KEGG   Monodelphis domestica (gray short-tailed opossum): 100026350
Entry
100026350         CDS       T01031                                 
Symbol
GART
Name
(RefSeq) phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00230  Purine metabolism
mdo00670  One carbon pool by folate
mdo01100  Metabolic pathways
mdo01523  Antifolate resistance
Module
mdo_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100026350 (GART)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100026350 (GART)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100026350 (GART)
Enzymes [BR:mdo01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     100026350 (GART)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     100026350 (GART)
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     100026350 (GART)
SSDB
Motif
Pfam: GARS_A Formyl_trans_N GARS_N AIRS_C GARS_C AIRS CPSase_L_D2 ATP-grasp ATP-grasp_3 ATP-grasp_2 ATP-grasp_4 GFO_IDH_MocA Dala_Dala_lig_C Sacchrp_dh_NADP DUF3104 RimK
Other DBs
NCBI-GeneID: 100026350
NCBI-ProteinID: XP_016288641
Ensembl: ENSMODG00000021062
Position
4:14200724..14241425
AA seq 1011 aa
MAVRVLVIGSGGREHTLAWKLAQSQNVRHVIVAPGNAGTANNEKISNSAVSVTDYTLLAQ
FCKDQKIELVVVGPEAPLAAGIVENLTSAGVKCFGPTAEAAQLESSKKFAKEFMDRHEIP
TAKWKAFTTPEEACNFVMSADFPALVIKASGLAAGKGVIVASNKEEACKAIQEIMQDKAF
GAAGDTVVIEEVLEGEEVSCLCFTDGKTVALMPPAQDHKRLLDGDHGPNTGGMGAYCPTP
QVPMDLLLKIKNTILQRTVDGMRQEGIPYIGILYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDFYEVIQSILDGQLSNSLPVWLEDSTAVTVVMASKGYPANYIKGIEITGIPEA
KALGLEVFQAGTALKEDKIVTNGGRVLTVTAIQRDLMSALEEANKGIAIIKFEGAIYRKD
IGYRAISFLKRPRGLTYKESGVDIAAGNELVKKIKPLAKATSRPGCNVDLGGFAGLFDLK
AAGYKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDIHTAETIIAGIAKACEEAGCALLGGETAEMPGIYPPGEYDLAGFAVGAMERDQKLP
QLDRITEGDVIIGIASSGVHSNGFSLVRKIVENSSVQLSSLVPDGCGNQTLGELLLNPTK
IYSRTLLPILRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLEAYIQRYPRIFSWLQHEG
HLSEEEMAKTFNCGIGAVMVVQKDLAEQVLKDIHQHKEEAWIIGNVVTCPTGCSPVKVKH
LIQTMQINGSFSLVNDSLKDCFGVQPKRARVAVLISGTGTNLQSLIDSTKEPTSFAQIVI
VISNKDGVAGLEKAEKAGIPTKVINHKLYKSRTEFDSEIDKVLEEFSIDLICLAGFMRIL
SHPFVQKWNGKILNIHPSLLPSFKGSNAHEQVLKSGVRITGCTVHFVAEEVDAGQIIAQE
AVPVLRGDTIGTLSERVKIAEHKIFPAALQLVANGTVKLGGNGKICWTKEE
NT seq 3036 nt   +upstreamnt  +downstreamnt
atggcagtccgtgtgcttgtgattggcagtgggggaagggaacatacactggcttggaaa
cttgctcagtctcaaaatgtcagacatgtgatagttgccccaggaaatgcaggaacagcc
aacaatgagaaaatttcaaattcagctgtgtcagtcactgattatactttgcttgctcag
ttctgcaaagatcagaagattgaacttgtagttgttggaccagaggctcctcttgctgct
ggaattgttgagaacctgacatctgcaggagtgaaatgttttggacccacagcagaggca
gctcagttagagtccagcaaaaaatttgccaaagagtttatggaccgacatgaaatccct
actgcaaagtggaaggctttcaccacacctgaagaagcctgcaacttcgtcatgagtgca
gactttcctgctctagttataaaggccagtggtctggctgctggaaaaggtgtgattgtg
