KEGG   Monodelphis domestica (gray short-tailed opossum): 100028991
Entry
100028991         CDS       T01031                                 
Symbol
PTPN11
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 11
  KO
K07293  tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04014  Ras signaling pathway
mdo04072  Phospholipase D signaling pathway
mdo04148  Efferocytosis
mdo04360  Axon guidance
mdo04625  C-type lectin receptor signaling pathway
mdo04630  JAK-STAT signaling pathway
mdo04650  Natural killer cell mediated cytotoxicity
mdo04660  T cell receptor signaling pathway
mdo04670  Leukocyte transendothelial migration
mdo04722  Neurotrophin signaling pathway
mdo04920  Adipocytokine signaling pathway
mdo04931  Insulin resistance
mdo05168  Herpes simplex virus 1 infection
mdo05205  Proteoglycans in cancer
mdo05208  Chemical carcinogenesis - reactive oxygen species
mdo05211  Renal cell carcinoma
mdo05220  Chronic myeloid leukemia
mdo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100028991 (PTPN11)
   04630 JAK-STAT signaling pathway
    100028991 (PTPN11)
   04072 Phospholipase D signaling pathway
    100028991 (PTPN11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100028991 (PTPN11)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100028991 (PTPN11)
   04650 Natural killer cell mediated cytotoxicity
    100028991 (PTPN11)
   04660 T cell receptor signaling pathway
    100028991 (PTPN11)
   04670 Leukocyte transendothelial migration
    100028991 (PTPN11)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100028991 (PTPN11)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100028991 (PTPN11)
  09158 Development and regeneration
   04360 Axon guidance
    100028991 (PTPN11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100028991 (PTPN11)
   05208 Chemical carcinogenesis - reactive oxygen species
    100028991 (PTPN11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100028991 (PTPN11)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    100028991 (PTPN11)
   05211 Renal cell carcinoma
    100028991 (PTPN11)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100028991 (PTPN11)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100028991 (PTPN11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mdo01009]
    100028991 (PTPN11)
Enzymes [BR:mdo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     100028991 (PTPN11)
Protein phosphatases and associated proteins [BR:mdo01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    100028991 (PTPN11)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc PTPlike_phytase Y_phosphatase3
Other DBs
NCBI-GeneID: 100028991
NCBI-ProteinID: XP_001378873
Ensembl: ENSMODG00000003120
Position
3:complement(496901138..496973026)
AA seq 593 aa
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQDLKYD
VGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGAMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPTDPGGVLDFLEEVHHKQESIPDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTTGDQSPLLPCTPTPTCPEMREDSARVYENVGLVQQQKSFR
NT seq 1782 nt   +upstreamnt  +downstreamnt
atgacatcccggagatggtttcacccaaatatcactggagtggaggcagaaaatttactg
ctgacacgaggtgttgatggcagcttcttggccaggcccagtaagagcaatccaggagac
ttcacactttctgttaggcggaatggtgctgtcactcacatcaagattcagaatactggc
gactattatgacctgtatggaggggaaaagtttgccacgctggctgagttagtacagtat
tacatggagcatcatggacaattgaaagaaaagaatggtgacgttattgagctcaaatat
cccctcaactgtgcagatcctacctcggaaaggtggtttcatgggcacctttctgggaaa
gaagcagagaaattattaactgagaaaggaaaacatggaagcttcctcgtgcgggaaagc
cagagccacccgggggattttgttctctctgtccgcacgggggacgataaaggagagagt
aatgatggcaaatcaaaagtgacgcacgtcatgattcgctgtcaggatctgaaatatgat
gttggtggaggagagaagtttgactctttaacagaccttgtggagcattacaagaagaac
cctatggtagaaactttgggtacagttctacagctcaagcagcctctgaatacaactcgt
atcaatgctgcagagattgaaagccgggtgagagaattaagcaaattagccgagaccaca
gataaagttaaacaagggttttgggaagaatttgagactcttcaacagcaggaatgcaag
ctcctctatagtcgtaaagaaggtcagcggcaagaaaataaaaacaaaaacagatataag
aatattttgccctttgatcataccagggttgtcctacatgatggggatccaaatgaacca
gtttcagattatattaatgcaaatattatcatgcctgaatttgagaccaaatgcaacaat
tcaaaacccaaaaagagttatattgcaacccaaggctgtcttcagaacacagtgaacgac
ttctggagaatggtgttccaggagaattcacgagttattgtcatgacgacgaaagaagta
gagagagggaagagtaaatgtgtcaagtactggcctgatgaatatgctctaaaggaatat
ggggctatgcgcgttaggaatgtcaaagaaagtgctgctcatgactatacattacgagaa
ctaaaactctctaaggttggacaagggaacacggagcgaactgtgtggcagtaccatttt
agaacctggcctgatcacggtgtgcccactgaccctgggggtgttctggactttttagaa
gaggtccatcacaagcaggagagcattcctgatgcaggccctgtggtggtgcattgcagt
gctgggattggcaggacaggaacttttattgtgattgacatccttattgacattatcaga
gaaaaaggtgtggattgtgacattgatgttcccaagacgattcagatggtgagatcccag
aggtcagggatggtccaaaccgaagcccagtacagatttatctacatggctgtgcagcat
tatattgagacgctgcagcgcagaatcgaagaggaacagaaaagcaagagaaaaggacat
gaatatacaaacattaaatattccctagcggaccagacaactggagatcagagtcctcta
ctaccctgcacaccgactccaacctgtccagaaatgagagaagatagtgctagagtatat
gaaaatgtgggattggtgcagcagcagaaaagttttagatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (46)   

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