KEGG   Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2: BCG_2141c
Entry
BCG_2141c         CDS       T00463                                 
Symbol
metH
Name
(GenBank) Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mbb  Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2
Pathway
mbb00270  Cysteine and methionine metabolism
mbb00450  Selenocompound metabolism
mbb00670  One carbon pool by folate
mbb01100  Metabolic pathways
mbb01110  Biosynthesis of secondary metabolites
mbb01230  Biosynthesis of amino acids
mbb04980  Cobalamin transport and metabolism
Module
mbb_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mbb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    BCG_2141c (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    BCG_2141c (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    BCG_2141c (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    BCG_2141c (metH)
Enzymes [BR:mbb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     BCG_2141c (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Na_Ca_ex_C HTH_39
Other DBs
NCBI-ProteinID: CAL72129
UniProt: A0A0H3M6G7
Position
complement(2362499..2366077)
AA seq 1192 aa
MTAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
ETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRK
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGT
TPAHIREVAAAVANIKRPERQVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFRE
AMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
ETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRH
PDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNV
ALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAGLPLFERLAQRIVDGERNGL
DADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIVLSNNGYEVVNIGIKQPIATILEVAEDKS
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVH
YARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAERKARHQRSKRIAAQRKAAEE
PVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRY
RFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRD
YLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPEAKEDYFKLGYRGARFAFGY
GACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq 3579 nt   +upstreamnt  +downstreamnt
gtgactgcggccgacaagcacctctacgacaccgatctgctcgacgtcttgtcgcagcga
gtgatggtcggcgacggtgcaatgggaacccaactacaggccgcggacctcacgctcgac
gacttccgcggcctggagggctgcaacgagatcctcaacgaaacccgccctgacgtgctg
gaaaccattcaccgcaactatttcgaagcgggcgccgacgccgtcgagacgaacacgttt
ggctgcaacctgtccaacctcggcgactacgacatcgccgacaggatccgcgatctatca
cagaagggcaccgcgatcgcacgccgggtggccgacgagctgggcagtcccgaccgcaag
cgctacgtgctggggtcgatggggccgggcaccaagctgccgactctgggccacaccgaa
tacgcggtgatccgcgacgcctacaccgaggccgcgctgggcatgctggacggcggagcc
gacgccatcctggtggaaacctgccaggacctactgcagctgaaggcggcggtgttgggg
tcgcggcgggcgatgacgcgggccgggcggcacattccggtgtttgcccacgtcaccgtc
gagaccaccggcaccatgctgctgggcagcgagatcggggcggcgttgaccgctgtcgag
ccgctcggtgtggacatgatcggcttgaactgcgcgacgggtccggccgagatgagcgag
cacctgcgccacctgtcccggcacgcccgcatcccggtgtcggtgatgcccaacgccggg
