Entry
Name
Arachidonic acid metabolism
Class
Metabolism; Lipid metabolism
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Pathway map
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Reference
Authors
Spector AA, Fang X, Snyder GD, Weintraub NL.
Title
Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function.
Journal
Reference
Authors
Harman CA, Rieke CJ, Garavito RM, Smith WL.
Title
Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid.
Journal
Reference
Authors
Poloyac SM, Tortorici MA, Przychodzin DI, Reynolds RB, Xie W, Frye RF, Zemaitis MA.
Title
The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney.
Journal
Reference
Authors
Chuang SS, Helvig C, Taimi M, Ramshaw HA, Collop AH, Amad M, White JA, Petkovich M, Jones G, Korczak B.
Title
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids.
Journal
Reference
Authors
Sacerdoti D, Gatta A, McGiff JC.
Title
Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology.
Journal
Reference
Authors
Pfister SL, Spitzbarth N, Zeldin DC, Lafite P, Mansuy D, Campbell WB.
Title
Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.
Journal
Reference
Authors
Fleming I.
Title
Cytochrome p450 and vascular homeostasis.
Journal
Reference
Authors
Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL, Zeldin DC.
Title
Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain.
Journal
Reference
Authors
Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC, Goldstein JA.
Title
CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract.
Journal
Reference
Authors
Pfister SL, Spitzbarth N, Nithipatikom K, Edgemond WS, Falck JR, Campbell WB.
Title
Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta.
Journal
Related pathway
KO pathway