KEGG   Mus caroli (Ryukyu mouse): 110309267
Entry
110309267         CDS       T05910                                 

Gene name
Adcy4
Definition
(RefSeq) adenylate cyclase type 4
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal00230  Purine metabolism
mcal01100  Metabolic pathways
mcal01522  Endocrine resistance
mcal04015  Rap1 signaling pathway
mcal04020  Calcium signaling pathway
mcal04022  cGMP-PKG signaling pathway
mcal04024  cAMP signaling pathway
mcal04062  Chemokine signaling pathway
mcal04072  Phospholipase D signaling pathway
mcal04114  Oocyte meiosis
mcal04211  Longevity regulating pathway
mcal04213  Longevity regulating pathway - multiple species
mcal04261  Adrenergic signaling in cardiomyocytes
mcal04270  Vascular smooth muscle contraction
mcal04371  Apelin signaling pathway
mcal04540  Gap junction
mcal04611  Platelet activation
mcal04713  Circadian entrainment
mcal04714  Thermogenesis
mcal04723  Retrograde endocannabinoid signaling
mcal04724  Glutamatergic synapse
mcal04725  Cholinergic synapse
mcal04727  GABAergic synapse
mcal04742  Taste transduction
mcal04750  Inflammatory mediator regulation of TRP channels
mcal04911  Insulin secretion
mcal04912  GnRH signaling pathway
mcal04913  Ovarian steroidogenesis
mcal04914  Progesterone-mediated oocyte maturation
mcal04915  Estrogen signaling pathway
mcal04916  Melanogenesis
mcal04918  Thyroid hormone synthesis
mcal04921  Oxytocin signaling pathway
mcal04923  Regulation of lipolysis in adipocytes
mcal04925  Aldosterone synthesis and secretion
mcal04926  Relaxin signaling pathway
mcal04927  Cortisol synthesis and secretion
mcal04928  Parathyroid hormone synthesis, secretion and action
mcal04934  Cushing syndrome
mcal04935  Growth hormone synthesis, secretion and action
mcal04970  Salivary secretion
mcal04971  Gastric acid secretion
mcal04972  Pancreatic secretion
mcal04976  Bile secretion
mcal05032  Morphine addiction
mcal05163  Human cytomegalovirus infection
mcal05166  Human T-cell leukemia virus 1 infection
mcal05200  Pathways in cancer
mcal05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    110309267 (Adcy4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    110309267 (Adcy4)
   04371 Apelin signaling pathway
    110309267 (Adcy4)
   04020 Calcium signaling pathway
    110309267 (Adcy4)
   04072 Phospholipase D signaling pathway
    110309267 (Adcy4)
   04024 cAMP signaling pathway
    110309267 (Adcy4)
   04022 cGMP-PKG signaling pathway
    110309267 (Adcy4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    110309267 (Adcy4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    110309267 (Adcy4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110309267 (Adcy4)
   04062 Chemokine signaling pathway
    110309267 (Adcy4)
  09152 Endocrine system
   04911 Insulin secretion
    110309267 (Adcy4)
   04923 Regulation of lipolysis in adipocytes
    110309267 (Adcy4)
   04912 GnRH signaling pathway
    110309267 (Adcy4)
   04913 Ovarian steroidogenesis
    110309267 (Adcy4)
   04915 Estrogen signaling pathway
    110309267 (Adcy4)
   04914 Progesterone-mediated oocyte maturation
    110309267 (Adcy4)
   04921 Oxytocin signaling pathway
    110309267 (Adcy4)
   04926 Relaxin signaling pathway
    110309267 (Adcy4)
   04935 Growth hormone synthesis, secretion and action
