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Authors |
Hudson AO, Singh BK, Leustek T, Gilvarg C. |
Title |
An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants. |
Journal |
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Reference |
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Authors |
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M |
Title |
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus. |
Journal |
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Reference |
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Authors |
Dairi T, Kuzuyama T, Nishiyama M, Fujii I |
Title |
Convergent strategies in biosynthesis. |
Journal |
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Reference |
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Authors |
Gaston MA, Jiang R, Krzycki JA |
Title |
Functional context, biosynthesis, and genetic encoding of pyrrolysine. |
Journal |
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Related pathway |
map00250 | Alanine, aspartate and glutamate metabolism |
map00260 | Glycine, serine and threonine metabolism |
map00960 | Tropane, piperidine and pyridine alkaloid biosynthesis |
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KO pathway |
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