KEGG   PATHWAY: map00514
Entry
map00514                    Pathway                                

Name
Other types of O-glycan biosynthesis
Description
O-linked glycosylation is the attachment of monosaccharides to the hydroxyl groups of amino acids, mostly serine and threonine, and is found in eukaryotes, archaea and bacteria. O-glycans exhibit diverse types of modifications where the innermost monosaccharide is N-acetylgalactosamine (map00512), mannose in mammals (map00515), and others (this map) including N-acetylglucosamine, fucose, glucose, galactose, mannose in yeast and arabinose in plants.
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
map00514  Other types of O-glycan biosynthesis
map00514

Disease
H00593  Limb-girdle muscular dystrophy
H00944  Dowling-Degos disease
H01192  Lysyl hydroxylase 3 deficiency
Reference
  Authors
Kizuka Y, Oka S
  Title
Regulated expression and neural functions of human natural killer-1 (HNK-1) carbohydrate.
  Journal
Cell Mol Life Sci 69:4135-47 (2012)
DOI:10.1007/s00018-012-1036-z
Reference
  Authors
Lommel M, Strahl S
  Title
Protein O-mannosylation: conserved from bacteria to humans.
  Journal
Glycobiology 19:816-28 (2009)
DOI:10.1093/glycob/cwp066
KO pathway
ko00514   

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