    110309267 (Adcy4)
   04918 Thyroid hormone synthesis
    110309267 (Adcy4)
   04928 Parathyroid hormone synthesis, secretion and action
    110309267 (Adcy4)
   04916 Melanogenesis
    110309267 (Adcy4)
   04925 Aldosterone synthesis and secretion
    110309267 (Adcy4)
   04927 Cortisol synthesis and secretion
    110309267 (Adcy4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110309267 (Adcy4)
   04270 Vascular smooth muscle contraction
    110309267 (Adcy4)
  09154 Digestive system
   04970 Salivary secretion
    110309267 (Adcy4)
   04971 Gastric acid secretion
    110309267 (Adcy4)
   04972 Pancreatic secretion
    110309267 (Adcy4)
   04976 Bile secretion
    110309267 (Adcy4)
  09156 Nervous system
   04724 Glutamatergic synapse
    110309267 (Adcy4)
   04727 GABAergic synapse
    110309267 (Adcy4)
   04725 Cholinergic synapse
    110309267 (Adcy4)
   04723 Retrograde endocannabinoid signaling
    110309267 (Adcy4)
  09157 Sensory system
   04742 Taste transduction
    110309267 (Adcy4)
   04750 Inflammatory mediator regulation of TRP channels
    110309267 (Adcy4)
  09149 Aging
   04211 Longevity regulating pathway
    110309267 (Adcy4)
   04213 Longevity regulating pathway - multiple species
    110309267 (Adcy4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    110309267 (Adcy4)
   04714 Thermogenesis
    110309267 (Adcy4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110309267 (Adcy4)
  09165 Substance dependence
   05032 Morphine addiction
    110309267 (Adcy4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    110309267 (Adcy4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110309267 (Adcy4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110309267 (Adcy4)
   05163 Human cytomegalovirus infection
    110309267 (Adcy4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    110309267 (Adcy4)
Enzymes [BR:mcal01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     110309267 (Adcy4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 110309267
NCBI-ProteinID: XP_021037475
Ensembl: MGP_CAROLIEiJ_G0019319
Position
14
AA seq 1077 aa
MARLFSPRPPPSEDLFYETYYSLSQQYPLLILLLVIVLCALVALPAVAWASGRELTSDPS
FLTTVLCALGGFSLLLGLASREQQLQRWTRPLSGLIWVALLALGYGFLFTGGVVSAWDQV
SFFLFIIFTVYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWQPESQRALLPQLAANAVL
FLCGNLVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQHSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVERADTEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAKGLLSSLEGHTMRPSLLMTR
YLESWGAAKPFAHLSHLDCPVSTSTPLPEKAFSPQWSLDRSRTPRGLDDELDTGDAKFFQ
VIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQM
LVTTRPPALIITYSITFLLFFLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGFR
VALGTATILLVFTMAIASLLFLPVSSDCLFLASNVSSVTFNASWEMPGSLPLISIPLISI
PYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYQSPS
DSRPGVLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLT
RLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLEC
LRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDAERSCSHLGT
MVEFAVALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRME
STGVLGKIQVTEETARALQSLGYTCYSRGSIKVKGKGELYTYFLNTDLTRTGSPSAS
NT seq 3234 nt   +upstreamnt  +downstreamnt
atggcccgcctcttcagtccccggcctcctcccagcgaagatctcttctacgaaacttac