ttgccggtgctgggcgccaagggcgccgaatatccgttgctgcccgacgaattggccgag
gcgctggccggcttcatcgccgagttcgggctctcgctggtcggtggctgctgcggcacc
accccggcccatatccgcgaagtggctgccgcggttgcgaacatcaagcgtcccgagcga
caggtcagctacgagccgtcggtgtcgtcgctgtacaccgcaatcccgttcgcccaggac
gcctcggttcttgtgatcggggagcgaacgaacgccaacggctccaagggttttcgtgag
gcgatgatcgccgaggactaccagaagtgcctggacatcgccaaggaccagacccgcgac
ggcgcccacctgctggacctgtgtgtggactacgtgggccgcgacggtgtggccgacatg
aaggcgctggccagccggctggccacgtcctcgacgctgccgatcatgctggactccacc
gaaaccgcggtgctgcaggcgggtttggagcatctgggtggccggtgcgcgatcaactcg
gtgaactacgaggacggcgacggcccggaatcgcgctttgccaagaccatggcgctggtc
gccgagcacggcgcggcggtggtcgcgctgaccatcgacgaagagggccaggcccgcacc
gcgcagaagaaggtcgagatcgccgagcggctgatcaacgacatcaccggcaactggggc
gtcgacgaatcatccatcctcatcgacaccttgacgttcaccatcgccaccggtcaggag
gagtcccgccgcgacggcatcgagaccatcgaggcgatccgcgaactgaaaaagcgccac
ccggatgtgcagaccacacttggtctgtccaacatctcgtttggtctcaatcccgcagcg
cgccaggtgctcaactcggtgttcctgcacgaatgccaagaagcggggctggattcggcg
atcgtgcacgcgtcgaagatcctgccgatgaaccggattcccgaggagcaacgcaacgtc
gccctggatctggtctacgaccgccgccgcgaggactacgatccgctgcaggagctgatg
cggctgttcgaaggcgtgtcggcggcctcctcgaaagaggaccgactggctgaactagct
gggctgccgctgttcgaacggctggcccaacgcatcgtcgacggcgagcgcaacggcctg
gacgccgatctcgacgaggcgatgacgcaaaagccgccgcttcagatcatcaacgaacat
ctgctggccggcatgaagacggtcggcgagctcttcggctccggccagatgcagctgccg
ttcgtgctgcagtcggcggaggtaatgaaagccgccgtcgcgtatctggaaccgcacatg
gagcgctcggacgacgattcgggcaagggacgcatcgtgctggccaccgtcaagggcgac
gtgcacgacatcggcaagaacctggtcgacatcgtcttgagcaacaacggctacgaagtg
gtcaacatcggcatcaagcagccaatcgccaccatcctcgaagtcgccgaggacaagagc
gccgacgtggtcggcatgtcgggcctgctggtgaagtcgaccgtggtgatgaaggaaaac
ctcgaggagatgaacacccggggagtcgccgaaaagttcccggtgctgctcggcggcgcg
gcgttgacgcgcagctatgtcgaaaacgacctggccgagatctaccagggcgaagtgcat
tacgcgcgagacgctttcgagggcctgaagttgatggacaccatcatgagcgccaagcgc
ggcgaggcgcccgacgaaaacagcccggaagccattaaggcgcgtgagaaagaagccgaa
cgtaaggcccgccaccagcgatccaaacgcattgccgcacagcgcaaagccgccgaagaa
ccagtcgaggtgcccgaacgctccgatgtcgcggccgacatcgaggtcccggcgccgccg
ttctggggttcgcggatcgtcaagggcctggcggtggccgactacaccggtctgctcgat
gagcgcgcattgtttttgggccagtggggtttacgcggccagcgcggcggtgagggtccg
tcctacgaagatctcgtcgagaccgagggccggccgcggctgcggtactggttggaccgg
ctgtccaccgacggcatcttggcgcacgccgccgtggtgtacggctatttcccggcggtg
tccgagggcaacgacatcgtggtgctcaccgagcccaagcccgacgccccggtgcgctac
cggtttcacttcccgcgccagcagcgcggtcggtttttgtgcattgccgatttcatccgc
tcgcgggagctggccgccgagcgtggcgaggttgacgtgctgccgttccagctggtgacc
atgggtcagccgatcgcggatttcgccaacgagctgttcgcgtccaacgcctaccgcgac
tacctggaggtgcacggtatcggcgtgcagctcaccgaggcgctggccgagtactggcac
cggcggatccgtgaggagctcaagttctccggggatcgggcgatggcggccgaggatccg
gaggcgaaagaagactatttcaagctcggctaccgcggtgctcgctttgccttcggctac
ggcgcatgcccggatctggaggaccgcgccaagatgatggcgctgctggagcccgaacgc
atcggtgtgacgttatccgaggaattacagctgcatcccgaacagtcgaccgacgcgttc
gtcctgcaccatccggaagccaagtacttcaacgtttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (7)   
   Pfam (7)   
All databases (33)   

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