KEGG   Marinithermus hydrothermalis: Marky_0958
Entry
Marky_0958        CDS       T01457                                 
Name
(GenBank) Ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
mhd  Marinithermus hydrothermalis
Pathway
mhd00290  Valine, leucine and isoleucine biosynthesis
mhd00770  Pantothenate and CoA biosynthesis
mhd01100  Metabolic pathways
mhd01110  Biosynthesis of secondary metabolites
mhd01210  2-Oxocarboxylic acid metabolism
mhd01230  Biosynthesis of amino acids
Module
mhd_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:mhd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Marky_0958
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    Marky_0958
Enzymes [BR:mhd01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     Marky_0958
SSDB
Motif
Pfam: IlvN IlvC 2-Hacid_dh_C F420_oxidored NAD_binding_2 CoA_binding AdoHcyase_NAD Rossmann-like Nitro_FeMo-Co CoA_binding_2
Other DBs
NCBI-ProteinID: AEB11702
UniProt: F2NQH5
Position
931894..932919
AA seq 341 aa
MQVYYDHDADLEVIRRKTVAVLGFGSQGHAHAQNLKDAGVPVVVGLRPGSARWAAAEAAG
LEVLEVAEAVRRAEVVMVLLPDEAQAGVYREAIAPNLKEGAALAFAHGFNIHFGQIRPRP
DLDVWMVAPKGPGHLVRSEYAAGRGVPALVAVAQDASGSAFQTALAYAKAIGATRAGVIP
TTFAEETETDLFGEQAVLCGGLTRLIAYGFETLVEAGYKPEIAYFEVLHEMKLIVDLLYE
SGLAGMRYSISNTAEYGDYTRGDAVLPPETKERMRAVLQEIRSGVFAREWILENQAGRPV
LEARRRQWARHPIEAIGPKLRAMMPFLKARIAEEEVGRASD
NT seq 1026 nt   +upstreamnt  +downstreamnt
atgcaggtgtactacgatcacgacgcggacctcgaggtcatccggaggaagaccgttgcg
gtgctcggtttcggctcgcaagggcacgcgcacgcccagaacctcaaggacgcgggggtg
cccgtggtggtggggttgcgccccggctcggcccgctgggctgcggccgaggcggcgggc
ctcgaggtcctggaggtggcggaggccgtgcgccgggcggaggtggtgatggtcctcctg
cccgacgaggcgcaggccggggtgtaccgggaggcgatcgcgccgaacctgaaggagggg
gcggccctggccttcgcgcacgggttcaacatccacttcggccagatccggccccggccc
gacctggacgtgtggatggtggcccccaaggggcccggccacctggtgcgcagcgagtac
gcggccggccgcggggtgcccgccttggtcgccgtggcgcaggacgcttcggggagcgcc
ttccagacggccctcgcttacgcgaaggccatcggggcgacgcgggcgggggtgatcccc
accaccttcgccgaggagaccgagaccgacctcttcggcgagcaggcggtcttgtgcggc
ggcctgacccggctcatcgcctacgggttcgagaccctggtggaggctgggtacaagccg
gagatcgcgtactttgaggttctgcacgagatgaagctcatcgtggacctcctgtacgag
tccggcctggcggggatgcggtactcgatctcgaacaccgcggagtacggggactacacc
cgcggcgacgcggttctcccgccggaaacgaaggagcgcatgcgggcggtgctccaggag
atccgctccggtgtgttcgcccgggaatggatcctggagaaccaggcgggccggccggtg
ctcgaggcgcgccgccggcagtgggcacgccaccccatcgaggcgatcggccccaaactg
cgagccatgatgccgttcttgaaggcccgcatcgcggaggaggaggtgggccgtgcgtcg
gattaa

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