KEGG   Macaca mulatta (rhesus monkey): 2846630
Entry
2846630           CDS       T01028                                 
Symbol
ND4
Name
(RefSeq) NADH dehydrogenase subunit 4
  KO
K03881  NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc00190  Oxidative phosphorylation
mcc01100  Metabolic pathways
mcc04714  Thermogenesis
mcc04723  Retrograde endocannabinoid signaling
mcc05010  Alzheimer disease
mcc05012  Parkinson disease
mcc05014  Amyotrophic lateral sclerosis
mcc05016  Huntington disease
mcc05020  Prion disease
mcc05022  Pathways of neurodegeneration - multiple diseases
mcc05208  Chemical carcinogenesis - reactive oxygen species
mcc05415  Diabetic cardiomyopathy
Module
mcc_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    2846630 (ND4)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    2846630 (ND4)
  09159 Environmental adaptation
   04714 Thermogenesis
    2846630 (ND4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    2846630 (ND4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    2846630 (ND4)
   05012 Parkinson disease
    2846630 (ND4)
   05014 Amyotrophic lateral sclerosis
    2846630 (ND4)
   05016 Huntington disease
    2846630 (ND4)
   05020 Prion disease
    2846630 (ND4)
   05022 Pathways of neurodegeneration - multiple diseases
    2846630 (ND4)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    2846630 (ND4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:mcc03029]
    2846630 (ND4)
Enzymes [BR:mcc01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     2846630 (ND4)
Mitochondrial biogenesis [BR:mcc03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    2846630 (ND4)
SSDB
Motif
Pfam: Proton_antipo_M Oxidored_q5_N
Other DBs
NCBI-GeneID: 2846630
NCBI-ProteinID: YP_026113
UniProt: Q6IYG9
Position
MT:10751..12128
AA seq 459 aa
MLKMIIPTTMLLPMTWLSKNNTIWINLTMHSLTISLIPLLFFNQTSTNLLNHSTYLSSDP
LAAPLLTLTIWLLPLMIMASQYHLYNEPPSQKKLFLFTMILLQITLILTFMATELIMFYI
LFETTLIPTLIIITKWGNQAKRLNASTYFLFYTLTGSLPLLIMLSHTYNNTGSLNITLLT
LTDQKLTTTWSHNFTWLACMMAFMTKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGG
YGMMRLTPILNPLTEYMAYPFLMLSLWGMIMTGLTCLRQTDLKSLIAYSSVSHMALVIVA
SLIQTPWSFSGATILMIAHGLTSSMYFCLANSNYERTHSRTMLLSRGLQILLPLTAFWWL
TASLTNLALPPTINLLGELFVITTSFSWSHITIMLTGLNMLITALYSLHMFITTQRGMLT
HHMINMKPSFTRENMLMFMHLAPIILLSLNPNIILGFTS
NT seq 1378 nt   +upstreamnt  +downstreamnt
atgctaaaaataattattcccacaaccatactactacccataacatgactctctaaaaat
aatacaatttgaatcaacttgaccatgcatagcttaactatcagcctcatccccttacta
ttcttcaaccaaaccagcaccaacctcctcaatcactcaacctatctatcttctgaccca
ctagcagcacccctcctaacactaactatctgacttctacccctcatgattatagcgagc
cagtatcacctatataacgaacccccctcacaaaaaaaacttttcctcttcacaataatt
ctcctacaaatcaccctaattctgacattcatggccacagagctaattatattctacatt
ctatttgaaaccaccctaattcccaccctaattatcattactaaatggggcaaccaagca
aaacgcctcaacgcaagtacctactttctattctatacactaaccggctctctaccccta
ctcatcatactaagccacacctacaacaacacaggctcattaaatattacattactaaca
ctcacagaccaaaaactaacaaccacctgatctcacaactttacctgactagcatgcata
atagcctttatgacaaaaatacccctatatggcctacacctgtgacttcctaaagcccat
gtcgaagcccccattgcaggatcaatagtccttgccgcagtactcctaaaactaggtggc
tacggcataatacgacttactcccatccttaaccccttaacagaatacatagcttaccca
ttcctcatattatccttatggggtataatcataacaggcctaacatgcctccgacaaaca
gatctaaaatcacttatcgcatactcttctgtaagccacatggcccttgtaattgtagcc
tctctcatccaaaccccctgaagcttttccggcgcaaccatccttataatcgctcacgga
ctcacctcttccatgtacttctgcctagccaattcaaactatgaacgcacccacagccgt
accatactactgtcccgaggacttcaaatcctactcccactaacagccttctgatgatta
acagcaagccttactaaccttgccctgccccccactatcaacctactaggcgaactcttt
gtaatcacgacctcattttcctgatcccatatcaccattatgttgacagggcttaatata
ctaattacggccctctactctctccacatattcattacaacgcaacgaggaatacttaca
caccatataatcaacataaaaccctccttcacacgagaaaatatattaatattcatacac
ctcgccccaattatccttctgtctctcaatcccaacatcatcctaggatttacctcct

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (51)   

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