KEGG   Macaca mulatta (rhesus monkey): 715794Help
Entry
715794            CDS       T01028                                 

Gene name
MAPK11
Definition
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc01522  Endocrine resistance
mcc04010  MAPK signaling pathway
mcc04015  Rap1 signaling pathway
mcc04068  FoxO signaling pathway
mcc04071  Sphingolipid signaling pathway
mcc04218  Cellular senescence
mcc04261  Adrenergic signaling in cardiomyocytes
mcc04370  VEGF signaling pathway
mcc04380  Osteoclast differentiation
mcc04550  Signaling pathways regulating pluripotency of stem cells
mcc04611  Platelet activation
mcc04620  Toll-like receptor signaling pathway
mcc04621  NOD-like receptor signaling pathway
mcc04622  RIG-I-like receptor signaling pathway
mcc04625  C-type lectin receptor signaling pathway
mcc04657  IL-17 signaling pathway
mcc04658  Th1 and Th2 cell differentiation
mcc04659  Th17 cell differentiation
mcc04660  T cell receptor signaling pathway
mcc04664  Fc epsilon RI signaling pathway
mcc04668  TNF signaling pathway
mcc04670  Leukocyte transendothelial migration
mcc04714  Thermogenesis
mcc04722  Neurotrophin signaling pathway
mcc04723  Retrograde endocannabinoid signaling
mcc04728  Dopaminergic synapse
mcc04750  Inflammatory mediator regulation of TRP channels
mcc04912  GnRH signaling pathway
mcc04914  Progesterone-mediated oocyte maturation
mcc04917  Prolactin signaling pathway
mcc04926  Relaxin signaling pathway
mcc04933  AGE-RAGE signaling pathway in diabetic complications
mcc05014  Amyotrophic lateral sclerosis (ALS)
mcc05132  Salmonella infection
mcc05133  Pertussis
mcc05140  Leishmaniasis
mcc05142  Chagas disease (American trypanosomiasis)
mcc05145  Toxoplasmosis
mcc05152  Tuberculosis
mcc05160  Hepatitis C
mcc05163  Human cytomegalovirus infection
mcc05164  Influenza A
mcc05167  Kaposi's sarcoma-associated herpesvirus infection
mcc05169  Epstein-Barr virus infection
mcc05205  Proteoglycans in cancer
mcc05418  Fluid shear stress and atherosclerosis
Module
mcc_M00689  MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    715794 (MAPK11)
   04010 MAPK signaling pathway
    715794 (MAPK11)
   04370 VEGF signaling pathway
    715794 (MAPK11)
   04668 TNF signaling pathway
    715794 (MAPK11)
   04068 FoxO signaling pathway
    715794 (MAPK11)
   04071 Sphingolipid signaling pathway
    715794 (MAPK11)
 Cellular Processes
  Cell growth and death
   04218 Cellular senescence
    715794 (MAPK11)
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    715794 (MAPK11)
 Organismal Systems
  Immune system
   04611 Platelet activation
    715794 (MAPK11)
   04620 Toll-like receptor signaling pathway
    715794 (MAPK11)
   04621 NOD-like receptor signaling pathway
    715794 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    715794 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    715794 (MAPK11)
   04660 T cell receptor signaling pathway
    715794 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    715794 (MAPK11)
   04659 Th17 cell differentiation
    715794 (MAPK11)
   04657 IL-17 signaling pathway
    715794 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    715794 (MAPK11)
   04670 Leukocyte transendothelial migration
    715794 (MAPK11)
  Endocrine system
   04912 GnRH signaling pathway
    715794 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    715794 (MAPK11)
   04917 Prolactin signaling pathway
    715794 (MAPK11)
   04926 Relaxin signaling pathway
    715794 (MAPK11)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    715794 (MAPK11)
  Nervous system
   04728 Dopaminergic synapse
    715794 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    715794 (MAPK11)
   04722 Neurotrophin signaling pathway
    715794 (MAPK11)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    715794 (MAPK11)
  Development
   04380 Osteoclast differentiation
    715794 (MAPK11)
  Environmental adaptation
   04714 Thermogenesis
    715794 (MAPK11)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    715794 (MAPK11)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    715794 (MAPK11)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    715794 (MAPK11)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    715794 (MAPK11)
  Infectious diseases
   05132 Salmonella infection
    715794 (MAPK11)
   05133 Pertussis
    715794 (MAPK11)
   05152 Tuberculosis
    715794 (MAPK11)
   05164 Influenza A
    715794 (MAPK11)
   05160 Hepatitis C
    715794 (MAPK11)
   05163 Human cytomegalovirus infection
    715794 (MAPK11)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    715794 (MAPK11)
   05169 Epstein-Barr virus infection
    715794 (MAPK11)
   05145 Toxoplasmosis
    715794 (MAPK11)
   05140 Leishmaniasis
    715794 (MAPK11)
   05142 Chagas disease (American trypanosomiasis)
    715794 (MAPK11)
  Drug resistance
   01522 Endocrine resistance
    715794 (MAPK11)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     715794 (MAPK11)
Protein kinases [BR:mcc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   715794 (MAPK11)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo APH RIO1 Cas_CT1975 Kinase-like Haspin_kinase HABP4_PAI-RBP1
Motif
Other DBs
NCBI-GeneID: 715794
NCBI-ProteinID: XP_001112524
Ensembl: ENSMMUG00000014107
Position
10
AA seq 364 aa AA seqDB search
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFHGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt
atgtcgggccctcgcgccggcttctaccggcaggagctgaacaagaccgtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctcgggcgcctacggctccgtctgttcg
gcctacgacgcgcggctgcgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctgatccacgcgcgcaggacgtaccgggagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggcttctggacgtcttcacgccggccacgtccatcgaggacttcagc
gaagtgtacttggtgaccaccctcatgggtgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgttcagttcctggtttaccaactgctgcgcgggctaaagtac
atccactcggccgggatcatccaccgggacctgaagcccagcaacgtggctgtgaacgag
gactgtgagctcaggatcctggacttcgggctggcgcgccaggcagatgaggagatgacc
ggctacgtggccacgcgctggtaccgggcacctgagataatgctaaactggatgcattac
aaccagacagtggacatctggtccgtgggctgcatcatggctgagctgctccagggcaag
gccctcttcccgggaagcgactacattgaccagctgaagcgcatcatggaagtggtgggc
acacccagccccgaggttctggcaaagatctcctcggaacacgcccggacatacatccag
tccctgccccccatgccccagaaggacctgagcagcatcttccatggagccaaccccctg
gccatagacctccttggaaggatgctggtgctggacagtgaccagagggtcagtgctgcc
gaggcattggcccatgcctacttcagccagtaccatgaccctgaggatgagccagaggcc
gagccgtatgatgagagcgttgaggctaaggagcgcacgctggaggagtggaaggagctc
acctaccaggaagtcctcagcttcaagcccccagagccaccgaagccacctggcagcctg
gagattgagcagtga

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