KEGG   PATHWAY: map00945
Entry
map00945                    Pathway                                

Name
Stilbenoid, diarylheptanoid and gingerol biosynthesis
Description
Stilbenoids are a group of phenolic compounds, biosynthetically interrelated through their common origin from a C6-C2-C6 intermediate, such as resveratol found in grapes. Stilbenoids can also exist as glycosides (e.g., piceid). Combretastatins are potentially useful stilbenoid natural products with known antitumor activity. Diarylheptanoid is a compound group having phenyl rings at 1,7 positions of n-heptane (C6-C7-C6), such as curcumin found in the ginger family. [6]-Gingerol is a major active component of ginger and has diverse pharmacologic effects.
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
map00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
map00945

Reference
  Authors
Katsuyama Y, Kita T, Funa N, Horinouchi S
  Title
Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.
  Journal
J Biol Chem 284:11160-70 (2009)
DOI:10.1074/jbc.M900070200
Reference
  Authors
Ramirez-Ahumada Mdel C, Timmermann BN, Gang DR
  Title
Biosynthesis of curcuminoids and gingerols in turmeric (Curcuma longa) and ginger (Zingiber officinale): identification of curcuminoid synthase and hydroxycinnamoyl-CoA thioesterases.
  Journal
Phytochemistry 67:2017-29 (2006)
DOI:10.1016/j.phytochem.2006.06.028
Reference
  Authors
Masada S, Terasaka K, Mizukami H
  Title
A single amino acid in the PSPG-box plays an important role in the catalytic function of CaUGT2 (Curcumin glucosyltransferase), a Group D Family 1 glucosyltransferase from Catharanthus roseus.
  Journal
FEBS Lett 581:2605-10 (2007)
DOI:10.1016/j.febslet.2007.05.002
Related
pathway
map00940  Phenylpropanoid biosynthesis
KO pathway
ko00945   

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