gctagtaacaaagaagaggcttgcaaagcaattcaagagataatgcaggataaagctttt
ggagctgctggtgatactgttgtaattgaagaagttcttgaaggagaagaggtgtcttgt
ttgtgcttcactgatggtaagactgtggcgcttatgccgccagcccaggaccataagcga
ttattggatggagaccatggccccaatacgggaggaatgggagcttattgtccaacacca
caggttcctatggatctgttattgaaaattaaaaataccattcttcagagaacagtagat
ggcatgcggcaagaaggcattccatatataggaatattgtatgctggtataatgcttacc
aagaatggcccaaaagttctggagtttaattgcagatttggggatccagaatgtcaggta
attcttccacttcttaaaagtgatttttatgaagtaatccaatcaattttagatggtcag
ctttctaattctctgccagtatggcttgaagatagcactgctgtaactgttgtcatggca
agtaaaggctatccagcaaactacatcaaaggcatagagataacaggaattcctgaggct
aaagctttaggcctcgaggtgtttcaagcaggcacagctctgaaagaggataaaatagta
acgaatggtggtagagttcttacagtaacagccatccagagagatctgatgtctgctctt
gaagaagccaacaaaggaatagctattataaaatttgaaggagccatttatagaaaggac
attggctatagagctatctctttcctgaaacggcccagaggcctgacttacaaggaaagt
ggggtggatattgcagctggcaatgaactagttaagaaaattaagcctttggctaaagct
acctccagaccaggatgtaatgtagatcttggaggatttgctggcctcttcgacttgaaa
gcagctggttataaagatccccttctggcttctggaacagatggagttggaaccaaatta
aaaattgcacagcaatgcaataagcatgatactattggtcaagatttggtggcaatgtgt
gtcaatgatattttggctcaaggagcagagcctctcttcttcctagattatttttcctgt
gggaaacttgatattcacacagctgaaactatcattgctggtatagccaaagcatgtgag
gaagcaggatgtgctcttttgggaggtgagacagctgaaatgccaggtatatatccacca
ggagaatatgaccttgcaggttttgctgttggtgccatggagcgggatcaaaagctccct
caactggacaggatcactgagggggatgttatcattggaatagcctcttctggagttcat
agtaatggattcagccttgtaaggaagattgtagaaaattcttctgtccagctctcctct
ttagtgcctgatggatgtggtaatcaaactctaggagaattgttgttaaatccaaccaaa
atttacagccgaacattgttgcctattcttcgatcggggcatgttaaggcctttgctcat
attactggaggaggactactagaaaacatcccaagagttcttccagagaaactaggggtg
gatttggaagcctatatacagaggtaccctagaatattctcatggcttcagcatgaggga
cacctgtcagaagaggaaatggctaagacattcaattgtggaattggagctgtgatggtg
gtacagaaagatctggctgagcaggttctgaaggatatacaccaacataaggaggaggcc
tggataatcgggaacgtagttacttgtcctacagggtgttccccagtgaaagtcaaacat
ctaattcaaacaatgcaaataaatggatcattctcattagtgaatgattctttaaaggat
tgctttggtgtccaaccaaagagagcacgagtggctgttttaatatctggaacaggcaca
aatctccagtctctaatagatagtactaaggaaccaactagctttgcccaaattgttatt
gttatctctaataaagatggagtggctgggctagagaaagcagaaaaagctggtatccct
actaaggtaattaatcataaattatataaaagtcgcacagaatttgacagtgaaattgac
aaagtccttgaagagttctccattgacctaatctgtcttgcaggattcatgagaattttg
tctcatccttttgtccaaaagtggaatggtaaaatactcaacatccacccatcattgctc
ccttcctttaagggttcaaatgcccatgagcaggttcttaaatctggagtcagaatcact
ggttgtacagtgcattttgtggccgaagaagtggatgctggtcagattattgctcaagaa
gctgtcccagtattgagaggtgacactattggaactttatcagaaagagtaaaaatagca
gagcataaaatatttcctgctgctttacagctggtggccaatggtacagtaaaacttgga
ggaaatggaaagatttgttggactaaagaagaataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (16)   
   Pfam (16)   
All databases (85)   

Download RDF
DBGET integrated database retrieval system