Entry Name Lysine biosynthesis
Class Metabolism; Amino acid metabolismBRITE hierarchy
Pathway map Ortholog table Module M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:map00300 ]
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:map00300 ]
M00031 Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine [PATH:map00300 ]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:map00300 ]
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:map00300 ]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:map00300 ]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:map00300 ]
M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate [PATH:map00300 ]
Other DBs Reference Authors Ledwidge R, Blanchard JS.
Title The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis.
Journal Reference Authors Fuchs TM, Schneider B, Krumbach K, Eggeling L, Gross R.
Title Characterization of a bordetella pertussis diaminopimelate (DAP) biosynthesis locus identifies dapC, a novel gene coding for an N-succinyl-L,L-DAP aminotransferase.
Journal Reference Authors Zabriskie TM, Jackson MD.
Title Lysine biosynthesis and metabolism in fungi.
Journal Reference Authors Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS.
Title Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch?
Journal Reference Authors Velasco AM, Leguina JI, Lazcano A.
Title Molecular evolution of the lysine biosynthetic pathways.
Journal Reference Authors Miyazaki T, Miyazaki J, Yamane H, Nishiyama M.
Title alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.
Journal Reference Authors Goh DL, Patel A, Thomas GH, Salomons GS, Schor DS, Jakobs C, Geraghty MT.
Title Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT).
Journal Reference Authors Nishiyama M.
Title [Novel lysine biosynthesis: a key to elucidate evolution of metabolic and biosynthetic pathways]
Journal Tanpakushitsu Kakusan Koso 49:758-63 (2004)
Reference Authors Nishida H, Nishiyama M, Kobashi N, Kosuge T, Hoshino T, Yamane H.
Title A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis.
Journal Reference Authors Sakai H, Vassylyeva MN, Matsuura T, Sekine S, Gotoh K, Nishiyama M, Terada T, Shirouzu M, Kuramitsu S, Vassylyev DG, Yokoyama S.
Title Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8.
Journal Reference Authors Hudson AO, Singh BK, Leustek T, Gilvarg C.
Title An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants.
Journal Reference Authors Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
Title Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
Journal Reference Authors Dairi T, Kuzuyama T, Nishiyama M, Fujii I
Title Convergent strategies in biosynthesis.
Journal Reference Authors Gaston MA, Jiang R, Krzycki JA
Title Functional context, biosynthesis, and genetic encoding of pyrrolysine.
Journal Related map00250 Alanine, aspartate and glutamate metabolism
map00260 Glycine, serine and threonine metabolism
map00960 Tropane, piperidine and pyridine alkaloid biosynthesis
KO pathway
