KEGG   Mycobacterium canettii CIPT 140010059: MCAN_05141
Entry
MCAN_05141        CDS       T01585                                 
Symbol
hemD
Name
(GenBank) putative uroporphyrin-III C-methyltransferase HEMD (uroporphyrinogen III methylase) (urogen III methylase) (SUMT) (urogen III methylase) (UROM)
  KO
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
mce  Mycobacterium canettii CIPT 140010059
Pathway
mce00860  Porphyrin metabolism
mce01100  Metabolic pathways
mce01110  Biosynthesis of secondary metabolites
mce01120  Microbial metabolism in diverse environments
mce01240  Biosynthesis of cofactors
Module
mce_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
mce_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:mce00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    MCAN_05141 (hemD)
Enzymes [BR:mce01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     MCAN_05141 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     MCAN_05141 (hemD)
SSDB
Motif
Pfam: HEM4 TP_methylase
Other DBs
NCBI-ProteinID: CCC42854
Position
613581..615269
AA seq 562 aa
MTRGRKPRPGRIVFVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPEPVLALIGTDLPPV
SGPAPAEPVAGNGDAAGGGSAQEQGRAASAVVSGGPDIRPALGDPADVAKTLTAEARSGV
DVVRLVAGDPLTVDAVISEVNAVARTHLHIEIVPGLAASSAVPTYAGLPLGSSHTVADVR
GDVDWDALAAAPGPLILQATASHLAESARSLIDHQLAESTPCVVTAHGTTCQQRSVETTL
QGLTDPAVLGAADPACSANGRDSQAGPLIVTIGKTVTSRAKLNWWESRALYGWTVLVPRT
KDQAGEMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWIVFTSTNAVRA
VWEKFGEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSLGLLDDFPPYDS
VFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPATTREMIKTGGFDA
VCFTSSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPDTAAIGPLVDALA
EHAARLRAEGALPPPRKKSRRR
NT seq 1689 nt   +upstreamnt  +downstreamnt
atgacgcgagggcgtaagccgagaccgggccgcatcgttttcgtgggctccggtccgggc
gaccccggcttgcttacgacacgggctgccgcggtgctggccaacgccgcgctggtgttc
accgatcccgacgtaccggagccggtgctggcgctgatcggcacggatctgccccccgtg
tccggcccggcgcccgccgagccggttgccgggaacggcgatgcggccggcggaggaagt
gcgcaggaacaaggccgggccgcgtccgcggtagtctccggtggtcctgacatccgcccg
gcgctgggcgatcccgccgatgtggccaagacgctgaccgccgaggcccgttcgggtgtc
gacgtggtgcggctggtggcgggcgatccgctcacggtggatgcggtaatcagcgaggtg
aacgccgtcgcacgcacccacctgcacatcgaaatcgtgcccggcctggccgccagcagc
gcggtcccgacctatgccgggttgccgctgggttcgtcgcacaccgtcgccgacgtgcgc
ggcgatgtggactgggacgcgctggctgccgcacccgggccgctgatcctgcaggccacc
gcatcgcatctagccgaatcggcccgcagcctgatcgatcaccagctggccgagtccact
ccgtgcgtggtgaccgcacacggcaccacctgtcagcagcgttcggtcgagaccacactt
cagggattgaccgacccggcagtcctgggcgctgccgaccccgcgtgctccgcaaacggg
agggactcccaggccggaccgctgatagtgaccatcggcaagacggtgaccagtcgggca
aagctgaactggtgggagagccgcgctctctacggctggacggtgttggtgccgcgcacc
aaggaccaggccggcgagatgagcgagcggctcacgtcgtacggcgcgctgccggtggag
gtgccgaccatcgccgtcgagccgccgcgcagccccgcgcagatggagcgcgccgtcaag
ggcctggtcgatggccgattccagtggatcgtgttcacctccaccaacgcggtgcgtgcg
gtgtgggagaagttcggcgagttcggtttggatgcccgcgcgttctccggggtgaagatc
gcctgtgtcggcgagtcgacggccgaccgggtgcgcgccttcggaatcagtcccgagctg
gtgccctccggggagcagtcctcgcttggcttgctagacgacttcccgccctacgacagc
gttttcgacccggtgaaccgggttttgctgccgcgcgccgacatcgccaccgaaacgctg
gccgagggactgcgagagcgtggctgggagatcgaggacgtcaccgcctaccggaccgtg
cgggccgcgccgccgccggccactacccgggaaatgatcaagacgggcgggtttgacgcg
gtatgtttcacctccagctcgacggtgcgaaacctggtcggcatcgccggcaagccgcac
gcgcggacgatcatcgcctgcatagggccaaagaccgccgagaccgcagccgagttcggc
ttgcgggtcgatgtccagccggacaccgccgccatcggcccgctggtcgatgcgctggcc
gagcatgccgcccggttgcgcgctgagggtgcgctgcccccgccgcgcaagaagagccgc
aggcgctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (5)   
   KEGG MODULE (5)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (28)   

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