KEGG   Monodelphis domestica (gray short-tailed opossum): 100012447
Entry
100012447         CDS       T01031                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase 3 beta
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521  EGFR tyrosine kinase inhibitor resistance
mdo04012  ErbB signaling pathway
mdo04062  Chemokine signaling pathway
mdo04110  Cell cycle
mdo04150  mTOR signaling pathway
mdo04151  PI3K-Akt signaling pathway
mdo04310  Wnt signaling pathway
mdo04340  Hedgehog signaling pathway
mdo04360  Axon guidance
mdo04390  Hippo signaling pathway
mdo04510  Focal adhesion
mdo04550  Signaling pathways regulating pluripotency of stem cells
mdo04657  IL-17 signaling pathway
mdo04660  T cell receptor signaling pathway
mdo04662  B cell receptor signaling pathway
mdo04722  Neurotrophin signaling pathway
mdo04728  Dopaminergic synapse
mdo04910  Insulin signaling pathway
mdo04916  Melanogenesis
mdo04917  Prolactin signaling pathway
mdo04919  Thyroid hormone signaling pathway
mdo04931  Insulin resistance
mdo04932  Non-alcoholic fatty liver disease
mdo04934  Cushing syndrome
mdo04935  Growth hormone synthesis, secretion and action
mdo04936  Alcoholic liver disease
mdo05010  Alzheimer disease
mdo05020  Prion disease
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05135  Yersinia infection
mdo05160  Hepatitis C
mdo05162  Measles
mdo05163  Human cytomegalovirus infection
mdo05165  Human papillomavirus infection
mdo05167  Kaposi sarcoma-associated herpesvirus infection
mdo05200  Pathways in cancer
mdo05210  Colorectal cancer
mdo05213  Endometrial cancer
mdo05215  Prostate cancer
mdo05217  Basal cell carcinoma
mdo05224  Breast cancer
mdo05225  Hepatocellular carcinoma
mdo05226  Gastric cancer
mdo05415  Diabetic cardiomyopathy
mdo05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100012447 (GSK3B)
   04310 Wnt signaling pathway
    100012447 (GSK3B)
   04340 Hedgehog signaling pathway
    100012447 (GSK3B)
   04390 Hippo signaling pathway
    100012447 (GSK3B)
   04151 PI3K-Akt signaling pathway
    100012447 (GSK3B)
   04150 mTOR signaling pathway
    100012447 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100012447 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100012447 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    100012447 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100012447 (GSK3B)
   04657 IL-17 signaling pathway
    100012447 (GSK3B)
   04662 B cell receptor signaling pathway
    100012447 (GSK3B)
   04062 Chemokine signaling pathway
    100012447 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100012447 (GSK3B)
   04917 Prolactin signaling pathway
    100012447 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    100012447 (GSK3B)
   04919 Thyroid hormone signaling pathway
    100012447 (GSK3B)
   04916 Melanogenesis
    100012447 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    100012447 (GSK3B)
   04722 Neurotrophin signaling pathway
    100012447 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    100012447 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100012447 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100012447 (GSK3B)
   05225 Hepatocellular carcinoma
    100012447 (GSK3B)
   05226 Gastric cancer
    100012447 (GSK3B)
   05217 Basal cell carcinoma
    100012447 (GSK3B)
   05215 Prostate cancer
    100012447 (GSK3B)
   05213 Endometrial cancer
    100012447 (GSK3B)
   05224 Breast cancer
    100012447 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    100012447 (GSK3B)
   05162 Measles
    100012447 (GSK3B)
   05163 Human cytomegalovirus infection
    100012447 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100012447 (GSK3B)
   05165 Human papillomavirus infection
    100012447 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100012447 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100012447 (GSK3B)
   05020 Prion disease
    100012447 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    100012447 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100012447 (GSK3B)
   05415 Diabetic cardiomyopathy
    100012447 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100012447 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    100012447 (GSK3B)
   04931 Insulin resistance
    100012447 (GSK3B)
   04934 Cushing syndrome
    100012447 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100012447 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdo01001]
    100012447 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mdo03036]
    100012447 (GSK3B)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     100012447 (GSK3B)
Protein kinases [BR:mdo01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   100012447 (GSK3B)
Chromosome and associated proteins [BR:mdo03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    100012447 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH Choline_kinase
Other DBs
NCBI-GeneID: 100012447
NCBI-ProteinID: XP_001363224
Ensembl: ENSMODG00000018216
UniProt: F6PGQ1
Position
4:complement(83627947..83869129)
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPLIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaaaccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagataaggatggcagcaaggtgacaacagtg
gtggcaactcctggacaaggtccagacaggccacaggaagtcagttatacagacactaag
gtgattgggaatgggtcgtttggtgttgtctatcaagccaaactttgtgattcaggagaa
ctagttgccatcaaaaaagtactacaagacaaaagatttaagaacagagagctccagatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactccagtgga
gagaagaaagatgaagtatatcttaatctggtgctggactacgttcctgaaacagtatac
agagttgccagacattatagtcgggccaaacagacgctccctttgatctatgttaagttg
tacatgtatcaactgtttcgaagtttagcctatatccattcctttggaatctgtcatcgg
gatattaaaccacagaacctcttgcttgatcctgatacggctgtcctaaaactttgtgac
tttggaagtgcaaagcagctggttcgaggagagcccaatgtttcctatatctgctctcgc
tactatagagcaccagagttgatctttggagcaactgattacacctctagcatagatgta
tggtctgcaggatgtgtattggctgagctgttgctaggacaaccaatctttccaggagac
agtggtgtggatcagttggtggaaataatcaaggtcctgggaacgccaacacgagagcaa
attcgagaaatgaatccaaactacactgaattcaaatttcctcagattaaggcacatcct
tggactaaggactcgtcaggaacaggacatttcacctcaggagttcgggtcttccgaccc
cgaactccacctgaggcaattgcattatgtagccgtctgctggaatataccccgactgcc
cgattgacacccttggaagcttgtgcacattctttttttgatgaattacgggacccaaat
gtcaaattaccaaatgggcgagatacacctgcactcttcaatttcaccactcaagaactg
tcaagtaatccacctctggctacaatccttatccctccccatgctcggattcaagcagct
gcttcaacccctacaaatgctacagcagcttcagatgctaatgcaggagaccgaggacag
accaataatgcagcgtcagcttcagcctccaactccacctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (45)   
   KEGG PATHWAY (45)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (7)   
   Pfam (7)   
All databases (85)   

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