KEGG   Mesorhizobium huakuii: MCHK_4353
Entry
MCHK_4353         CDS       T06432                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
mhua  Mesorhizobium huakuii
Pathway
mhua00290  Valine, leucine and isoleucine biosynthesis
mhua00620  Pyruvate metabolism
mhua01100  Metabolic pathways
mhua01110  Biosynthesis of secondary metabolites
mhua01210  2-Oxocarboxylic acid metabolism
mhua01230  Biosynthesis of amino acids
Module
mhua_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mhua00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    MCHK_4353 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MCHK_4353 (leuA)
Enzymes [BR:mhua01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     MCHK_4353 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AID32154
Position
complement(2180569..2182314)
AA seq 581 aa
MNAREQIRPDAAVAGKHVEPARGMPDAARKYQPYPTVGLTDRTWPSKVIDKAPIWCSVDL
RDGNQALIDPMGHERKARMFGLLLDMGFKEIEIGFPSASQTDFDFARWCIEEGNVPADVS
LQVLVQCRPELITRTFEALKGATNPIVHFYNSTSELQRRVVFEKDVGGIKRIATDAAKMI
TDMAAKAGGGYRFEYSPESFTGTELEVALEICNAVTEIVRPTPDNKLIINLPSTVEMSTP
NIYADRIEWMCRNLDARENLIISLHPHNDRGTGIATTELGLMAGADRVEGTLFGNGERTG
NVDIVTLALNMYTQGVDPGIDCSDINRMKDVYEYSNQLKIPERHPYVGELVYTAFSGSHQ
DAINKGMKALKKANTSLWEVPYLPIDPADVGRSYEAIIRINSQSGKGGIAYVLQADYGLN
LPRNLQIEFSQAIQAITDAEGKEVPAKRIYERFLETYVDQPGARLKFLDHHTYPDTVVKG
RRVVEAVILDKGKEVTISGTGTGPIDGFVDALSRHVGVEMSVLDYSEHSMQRGSNASAIS
YVEMEYPGGKLFGAGINTNIVAASLEAVTSAANRIVGRKPR
NT seq 1746 nt   +upstreamnt  +downstreamnt
atgaacgcacgagaacagatccgccctgatgccgctgtagcaggcaagcatgtcgaacca
gcccgcggcatgcccgacgcggcccgcaaatatcaaccctatccgaccgttggcctcacc
gaccggacctggccctcgaaggtcatcgacaaggcgccgatctggtgttcggtcgacctg
cgcgacggcaaccaggcactgatcgacccgatgggccatgagcgcaaggcgcgcatgttc
ggcctgctgctcgacatgggattcaaggagatcgagatcggcttcccctcggcctcgcag
accgatttcgacttcgcccgctggtgcatcgaggaaggcaacgtgcccgccgatgtgtcg
ctgcaggtgctggtgcagtgccggcccgagctgatcacgcgcaccttcgaggcgctgaag
ggcgccaccaacccgatcgtgcatttctacaattcgaccagcgaattgcagcgccgcgtc
gtcttcgaaaaggatgtcggcggcatcaagcgcatcgccaccgacgcggccaagatgatc
accgacatggcggccaaggccggcggcggctatcgcttcgaatactcgccggaaagcttt
accggcaccgagctcgaagtcgcgctggagatctgcaacgccgtcaccgagatcgtcagg
ccgacgccggacaacaagctgatcatcaacctgccgtcgacggtcgagatgtcgacgccc
aacatctatgccgaccgcatcgaatggatgtgccgcaatctggacgccagagagaacctg
atcatctcgctgcatccgcacaatgaccgcggcaccggcatcgccaccaccgaactcggc
ttgatggcgggcgcggaccgcgtcgaaggcacgctgttcggcaatggcgagcgcaccggc
aatgtcgacatcgtcacgctggcgctcaacatgtacacacaaggcgtcgatccgggcatc
gactgctccgacatcaaccggatgaaggacgtctatgaatattcgaaccagttgaagatc
cccgagcgtcacccctatgtcggcgaactcgtctacaccgccttttccggctcgcaccag
gacgccatcaacaagggcatgaaggcgctgaaaaaggccaacaccagcctctgggaagtg
ccgtatctgccgatcgacccggccgatgtcggccgcagctacgaggcgatcatccgcatc
aactcgcagtccggcaagggcggcatcgcctatgtgctgcaggccgattacggcctcaat
ctgccgcgcaacctgcagatcgaattcagccaggcgatccaggcgatcaccgatgccgag
ggcaaggaagtgccggccaagcgcatctatgagcgctttctcgaaacctatgtcgaccag
ccgggcgcgcgcctgaaattcctcgaccaccacacctatcccgatacagtggtcaagggc
cggcgcgtggtcgaggcagtgatcctcgacaagggcaaggaagtgaccatatcaggcacc
ggcacaggcccgatcgacggcttcgtcgatgcactgtcacgccatgtcggcgtcgagatg
tcggtgctcgattattccgaacactcgatgcagcgtggctccaatgcatccgccatttcc
tatgtcgaaatggaatatcccggcggcaagctgttcggcgccggcatcaacaccaacatc
gtcgccgcctcgctggaagcggtgacgtcggcagccaaccgcatcgtcggccgcaagccg
cggtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
Protein domain (2)   
   Pfam (2)   
All databases (21)   

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