KEGG   Marinithermus hydrothermalis: Marky_0960
Entry
Marky_0960        CDS       T01457                                 
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
mhd  Marinithermus hydrothermalis
Pathway
mhd00290  Valine, leucine and isoleucine biosynthesis
mhd00620  Pyruvate metabolism
mhd01100  Metabolic pathways
mhd01110  Biosynthesis of secondary metabolites
mhd01210  2-Oxocarboxylic acid metabolism
mhd01230  Biosynthesis of amino acids
Module
mhd_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mhd00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Marky_0960
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Marky_0960
Enzymes [BR:mhd01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Marky_0960
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AEB11704
UniProt: F2NL85
Position
934435..936033
AA seq 532 aa
MRQSAAIEVLDTTLRDGTQGEGFVLSTEDKVAIARRLAAFGVPLIEGGWPGSNPKDAAFF
QRMKGVDLGAARLVAFGATHRKGLRPEADPSVQALLEARTPVVTLFGKSWTLHVREALGV
NLEEHLWMIEATVAHLVRQGRRVIYDAEHFFDGFKEDPAYAMETLRVALRGGADTLVLCD
TNGGSLPEEVYEITRRVVDTFPRVRIGIHAHNDAELAVANTLAAVRAGARHVQGTIGGYG
ERCGNANLVSLIPTLMLKYGYAVVPRPRLAELKVLARFVDERANLTPNRRAPYVGEAAFA
HKGGVHVSAVLKNPRTYEHIDPQLVGNARRILVSDLAGRSNLLAKLAERGLELEAETARS
LLEEVKALEHAGYAFEGAEASFYLLAHRLRGGRLPFVVRAFRAWVQGEARGAWQAEATVQ
VQVGAEVYHTAAMGEGPVGALDNALRKALLAFYPELEGVELADYKVRVLSGQERGTASGV
RVLVEMTDGKDRWGTVGASVNILEASLKALADGYAYVLVKEARAPHQAHKAS
NT seq 1599 nt   +upstreamnt  +downstreamnt
atgaggcaatccgcggcgatcgaggtgctggacaccacactgcgcgacggcacgcagggt
gagggcttcgtgctctccaccgaggacaaggtagccatcgcgcggcggctcgcggccttc
ggggtgcccctcatcgagggggggtggcccggctcgaaccccaaagacgcggcgttcttc
cagcgcatgaagggcgtggacctcggcgcggcccgcctcgtggcgttcggcgcgacccac
cgcaaggggctccgccccgaggcggacccttcggtccaggccctcctcgaggcaaggacc
cccgtggtgaccctcttcggcaagtcctggacgctgcacgtccgggaagccctcggggtg
aacctcgaggagcatctctggatgatcgaggcgaccgtcgcgcacctggtgcggcagggg
cggcgcgtgatctacgacgcggagcacttcttcgacgggtttaaggaagaccccgcctac
gcgatggagacgctgcgtgtcgcgttgcggggcggggcggacaccctggtcctgtgcgac
acgaacgggggaagcctgccggaggaggtctacgagatcacccggcgggtggtggacacc
ttcccccgggtgcgcatcgggatccacgcgcacaacgacgcggagctcgcggtggccaac
accctggccgcggtgcgggcgggagcgcggcacgtgcagggcaccatcggcgggtacggg
gagcggtgcgggaacgcgaacctcgtcagcctgatccccaccctgatgctgaagtacggg
tacgcggtcgtgcctcgcccgcgccttgcggagctgaaggtgctcgcgcggttcgtggac
gaacgcgcgaacctcacccccaaccgccgcgcgccgtacgtgggggaggcggccttcgcg
cacaagggcggggtgcacgtctccgcggtgctcaaaaacccgcgcacctacgagcacatt
gacccccagctggtgggtaacgcgcgccgcatcctcgtctcggaccttgcggggcgctcg
aacctgctcgccaagctcgccgagcgcggcctcgagctcgaggcggaaacggcccgctcc
cttttggaggaggtcaaggccctcgagcacgccgggtacgccttcgagggggccgaggcc
tcgttctacctgctcgcgcaccggctccggggcggacggctgccctttgtggtccgggcg
tttcgcgcctgggtgcagggggaggcgcgcggggcgtggcaggccgaggcgaccgtgcag
gtccaggtgggcgcggaggtctaccacaccgccgcgatgggcgaggggccggtaggggcg
ctggacaacgcgctccgcaaggccctcctcgccttctatcccgagctcgagggggtcgag
ctggcggactacaaggtgcgggtcctctccgggcaggagcggggtaccgcgagcggcgtg
cgggttttggtggagatgacggacggaaaagaccgctggggaacggtcggcgccagcgtg
aacatcctcgaggcctccctcaaggccctggccgacgggtacgcgtacgtgctagtgaaa
gaagcgcgcgcgccacaccaggcccacaaagcgagctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (25)   

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