tacagcctgagccaacagtacccactgctgatactgcttttggtcattgtgctctgcgcg
ctggtggcactgcccgccgtcgcctgggccagcggcagggagctgacctcagacccaagc
ttcctgacaactgtgctgtgtgctttgggtggcttctctctgctattggggctcgcttcc
cgggagcagcaactgcagcgatggacacgacctctttctggtctcatatgggttgcattg
ctggctttgggctatggatttctgttcactgggggtgtggtgagtgcctgggaccaggtg
tcttttttcctcttcatcatcttcaccgtgtacgccatgctgcccttgggcatgcgggat
gctgctgctgcgggggtcatctcatccctctctcacctgctggtccttggactgtatctt
gggtggcagcctgagtcacagagagctctgctaccacagttggcagcaaacgcggtgttg
ttcctgtgtgggaacctggtgggggcgtaccacaaggccctgatggagcgagcattgcgg
gccacgttccgggaggctcttagctctctgcactcacgccggaggctggacactgagaaa
aagcaccaggagcacctcctcttgtccatccttcctgcctacctggcccgagagatgaaa
gcagagatcatggcccggctgcaggctggacagcactcacggccagagaacacaaacaac
tttcacagcctgtacgtcaagaggcaccaaggagtgagtgtgctgtatgctgacatcgtg
ggcttcacgcggctggccagtgagtgttccccaaaggagctggtgctcatgctgaatgag
ctctttggcaagttcgaccagattgccaaggagcacgaatgcatgcggatcaagatcctg
ggagactgttactactgtgtgtccgggctgcccctctcgctgcctgaccacgctatcaat
tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggtagccaccggt
gtggatatcaacatgcgcgtgggcgtgcactcgggcagcgttctctgtggagtcatcggg
ctacagaagtggcagtatgatgtctggtcccatgatgtcacattggccaaccatatggaa
gcagggggtgtaccaggacgagtgcacatcacaggggccacactggccctgctagcagga
gcttatgctgtggaaagggcagacacggaacaccgagacccgtaccttcgggagctaggc
gaacctacatacctggtcattgaccctcgggctgaggaggaagacgagaagggcaccgca
aaaggattgctgtcttctctggaggggcacacgatgcgtccgtcacttctgatgactcgc
tatctggagtcttggggtgcagccaagcctttcgcccacctaagccaccttgactgtcct
gtgtctacctccactccactaccggagaaagccttcagcccccagtggagcctggaccgg
agtcgcaccccccggggactagatgatgagctggacactggtgatgccaagttcttccag
gtcatcgaacaactcaactctcagaaacagtggaagcagtcgaaggacttcaacctcctg
acgctgtacttcagagagaaggagatggagaaacagtatcggctctctgcacttccagcg
ttcaaatactacgcagcctgcaccttcctggtttttctgtccaacttcactatccaaatg
ctggtgacaaccaggcccccagctctgatcatcacctacagcatcaccttccttctcttc
tttctcctcctcttcgtctgcttctcagagcacctgacgaagtgtgtccagaaaggtccc
aagatgttgcactggctgcctgcactgtctgtcctggtggccacacggccaggatttcga
gtagccctgggcacggccaccatcctcctagtattcactatggccatcgccagcctgctc
ttcttaccagtgtcatcagactgccttttcctggcttccaatgtgtcgtctgtgactttc
aatgcttcctgggagatgccaggatccctgcccctcatcagcatccccctcatcagcatc
ccatactccatgcattgctgcgtgttgggtttcctctcctgctccctttttctgcacatg
agcttcgaactgaagctgctcctacttctgctgtggctggtggcatcttgttccctattt
ctgcattcccacgcctggctgtccgactgcctcattgcccgcctttatcaaagcccttca
gactccaggccaggggtgctgaaggaacccaagctgatgggagctatctacttcttcatc
ttcttcttcacactcctggtcctggctcggcagaatgagtattactgccgcctggacttc
ctgtggaaaaagaaactgaggcaggagcgagaggagactgagacgatggagaacctgacc
cggctcctcctggagaatgtactccctgcacacgtggccccccagttcatcggccagaac
cggcgcaatgaggacctctaccaccagtcgtacgaatgcgtgtgtgtcctcttcgcatcg
gtcccagactttaaggaattctactctgaatccaacatcaaccacgaggggctggagtgc
ctgcggctgctcaatgagatcatcgctgactttgatgagctgctctccaagccaaagttc
agtggagtagaaaagatcaaaactattggcagtacctacatggcagccacaggcttaaat
gccacctctggacaggatactcaacaggatgctgagagaagctgcagtcatctgggcacc
atggtggaatttgcagtggccctggggtctaagctgggtgtcatcaacaagcactcgttc
aacaacttccgcctgcgtgtggggttgaaccacggaccagtagtagcaggggtgattggg
gcgcagaagccacagtatgacatctgggggaacacagtgaatgtggccagccgcatggag
agcacaggcgttctcggcaagatccaagtgactgaggagacagcgcgggccctgcagtct
ctgggttacacatgctatagcagaggcagcatcaaggtcaaaggcaaaggggaactctat
acctacttcctgaacacagacctgacgcggaccggatctccctcagcatcctag

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