KEGG   Mus caroli (Ryukyu mouse): 110291001
Entry
110291001         CDS       T05910                                 
Symbol
Pde5a
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
  KO
K13762  cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal00230  Purine metabolism
mcal01100  Metabolic pathways
mcal04022  cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    110291001 (Pde5a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    110291001 (Pde5a)
Enzymes [BR:mcal01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     110291001 (Pde5a)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2
Other DBs
NCBI-GeneID: 110291001
NCBI-ProteinID: XP_021013597
Ensembl: MGP_CAROLIEiJ_G0025596
UniProt: A0A6P5PDY2
Position
3:116257741..116382694
AA seq 865 aa
MERAGPSSVRSQQQRDPDWVEAWLDDHRDFTFSYFVRKATRDMVNAWFSERVHNIPVCKE
GMRAHTESCSCSLQQSPHADNTTPGAPARKISASEFDRPLRPIVVKDSEGTVSFLSDSGK
KEQMPLTPPRFDSDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSKDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCPDSFSRVFHMECEEVGRPSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKD
KRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQG
DRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNR
QKWQALAEQQEKMLLNGESSQGKRE
NT seq 2598 nt   +upstreamnt  +downstreamnt
atggaacgagcgggccccagctccgttcggtcgcagcagcagcgggacccggactgggtg
gaagcgtggctggatgatcaccgggactttaccttctcttactttgttagaaaggccacc
agagacatggtcaacgcatggttttcagagagagttcacaacatccctgtgtgtaaggaa
ggcatgcgagcccataccgagtcctgctcttgctctctgcagcaaagtcctcatgcagat
aataccacccctggagcaccagccagaaaaatatctgcctctgaatttgaccgacctctt
agacccattgttgtcaaggattccgagggaacagtgagctttctctctgactcaggaaaa
aaggagcagatgccactaaccccgccaagatttgatagtgatgaaggggaccagtgctca
agactcttggagctagtaaaagatatatccagtcatttggatgtcacagcattgtgccac
aaaattttcttgcatatccatggactcatctctgcggatcgctattccctgttccttgtc
tgcgaggacagctctaaagacaaattcctcatcagccgcctctttgatgttgctgaaggt
tcaacactggaggaagcttcaaataactgtatccgtttagagtggaacaaaggcattgtg
ggacatgtggcagcttttggtgagcccttgaacatcaaagatgcctatgaggatccccgg
ttcaatgcagaagttgaccaaattacaggctacaagacacaaagtatcctttgtatgcca
attaagaaccacagggaagaggttgttggtgtagctcaggccatcaacaagaaatcagga
aatggtgggaccttcactgaaaaagatgaaaaggactttgcggcctacctggcattctgt
ggtattgttcttcacaatgctcagctctacgaaacgtcgctgctggagaacaaaagaaat
caggtgttacttgaccttgcgagcttaatctttgaagagcagcagtccctggaagtcatt
ctgaagaagatcgctgccactatcatctccttcatgcaggtgcagaagtgcaccatcttc
attgtggatgaagactgtcctgactctttctctcgtgtgtttcacatggagtgtgaggaa
gtagggagaccctccgatcctttaacgagggagcaagatgcaaacaaaatcaactacatg
tatgcccagtatgtcaaaaacacgatggagccacttaatatcccagatgtcaccaaggac
aaaagatttccctggacaaatgaaaacatgggacacgtgaacacgccctgcattggaagt
ttactttgcacccctataaaaaacgggaagaagaacaaagtcataggcgtttgccaactt
gttaataagatggaggagaatactggcaagattaaagctttcaaccaaaatgatgagcag
ttcctggaagcctttgtcatcttctgtggcttggggatccagaacacacagatgtatgaa
gcagtggagagagccatggccaagcagatggtgacattagaggtcctgtcttaccatgca
tcagcggcggaggaagaaacaagagagctccaggctttatcggctgctgtggtaccatcg
gcccaaacccttaaaattaccgacttcagcttcagtgactttgagctgtctgatctggaa
acagcactgtgtacaattcggatgttcactgacctcaaccttgtgcagaatttccagatg
aaacatgaggttctttgcaggtggattttaagtgtgaagaagaattatcggaagaacgtt
gcctaccacaattggaggcatgcctttaacacggcacagtgcatgtttgctgctctgaaa
gccggcaagatccagaacaagttgacggatctggagatccttgcgttgctgattgctgct
ttaagccatgacttggatcatcgtggcgtgaacaactcatacatacagcggagcgagcac
ccgctggctcagctgtactgtcactccatcatggaacaccatcattttgaccagtgtttg
atgattctaaacagcccaggcaaccagattctcagtggcctctccattgaagaatataaa
accacattgaaaataatcaagcaagcaattttagccacagacctagcactgtacattaag
agacgaggagaattttttgaacttatacgaaaaaatcaattcagttttgaagatcctctt
caaaaggagttgtttctagcaatgctgatgacagcctgcgacctctctgcgattactaaa
ccctggcctattcaacaacggatagcagaactcgtggcagctgaattctttgaccaagga
gacagagagagaaaagaactgaacatggagccggctgatctaatgaacagagagaagaaa
aacaaaatcccaagtatgcaagttgggttcatagatgccatctgcttgcagctgtatgag
gccctgacccacgtatccgaagactgtttgcccttgctggatggctgcaggaagaacaga
cagaaatggcaggccctggcggagcagcaggagaagatgctccttaacggggagagcagc
cagggcaagcgggaatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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